ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Image analysis"

  • 2022 American Transplant Congress

    Human PBMC-Transferred Murine MHC Class I/II-Deficient NOG Mice Enable Long-Term Evaluation of Human Immune Responses to Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Sheets

    R. Matsumoto

    Center for Immune Therapeutics and Diagnosis, Juntendo University, Tokyo, Japan

    *Purpose: Transplantation of cardiomyocytes sheets derived from allogenic human induced pluripotent stem cells (hiPS-CMs) hold great promise in generating new functional myocardium in situ. However,…
  • 2022 American Transplant Congress

    Pre-Transplant Ex-Vivo Analysis of Kidney Vasculature and Perfusion Using Contrast Computed Tomography

    A. Feizi1, J. R. DiRito1, M. Harris1, J. C. Stendahl1, S. Spindler1, C. M. Edwards1, T. Lysyy1, S. Lee1, N. Boutagy1, A. Fehér1, P. Yoo1, S. A. Hosgood2, D. C. Mulligan1, M. L. Nicholson2, A. J. Sinusas1, D. J. Haakinson1, G. T. Tietjen1

    1Yale School of Medicine, New Haven, CT, 2University of Cambridge, Cambridge, United Kingdom

    *Purpose: Ex-vivo normothermic perfusion (NMP) has been developed with the goal of improving viability of the thousands of donated organs that are declined for transplant…
  • 2022 American Transplant Congress

    Use of Three-Dimensional (3D) Modeling Software for Preoperative Anatomical Assessment in Living Donor Nephrectomy

    M. McCabe1, K. Dokus2, A. Nair2, K. Pineda-Solis2, E. Venniro1, J. Taylor1, M. Orloff2, R. Hernandez1, R. Kashyap2

    1University of Rochester School of Medicine and Dentistry, Rochester, NY, 2University of Rochester Medical Center, Rochester, NY

    *Purpose: Successful and safe completion of living donor nephrectomy depends on donor anatomy. Preoperative imaging is imperative to determine operative feasibility and to avoid unexpected…
  • 2022 American Transplant Congress

    Use of Three-Dimensional Volumetric Analysis to Monitor Acute Rejection in a Face Transplant Recipient

    D. Boczar1, H. Brydges1, O. C. Onuh1, B. F. Chaya1, J. Trilles1, R. Rodriguez Colon1, D. J. Ceradini1, B. E. Gelb2, E. D. Rodriguez1

    1Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, NY, 2Transplant Institute, NYU Langone Health, New York, NY

    *Purpose: The purpose of this study is to determine the feasibility of using 3D facial stereography to monitor volume changes in a facial allograft, and…
  • 2022 American Transplant Congress

    Smartphone-Microfluidic Fluorescence Imaging System for Studying Islet Physiology

    X. Yu, Y. Xing, Y. Zhang, P. Zhang, Y. He, M. K. Ramasubramanian, Y. Wang, H. Ai, J. Oberholzer

    University of Virginia, Charlottesville, VA

    *Purpose: The goal of this study is to develop an innovative smartphone-microfluidic fluorescence imaging (µSFI) system for multi-parameter islet function characterization, which could provide quantitative…
  • 2021 American Transplant Congress

    Multiplexed Imaging Mass Cytometry of the Alloimmune Landscape of Rejection in Clinical Liver Transplantation

    J. Emamaullee, N. Ung, C. Man, J. Hoeflich, C. Goldbeck, A. Barbetta, R. Sun, N. Matasci, J. Katz, J. Lee, S. Chopra, L. Sher, S. Asgharzadeh, O. Akbari, Y. Genyk

    University of Southern California, Los Angeles, CA

    *Purpose: Rejection continues to be an important cause of graft loss and failure post-liver transplant (LT). Imaging Mass Cytometry (IMC) is an emerging preclinical technique…
  • 2021 American Transplant Congress

    The Microenvironment of Belatacept-Resistant Rejection

    A. Johnson, J. Zhang, C. Larsen

    Surgery, Emory University, Atlanta, GA

    *Purpose: Belatacept is a co-stimulation blockade immunosuppressant, that despite demonstrating improved long-term outcomes, has not been widely adopted, in part, due to concern over early…
  • 2021 American Transplant Congress

    Patterns and Inhibition of Cell Death During Static Cold Storage of Human Kidneys

    J. R. DiRito1, G. Chickering2, J. T. Langford1, D. Stern1, S. Hosgood3, M. L. Nicholson3, E. Gavathiotis4, R. N. Kitsis5, M. Saltzman2, J. S. Pober6, G. T. Tietjen7

    1Surgery, Yale School of Medicine, New Haven, CT, 2Biomedical Engineering, Yale University, New Haven, CT, 3Surgery, University of Cambridge, Cambridge, United Kingdom, 4Biochemistry and Medicine, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY, 5Surgery, Albert Einstein College of Medicine, Bronx, NY, 6Immunobiology, Yale University, New Haven, CT, 7Surgery and Biomedical Engineering, Yale School of Medicine, New Haven, CT

    *Purpose: As the donor population continues to age and accumulate co-morbidities, more marginal kidneys are being retrieved for transplantation. However, estimates suggest that more than…
  • 2021 American Transplant Congress

    The Tumor-suppressor Signaling of the α1-na/k-atpase- Cav-1-src Complex at the Caveola in Nash Related Hepatocellular Carcinoma

    U. S. Udoh1, J. D. Sanabria1, M. Banerjee1, P. K. Rajan1, M. Schade1, J. A. Sanabria1, A. Mallick1, G. Smith1, G. U. Udoh2, K. Sodhi1, S. Pierre2, Z. Xie2, J. Shapiro2, J. Sanabria1

    1Dept. of Surgery/ Marshall Institute for Interdisciplinary Research, Marshall University, Huntington,, WV, 2Marshall Institute for Interdisciplinary Research, Marshall University, Huntington,, WV

    *Purpose: Hepatocellular Carcinoma (HCC) is the 2nd and fastest-growing cause of cancer related mortality worldwide, mainly from the metabolic cellular disturbances promoted by the epidemic…
  • 2021 American Transplant Congress

    Novel Morphologic Biomarkers of Cardiac Allograft Remodeling are Associated with Multiple Peri- and Post-transplant Inflammatory Processes

    C. Yuan1, S. Arabyarmohammadi1, H. Li1, E. Peyster2, P. Lal3, M. Feldman3, K. Margulies2, A. Madabhushi1

    1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 2Cardiovascular Research Institute, University of Pennsylvania, Philadelphia, PA, 3University of Pennsylvania, Philadelphia, PA

    *Purpose: It has long been recognized that transplanted hearts develop a stiffened, restrictive physiology at an accelerated rate compared to native hearts. While this is…
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