2022 American Transplant Congress
Estimating the Effect of Increased Donor Heart Ischemic Time on Post-Transplant Survival Using Instrumental Variables
*Purpose: Isolate the impact of organ ischemic time on post-transplant survival using the recent change in heart allocation policy as a natural experiment.*Methods: We examined…2022 American Transplant Congress
Outcome of Solid Organ Transplantation in Candidates with Intellectual Disability: A Systematic Review
Erasmus MC, Rotterdam, Netherlands
*Purpose: The allocation of organs comes with an ethical discussion in patients with intellectual disability. Historically, intellectual disability was considered a relative contra-indication for organ…2022 American Transplant Congress
The Role of Geography in Adult Heart Allocation Over the Last 5 Years
*Purpose: In the last 5 years two policies have impacted the role of geography in adult heart allocation including the 2018 adult heart policy which…2022 American Transplant Congress
Cd47 Expression on Transplanted Human Neonatal Mesenchymal Stem Cells Inhibits Phagocytosis in Rat Myocardial Infarction Model
Lurie Childrens Hospital, Chicago, IL
*Purpose: Immune rejection of transplanted stem/progenitor cells is a major stumbling block in designing effective therapy for myocardial infarction (MI). Human neonatal mesenchymal stem cells…2022 American Transplant Congress
Correlating Histology, Immunohistochemical, & Serologic Data in Heart Transplant Recipients: Implications for Molecular Diagnostic Assays
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The ISHLT classification of rejection in heart allograft biopsies is independent of DSA status. There is only limited data on the prevalence of DSA…2022 American Transplant Congress
Significant Reduction of Troponin I Elaboration After Ischemia Minimization in the First Hour of Ex Vivo Xeno Heart Perfusion
*Purpose: Previous studies showed that ischemia minimization (IM), accomplished by perfusing the heart xenograft during storage, prevents ‘initial cardiac xenograft dysfunction’ (ICXD) and enables prolonged…2022 American Transplant Congress
Equity in Access to Deceased Donor Transplant for Candidates on the Heart Waitlist
*Purpose: Transplantation is often the gold standard therapy for those with organ failure, but limited supply prevents all patients from accessing this treatment. The Organ…2022 American Transplant Congress
Association Between Allograft Gene Expression and Acute Cellular Rejection Grade in Heart Transplant Recipients
*Purpose: Endomyocardial biopsy (EMB) remains the gold standard in acute rejection (AR) surveillance in heart transplantation (HT) despite interpretation subjectivity and low concordance rates between…2022 American Transplant Congress
The Use of Donor-Derived Cell-Free DNA in Female and Male Heart Transplant Recipients: A Sex-Specific Analysis of the Surveillance Heartcare Outcomes Registry
*Purpose: To investigate sex-specific donor-derived cell-free DNA AlloSure (AS) levels during allograft quiescence and rejection after heart transplantation.*Methods: Sex-stratified data were obtained from the Surveillance…2022 American Transplant Congress
Impaired Left Ventricular Global Longitudinal Strain: Clinical Presentation and Outcomes in Liver Transplantation Recipients without Arrhythmia or Structural Heart Disease
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Assess the prevalence and characteristics of patients without arrhythmia or structural heart disease (SHD) but with impaired pre-transplant left ventricular global longitudinal strain (GLS)…
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