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Articles tagged "HLA antibodies"

  • 2015 American Transplant Congress

    De Novo DSA Would Not Necessarily Cause Graft Rejection After Renal Transplantation: Characteristics of DSA Developing Biopsy-Proven Chronic Antibody-Mediated Rejection

    T. Yamamoto, Y. Watarai, A. Takeda, M. Okada, M. Tsujita, H. Takahisa, N. Goto, S. Narumi, T. Kobayashi.

    Kidney Center, Nagoya Daini Red Cross Hospital, Nagoya, Japan.

    Introduction:De novo donor-specific HLA antibodies (dn DSA) production after renal transplantation has been reported to be associated with chronic antibody mediated rejection (CAMR), which leads…
  • 2015 American Transplant Congress

    The Higher MFI of De Novo Donor-Specific Anti-HLA Antibodies Is Correlated With Graft Fibrosis Progression in Living Donor Liver Transplantation

    Y. Fukasaku,1 R. Goto,1 S. Emoto,1 N. Kawamura,1 Y. Koshizuka,1 T. Takahashi,1 M. Ota,3 T. Aoyagi,1 K. Yamashita,2 A. Taketomi,1 T. Shimamura.3

    1Gastroenterological Surgery 1, Hokkaido University, Sapporo, Japan; 2Transplant Surgery, Hokkaido University, Sapporo, Japan; 3Division of Organ Transplantation, Hokkaido University Hospital, Sapporo, Japan.

    Background. It has been shown that the development of de novo donor-specific anti-HLA antibodies (DSA) is associated with poorer graft outcome in kidney transplantation. However…
  • 2015 American Transplant Congress

    The Effect of Preformed and De Novo Donor-Specific Antibodies (DSA) in Acute Rejection (AR) After Liver Transplantation (LTX)

    M. Koch,1 M. Runnebaum,1 M. Goebel,2 H. Thude,1 M. Sterneck,1 M. Marget,2 B. Nashan.1

    1Hepatobiliary Surgery and Transplantation, University Medical Centre, Hamburg, Germany; 2HLA-Laboratory, University Medical Centre, Hamburg, Germany.

    BACKGROUND: The role of preformed and den novo formed DSA in LTX is not fully revealed. The aim of our study was to determine if…
  • 2015 American Transplant Congress

    Interference of Therapeutic Antibodies Used in Desensitization Protocols On Lymphocytotoxicity Crossmatch Results

    D. Milongo,1,3 G. Vieu,2,4,3 S. Blavy,2,4 A. Del Bello,1,3 F. Sallusto,5 L. Rostaing,1,3 N. Kamar,1,3 N. Congy-Jolivet.2,4,3

    1Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Laboratoire d'Immunologie, CHU de Toulouse, Toulouse, France; 3Université Toulouse III Paul-Sabatier, Toulouse, France; 4Laboratoire d'Immunogénétique Moléculaire, EA 3034, Université Toulouse III Paul-Sabatier, Toulouse, France; 5Department of Urology, CHU Rangueil, Toulouse, France.

    Background: Therapeutic antibodies used to desensitize patients awaiting a human leukocyte antigen (HLA) or ABO-mismatched graft are suspected to interfere with the lymphocytotoxicity crossmatch (LCT-XM)…
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