Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall 4EF
The annual number of HIV+ liver transplant (LT) recipients has increased >10-fold since 2002. However, candidate HIV-status is not collected by UNOS, and the national landscape of the HIV+ LT waitlist is not well characterized.
METHODS: We identified HIV+ candidates using SRTR (2002-2012) linked to pharmacy claims (covering 65% of the LT waitlist) and compared demographic and health characteristics of HIV+ vs. HIV- candidates using rank-sum and chi-squared tests.
RESULTS: We identified 581 HIV+ LT candidates, and the number listed increased over time (Figure1). The proportion of HIV+ LT candidates ranged from 0-2.5% by OPO (Figure2). HIV+ candidates were younger, more likely to be black, male, willing to accept HCV+ donors, and have public insurance, and less likely to be obese (vs. HIV-). Hepatitis C was the leading cause of liver disease in both groups, but was more frequent in HIV+ candidates (51.5% vs. 31.4%) (Table1).
CONCLUSION: HIV+ LT candidates are a growing, understudied population with a larger burden of hepatitis C than HIV- candidates. Given the differences between HIV+ and HIV- candidates, future studies should address the role of HIV in waitlist outcomes.
|Table 1. Demographic and health characteristics for HIV+ vs. HIV- liver transplant candidates.|
|Characteristic||HIV+ (n=581)||HIV- (n=71,793)||p-value|
|Age at listing, Median (IQR)||51 (46-55)||55 (49-60)||<0.001|
|Willing to accept HCV+ donor||58.7||45.7||<0.001|
CITATION INFORMATION: Shaffer A., Thomas A., Massie A., Gustafson S., Snyder J., Shelton B., Reed R., Locke J., Segev D., Durand C. National Landscape of HIV+ Liver Transplant Candidates Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:Shaffer A, Thomas A, Massie A, Gustafson S, Snyder J, Shelton B, Reed R, Locke J, Segev D, Durand C. National Landscape of HIV+ Liver Transplant Candidates [abstract]. https://atcmeetingabstracts.com/abstract/national-landscape-of-hiv-liver-transplant-candidates/. Accessed June 23, 2021.
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