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Articles tagged "HIV virus"

  • 2019 American Transplant Congress

    Hope in Action: A Multicenter Prospective Study of HIV to HIV Kidney Transplantation

    C. Durand1, S. Huprikar2, M. Bowring3, D. Brown1, B. Haydel4, N. Desai3, F. Naqvi1, R. Friedman-Moraco5, N. Turgeon6, V. Stosor7, J. Charette7, S. Mehta8, J. Husson9, A. Gilbert10, M. Cooper11, C. Butkus-Small12, G. Gupta13, S. Mehta14, O. Adebiyi15, P. Chin-Hong16, P. Stock17, A. Massie3, S. Florman4, D. Segev3

    1Medicine, Johns Hopkins University, Baltimore, MD, 2Medicine, Mount Sinai, New York, NY, 3Surgery, Johns Hopkins University, Baltimore, MD, 4Surgery, Mount Sinai, New York, NY, 5Medicine, Emory University, Atlanta, GA, 6Surgery, Emory University, Atlanta, GA, 7Medicine, Northwestern University, Chicago, IL, 8Medicine, University of Alabama, Birmingham, AL, 9Medicine, University of Maryland, Baltimore, MD, 10Medicine, Georgetown University, Washington DC, DC, 11Department of Surgery, Georgetown University, Washington DC, DC, 12Medicine, Cornell University, New York, NY, 13Medicine, Virginia Commonwealth University, Richmond, VA, 14Medicine, New York University, New York, NY, 15Medicine, Indiana University, Indianapolis, IN, 16Medicine, University of California at San Francisco, San Francisco, CA, 17Surgery, University of California at San Francisco, San Francisco, CA

    *Purpose:HIV+ donor to HIV+ recipient (HIV D+/R+) kidney transplantation (KT) has had success in South Africa. Expansion of this practice in the US setting of…
  • 2019 American Transplant Congress

    Characterization Of Increased Risk Donor Post-transplant Viral Surveillance Protocol At A Comprehensive Transplant Center

    J. Dann, W. Ally, S. Pelletier, C. Sifri, A. Agarwal

    University of Virginia Health System, Charlottesville, VA

    *Purpose: With the growing opioid crisis, the number of deceased donors classified as Increased Risk Donor (IRD) has increased to nearly 20% nationally. The Organ…
  • 2019 American Transplant Congress

    Hope Act Donors With Organs Recovered For Transplant: The First Two Years

    W. A. Werbel, O. Kusemiju, B. Barnaba, M. Bowring, B. Doby, C. Kirby, R. Fernandez, Y. Eby, J. Miller, D. Brown, S. Seaman, D. Ostrander, A. Tobian, D. Segev, C. M. Durand

    Johns Hopkins University, Baltimore, MD

    *Purpose: The HOPE Act expands the potential deceased donor pool to include HIV+ donors (HIV D+) and donors with false-positive (FP) HIV screens. The objective…
  • 2019 American Transplant Congress

    Long Term Outcomes of Patients Transplanted for Hepatocellular Carcinoma with Human Immunodeficiency Virus Infection

    R. Gedaly-Eidelman, E. Chacon, P. Eman, M. Gupta, J. Berger, A. El-Husseini, X. Mei, F. Marti, L. Turcios, M. Shah

    University of Kentucky, Lexington, KY

    *Purpose: Several studies have reported that HIV+ patients are 4-6 times more likely to develop HCC than uninfected individuals. Our aim was to assess outcomes…
  • 2019 American Transplant Congress

    A Single-Center Experience with a 6-Month Regimen of Pneumocystis jiroveci Pneumonia Prophylaxis in HIV-Positive Kidney Transplant Recipients

    C. Mejia1, G. Malat2, D. H. Lee3, S. Epstein1, M. Harhay3, L. Levin Mizrahi3, K. Ranganna3

    1Drexel University, Philadelphia, PA, 2Hahnemann University Hospital, Philadelphia, PA, 3Medicine, Drexel University, Philadelphia, PA

    *Purpose: Pneumocystis jiroveci pneumonia (PJP) prophylaxis is recommended for all kidney transplant recipients (KTR) for after transplant. HIV-positive KTRs represent a unique subset, and there…
  • 2019 American Transplant Congress

    Barriers to Kidney Transplant Wait Listing among HIV Positive Patients with Advanced Kidney Disease

    S. M. Boyle1, K. Fehr1, C. Deering2, A. Raza1, M. Harhay1, G. Malat3, K. Ranganna1, D. Lee1

    1Drexel University, Philadelphia, PA, 2University of Toledo, Toledo, OH, 3Hahnemann University Hospital, Philadelphia, PA

    *Purpose: Compared to HIV-negative kidney transplant (KT) candidates, the median time to waiting list activation is longer among HIV-positive candidates. Little is known about potential…
  • 2019 American Transplant Congress

    The Spread of HIV Donation throughout a DSA

    A. Friedman, E. Marquez, J. A. Lewis, K. Delli Carpini

    LiveOnNY, New York, NY

    *Purpose: Before passage of the HOPE act in late 2013, HIV infection was an absolute contraindication to organ donation. Retrospective review of the records of…
  • 2019 American Transplant Congress

    Impact of Everolimus Therapy on HIV Persistence and Gene Expression in Transplant Patients

    A. Zarinsefat1, C. Schreiner1, C. Cameron2, S. Chu1, M. P. Busch1, T. Liegler1, S. G. Deeks1, T. J. Henrich1, P. G. Stock1

    1UC San Francisco, San Francisco, CA, 2Case Western Reserve University, Cleveland, OH

    *Purpose: mTOR is a key regulatory kinase that controls cell-cycle progression. mTOR inhibitors have been shown to reduce expression of CCR5 and promote viral transcriptional…
  • 2018 American Transplant Congress

    Comparative Analysis of Alloantigen-Stimulated Gene Expression in HIV(+) Liver Transplant Rejectors versus Non-Rejectors

    S. Chu, K. Lee, C. Ward, P. Stock, Q. Tang.

    Surgery, University of California, San Francisco, San Francisco, CA.

    In a multi-center, prospective trial of solid-organ transplantation in persons with HIV, recipients had a 2-3x increased rejection rate when compared to historical data on…
  • 2018 American Transplant Congress

    Higher Rates of Rejection in HIV-Infected Kidney Transplant Recipients on Ritonavir-Boosted Protease Inhibitors–Three-Year Follow Up

    B. Rollins, S. Farouk, G. DeBoccardo, S. Lerner, M. Rana, S. Huprikar, L. Miko, V. Delaney, S. Florman, R. Shapiro.

    The Mount Sinai Hospital, New York.

    Background: One-year rejection rates in HIV-infected kidney transplant recipients range from 15-40%, compared to overall rejection rates of 10% in HIV-negative patients. Protocols for immunosuppression…
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