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Articles tagged "HLA antibodies"

  • 2015 American Transplant Congress

    Clinical Relevance of C3d-Binding Donor-Specific Antibodies in Late Kidney Allograft Failure

    J. Lan, D. Gjertson, Y. Zheng, DeKAF Investigators, E. Reed, M. Cecka.

    Path, UCLA, LA, CA.

    Background: The objective of this study was to investigate the prognostic value of C3d-binding donor-specific antibodies (DSA) in determining late kidney allograft failure.Methods: 1048 patients…
  • 2015 American Transplant Congress

    Repeat Donor HLA Mismatch Antigens and Kidney Transplant Outcome

    P. Lokhandwala,1 M. Wang,2 Z. Kadry,3 R. Shah,3 A. Jain,3 J. Gaspari,1 N. Ghahramani,4 C. Abendroth,1 H. Shike.1

    1Pathology, Penn State Hershey Medical Center, Hershey, PA; 2Public Health Sciences, Penn State College of Medicine, Hershey; 3Transplant Surgery, PSHMC, Hershey; 4Nephrology, PSHMC, Hershey.

    Background: Historically, poorer outcome has been reported in kidney re-transplant patients with repeat HLA mismatch antigens. Transplant practice has evolved. Risk of repeat mismatch antigen…
  • 2015 American Transplant Congress

    Clinical Significance of Estimated DSA MFI Values at 1,000 C1q MFI for Differentiation Between Harmful and Harmless DSA

    K. Horimi,1 T. Akaza,2 K. Kuroki,2 S. Sakamoto,2 Y. Matsuoka,1 Y. Watarai,2 S. Narumi,2 A. Katayama,3 K. Uchida,1 T. Kobayashi.4

    1Aichi Medical University, Nagkute, Japan; 2Nagoya Daini Red Cross Hospital, Nagoya, Japan; 3Masuko Memorial Hospital, Nagoya, Japan; 4Nagoya University School of Medicine, Nagoya, Japan.

    INTRODUCTIONControl of chronic antibody mediated rejection (CAMR) is essential for further improvement of long-term graft survival. Early detection of de novo donor specific antibodies (DSA)…
  • 2015 American Transplant Congress

    Impact of Positive Crossmatch Due to Non-HLA Antibodies on Graft Outcomes in Renal Transplantation

    S. Kuten, S. Patel, G. Land, T. Eagar, R. Knight, J. Loucks, L. Gaber, A. Gaber.

    Houston Methodist Hospital, Houston, TX.

    It is widely recognized that a positive allogeneic crossmatch (+alloXM) due to pre-existing human leukocyte antigen (HLA) antibodies is associated with early rejection episodes. However,…
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