Articles tagged "HIV virus"

2019 American Transplant Congress
HIV Resistance among HOPE Donor Referrals
B. Barnaba¹, W. Werbel¹, O. Kusemiju¹, C. Kirby¹, Y. Eby¹, R. Fernandez¹, J. Miller¹, A. Redd², D. Segev¹, A. Tobian¹, C. Durand¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²National Institute of Allergy and Infectious Diseases, Bethesda, MD
*Purpose: After success in South Africa, HIV+ deceased donor (HIV D+) organs can now be used for transplant to HIV+ recipients in the US under…
2019 American Transplant Congress
Patterns Of Anti-retroviral Use Among U.s. Liver Transplant Candidates With Hiv
A. A. Shaffer¹, A. G. Thomas², D. L. Segev³
¹Johns Hopkins University, Baltimore, MD, ²Epidemiology, University of North Carolina, Chapel Hill, NC, ³Surgery & Epidemiology, Johns Hopkins University, Baltimore, MD
*Purpose: There is a high burden of liver disease among HIV-infected (HIV+) individuals, and the class of antiretroviral therapy (ART) used for their treatment may…
2019 American Transplant Congress
HOPE Act Deceased Donors Referrals: Barriers to Donation
O. Kusemiju, C. Durand, B. Doby, M. Bowring, B. Barnaba, W. Werbel, D. Brown, A. Tobian, S. Seaman, D. Ostrander, D. Segev
Johns Hopkins University, Baltimore, MD
*Purpose: HIV+ deceased donors (D+) represent a unique resource for HIV+ recipients but HIV D+ may have medical contraindications to donation or lower authorization rates.…
2019 American Transplant Congress
Impact of Protease Inhibitor-Based Anti-Retroviral Therapy on Tacrolimus Intrapatient Variability in HIV+ Kidney Transplant Recipients
M. H. Cooper, I. E. Dunne, S. A. Kuten, A. E. Cantwell, E. A. Graviss, D. T. Nguyen, M. J. Hobeika, A. O. Gaber
Houston Methodist Hospital, Houston, TX
*Purpose: High tacrolimus (FK) intra-patient variability (IPV) has been associated with inferior outcomes in solid organ transplantation. HIV+ transplant recipients have been shown to experience…
2019 American Transplant Congress
Effect of Induction Therapy on Absolute CD4 Count and CD4 Percentage in HIV Positive Kidney Transplant Recipients
S. A. Kuten¹, I. E. Dunne¹, A. E. Cantwell¹, M. J. Hobeika², S. G. Yi², W. Musick¹, R. J. Knight², A. O. Gaber²
¹Pharmacy, Houston Methodist Hospital, Houston, TX, ²Surgery, Houston Methodist Hospital, Houston, TX
*Purpose: Anti-thymocyte globulin (ATG) induction causes profound and long-lasting lymphocyte depletion, with CD4+ reconstitution lagging behind other subsets. While absolute CD4 count is the preferred…
2019 American Transplant Congress
Kidney Biopsies In Hiv-negative To Hiv-positive Kidney Transplants – An Institutional Experience
V. Walavalkar¹, A. Zarinsefat², A. Urisman¹, D. Dobi¹, J. Vasquez³, P. Stock², Z. Laszik¹
¹Pathology, UCSF Medical Center, San Francisco, CA, ²Transplant Surgery, UCSF Medical Center, San Francisco, CA, ³Medicine, UCSF Medical Center, San Francisco, CA
*Purpose: Increased life expectancy in HIV+ patients has resulted in an increase in CKD leading to ESRD; and therefore renal transplantation in these individuals is…
2019 American Transplant Congress
National Landscape of Hope Act Transplant Candidates and Recipients in the United States
A. R. Wilk¹, R. Hunter², M. A. McBride², D. K. Klassen²
¹Research, United Network for Organ Sharing, Richmond, VA, ²United Network for Organ Sharing, Richmond, VA
*Purpose: The HIV Organ Policy Equity (HOPE) Act, enacted on 11/21/13, allows for the transplantation of organs from HIV+ donors into HIV+ recipients in the…
2019 American Transplant Congress
Analysis Of Public Health Service Increased Risk Donors Shows No Viral Transmission In Liver Transplant Recipients And Similar Graft / Patient Survival When Compared To Non-increased Risk Donors
A. Amin, T. Ito, D. Ng, R. McMillan, J. DiNorcia, V. Agopian, F. Kaldas, H. Yersiz, R. Busuttil, D. Farmer
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Public Health Service increased risk donors (PHS-IRD) are underutilized in liver transplant (LT) due to concern for transmission of viral (HBV, HCV, and HIV)…
2018 American Transplant Congress
Waitlist Outcomes and Access to Liver Transplantation for HIV+ Candidates
A. Shaffer,¹ A. Thomas,¹ A. Massie,¹ S. Gustafson,² J. Snyder,² B. Shelton,³ R. Reed,³ J. Locke,³ D. Segev,^1,2 C. Durand.¹
¹JHU, Baltimore; ²SRTR, Minneapolis; ³UAB, Birmingham.
Liver disease is a leading cause of death for HIV+ individuals, and the number of HIV+ liver transplant recipients is increasing. However, since UNOS does…
2018 American Transplant Congress
Outcomes after HIV+ Liver Transplant: A HOPE in Action Study
C. Durand,¹ M. Bowring,¹ A. Tobian,^1,3 D. Brown,¹ A. Cameron,¹ S. Ottman,¹ K. Oshima,¹ D. Ostrander,¹ A. Redd,¹ S. Huprikar,² B. Haydel,² S. Lerner,² S. Florman,² S. Chandran,⁶ A. Chao,⁶ V. Kirchner,⁷ T. Pruett,⁷ A. Massie,¹ D. Segev.¹
¹JHU, Baltimore; ²Mount Sinai, New York; ³NIH, Bethesda; ⁴UCSF, San Francisco; ⁵UMN, Minneapolis.
The HOPE in Action Pilot Trial (NCT02602262) is assessing the safety and feasibility of HIV+ deceased donor (D+) kidney and liver transplantation for HIV+ recipients…

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