2022 American Transplant Congress
Results of Heart Transplantation from Donation After Circulatory Death (DCD) Donors Using Thoraco-Abdominal Normothermic Regional Perfusion (TA-NRP) Compared to Donation from Donation After Brain Death (DBD) Are Similar at One Year
*Purpose: In the U.S., interest in heart transplantation organ donation from DCD is increasing. Several different approaches are being considered. We present our institutional experience…2022 American Transplant Congress
Cardiovascular Assessment After Kidney Transplantation in Children and Adolescents
The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: End-stage renal disease is often accompanied by cardiovascular events, and cardiovascular events still exist after kidney transplantation. Cardiovascular disease is the main cause of…2022 American Transplant Congress
Donor Derived Cell-Free DNA Median and Distribution in Pediatric Heart Transplant Patients
1CareDx, South San Francisco, CA, 2Children's Hosp of Pittsburgh, Pittsburgh, PA
*Purpose: The utilization of endomyocardial biopsy (EMB) in the post-transplant surveillance of pediatric heart transplant (pHT) recipients can be challenging for a myriad of reasons;…2022 American Transplant Congress
Early Experience with Varicella Vaccination in Pediatric Heart Transplant Recipients
The Hospital of Sick Children, Toronto, ON, Canada
*Purpose: International consensus guidelines to vaccinate children after transplant with varicella (VZV) vaccine exclude heart recipients due to insufficient evidence for safety, seroconversion rate, and…2022 American Transplant Congress
Regulatory Gene Pathways Are Upregulated in Heart Transplant Biopsies with Quilty Lesions
Pathology, UTSW Medical Ctr, Dallas, TX
*Purpose: Quilty lesions (QL) are commonly sub-endocardial lymphoid aggregates found in biopsies from heart transplants. Their appearance and presence in the cardiac tissue is still…2022 American Transplant Congress
Changes in Diastolic Function and Cardiac Geometry After Pediatric Kidney Transplant: A Longitudinal Study
*Purpose: Kidney transplant recipients are at increased risk for cardiovascular disease but systolic function is often preserved and may not reveal cardiac dysfunction until it…2022 American Transplant Congress
Marginal Zone B Cells Support T Cell Reconstitution Following ATG Lymphoablation in Heart Allograft Recipients.
Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH
*Purpose: Lymphoablation with anti-thymocyte globulin (ATG) is a common therapy in solid organ transplantation. However homeostatic proliferation of pre-existing memory T cells undermines the graft-prolonging…2022 American Transplant Congress
The Gut Microbiome in the Critical Care Setting Post-Heart Transplantation
*Purpose: Given its potential impact on immune activation and systemic inflammation, we aim to investigate gut microbiome compositions and metabolites during critical illness in the…2022 American Transplant Congress
Resource Expenditure in the Evaluation of Older Donors for Heart Transplant: An Impediment to Donor Pool Expansion?
*Purpose: Using older donors for heart transplant (HT) could alleviate donor scarcity but the resource implications of this strategy - and whether evaluation of older…2022 American Transplant Congress
cDC1-Mediated Prolongation of Cardiac Allograft Survival and Alloantigen Induced Transcriptional Programming
Pathology, Northwestern Feinberg School of Medicine, Chicago, IL
*Purpose: Heart transplantation is currently the only treatment for advanced stage heart failure. While patient survival after transplantation has improved acutely, the same cannot be…
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