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American Transplant Congress abstracts

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Articles tagged "Histology"

  • 2019 American Transplant Congress

    First UK Experience of the Molecular Microscope (MMDX™) in the Kidney Transplant Clinic

    C. Lawrence1, S. Thiru2, A. Manoj1, S. Fluck1

    1Renal Medicine, The Lister Hospital, Stevenage, United Kingdom, 2Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom

    *Purpose: Molecular diagnostic methods are now included in the Banff classification of kidney transplant pathology. Traditional histopathology may be limited by intra/inter pathologist variation. The…
  • 2019 American Transplant Congress

    Role of Kidney Biopsy in Simultaneous Heart-Kidney Transplantation

    P. B. Shah1, M. A. Josephson1, K. Henriksen2, A. Chang2

    1Nephrology, University of Chicago Medicine, Chicago, IL, 2Pathology, University of Chicago Medicine, Chicago, IL

    *Purpose: Simultaneous heart-kidney (SHK) transplantation has superior post-transplant survival compared to heart transplantation alone in end-stage heart failure patients who have dialysis dependent or non-dialysis…
  • 2018 American Transplant Congress

    A Novel Preservation Solution for Lung That Improves Cell Viability and Tissue Architecture

    J. Friedman,1 M. Samamrco,1 L. Marrero,1 B. Bunnell,1 D. Spyropoulos.2

    1Tulane University, New Orleans; 2MUSC, Charleston.

    Backgroud: Only 20% of donor lungs are used for transplant and 10 y survival of recipients is low. Many patients die within 30 d of…
  • 2018 American Transplant Congress

    An Integrative Approach for the Assessment of Peritubular Capillaritis Extent and Score in Microvascular Inflammation – Association with Transplant Glomerulopathy and Graft Loss

    N. Kozakowski,1 H. Herkner,2 F. Eskandary,3 M. Eder,3 W. Winnicki,3 G. Bond,3 Ž. Kikić.3

    1Department of Pathology, Medical University of Vienna, Vienna, Austria; 2Department of Emergency Medicine, Medical University of Vienna, Vienna, Austria; 3Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.

    Background:Banff Classification accepts two histomorphological features as surrogates of HLA Antibody-Antigen interaction on renal endothelium: C4d staining and microvascular inflammation scores (MVI sum score:ptc+g≥2) which…
  • 2018 American Transplant Congress

    Transplant Tourism and Invasive Fungal Infection

    F. Al Ismaili,1 A. Metry,3 M. Al Riyami,5 F. Khamis,6 F. Shaheen,7 A. Hola,4 I. Al Salmi.2

    1The Renal Medicine, The Royal Hospital, Muscat, Oman; 2The Renal Medicine, The Royal Hospital, Muscat, Oman; 3The Renal Medicine, The Royal Hospital, Muscat, Oman; 4Histopathology, SQUH, Muscat, Oman; 5Infectious Diseases, The Royal Hospital, Muscat, Oman; 6SCOT, SCOT, RIyadh, Saudi Arabia; 7The Renal Medicine, The Royal Hospital, Muscat, Oman; 8The Renal Medicine, The Royal Hospital, Muscat, Oman.

    Deceased and live-related Renal transplant (RTX) are widespread approved methods throughout the world. In-addition, commercial-RTX has gained an access at certain places driven by financial…
  • 2018 American Transplant Congress

    Diffuse Optical Non-Invasive Organ Risk (DONOR) Indexing Using Diffuse Reflectance Spectroscopy for Pre-Transplant Evaluation

    H. Borron,1 D. Piao,2 A. Hawxby,3 H. Wright,3 E. Rubin.4

    1College of Medicine, University of Oklahoma, Oklahoma City, OK; 2School of Electrical and Computer Engineering, Oklahoma State University, Stillwater, OK; 3Oklahoma Transplant Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK; 4Pathology, University of Oklahoma, Oklahoma City, OK.

    Purpose: Due to large transplant waitlists, a rapid, non-invasive method to evaluate organ quality for transplantation is needed. Diffuse optical spectroscopy (DOSi) is an optical…
  • 2018 American Transplant Congress

    Renal Allograft Molecular Pathways Associated with Tolerance Induction in Renal Transplantation

    L. Gallon,1 J. Mathew,1 S. Bontha,2 C. Dumur,2 P. Dalal,1 L. Nadimpalli,1 D. Maluf,2 A. Shetty,1 S. Ildstad,3 J. Leventhal,1 V. Mas.2

    1Department of Medicine-Nephrology, Northwestern University, Chicago, IL; 2Department of Surgery, University of Virginia, Charlottesville, VA; 3Departments of Surgery, Physiology and Immunology, University of Louisville, Louisville, KY.

    Background: Chronic exposure to immunosuppressive agents for organ transplant results in graft nephrotoxicity, infections and malignancies We have established durable immune tolerance in mismatched related…
  • 2018 American Transplant Congress

    Functional Reconstruction of Urogenital Tissue Defects Using VCA: A Novel Microsurgical Penis Transplant Model and Clinical & Histological Rejection Classification

    S. Fidder,1,4 G. Furtmüller,1 B. Simons,2 B. Kern,1 D. Lough,1 B. Oh,1 M. Chicco,1 C. Brayton,3 W. Lee,1 D. Cooney,1 R. Redett,1 G. Brandacher.1

    1Dept of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore; 2Dept of Urology, JHU SOM, Baltimore; 3Dept of Molecular & Comparative Pathobiology, JHU SOM, Baltimore; 4Plastic and Reconstructive Surgery, Erasmus University Medical Center, Rotterdam, Netherlands.

    Background: Defects of male urogenital structures subsequent to major trauma are associated with severely reduced function and quality-of-life. As of recent, penis transplantation represents an…
  • 2018 American Transplant Congress

    Scoring Transplant Glomerulopathy Using Morphometry: Correlation with Banff Criteria

    M. Morales, A. Denic, W. Park, B. Smith, M. Alexander, M. Stegall.

    William J.von Liebig Transplant Center, Mayo Clinic, Rochester, MN.

    Background: Transplant glomerulopathy (TG) is a prognostic marker for graft survival. Still, scoring TG using the Banff cg-score remains a challenge and no assessments in…
  • 2018 American Transplant Congress

    Pre-Existing Allograft Diabetic Nephropathy from Diabetic Donor is Reversible after Kidney Transplantation in Non-Diabetic Recipient

    K. Hotta,1 D. Iwami,1 H. Harada,2 Y. Fukasawa,2 H. Okada,1 H. Higuchi,1 T. Hirose,2 N. Fukuzawa,2 N. Shinohara.1

    1Hokkaido University Hospital, Sapporo, Japan; 2Sapporo City General Hospital, Sapporo, Japan.

    【Introduction】The shortage of kidney donor has limited the treatment of patients with end-stage kidney disease. To use diabetic donor with normal renal function is would…
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