Articles tagged "Heart"

2019 American Transplant Congress
Low Frequency Of Canonical Human Leukocyte Antigen Alloimmunization In Heart Transplantation Candidates With Ventricular Assist Devices
G. K. Mahowald¹, S. L. Saidman¹, G. Lewis², V. Pattanayak¹
¹Pathology, Massachusetts General Hospital, Boston, MA, ²Cardiology, Massachusetts General Hospital, Boston, MA
*Purpose: Screening for anti-HLA antibodies in heart transplantation candidates is complicated by transfusions as well as by the presence of ventricular assist devices (VADs), which…
2019 American Transplant Congress
Outcome Of Left Main Stenting After Heart Transplantation
S. Dimbil, J. Patel, B. Azarbal, M. Kittleson, R. Levine, D. H. Chang, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Cardiac allograft vasculopathy (CAV) is one of the major factors limiting long-term survival after HTx. The use of angioplasty and drug-eluting stents is common…
2019 American Transplant Congress
Perioperative Cardiac Xenograft Dysfunction after Orthotopic Transplantation is for Real
M. Mohiuddin¹, A. Singh¹, L. DiChiacchio¹, D. Kaczorowski¹, B. Lewis¹, T. Zhang¹, F. Sentz¹, I. Tatarov¹, D. Parsell¹, P. Odonkor¹, E. Strauss¹, B. Williams¹, K. Deatrick¹, D. Ayares², B. Griffith¹, S. Bartlett¹
¹Department of Surgery, University of Maryland Baltimore, Baltimore, MD, ²Revivicor, Inc, Blacksburg, VA
*Purpose: After successful prolongation of cardiac xenograft survival in a heterotopic position, the next step is to evaluate genetically engineered (GE) pig hearts for their…
2019 American Transplant Congress
Myeloid AXL Promotes Cardiac Allograft Vasculopathy
K. E. Glinton¹, X. Yeap¹, Z. J. Zhang², X. Luo³, E. B. Thorp¹
¹Pathology, FCVRRI, Northwestern University - Feinberg School of Medicine, Chicago, IL, ²Surgery, Northwestern University - Feinberg School of Medicine, Chicago, IL, ³Duke Transplant Center, Duke University School of Medicine, Durham, NC
*Purpose: Cardiac Allograft Vasculopathy (CAV) is a significant contributor to long term transplant rejection, despite advances in immunotherapy. Reactivity to alloantigen presentation may occur by…
2019 American Transplant Congress
First Experience For Cold Storage Of Donor Hearts With Paragonix SherpaPak
L. Stastny¹, M. Kofler¹, D. Höfer¹, G. Pölzl², R. Breitkopf³, M. Grimm¹, H. Antretter¹, J. Dumfarth¹
¹Cardiac Surgery, Medical University Innsbruck, Innsbruck, Austria, ²Internal Medicine, Medical University Innsbruck, Innsbruck, Austria, ³Intensive Care Unit, Medical University Innsbruck, Innsbruck, Austria
*Purpose: Preservation of donor organs is a crucial component for the maintenance of viability after explantation. The current standard for transporting a donor organ includes…
2019 American Transplant Congress
What Are You Smoking? The Impact of Donor Drug Use on Long Term Survival Post-Transplant
D. A. Baran¹, A. Long¹, J. T. Lansinger², H. Copeland³, J. M. Herre¹, W. Old¹, G. Zeevi¹, C. Barreiro¹, C. Kemp¹, B. H. Smith¹, K. Stelling¹, A. Ingemi¹, P. Bourassa¹, J. Philpott¹
¹Sentara Heart Hospital, Norfolk, VA, ²Eastern Virginia Medical School, Norfolk, VA, ³Division of Cardiothoracic Surgery, University of Mississippi Medical Center, Jackson, MS
*Purpose: Drug use is a common aspect in the history of heart transplant donors. Whether prior or current drug use is associated with inferior post…
2019 American Transplant Congress
The Use Of First-year Intravascular Ultrasound In The Tacrolimus Era In Heart Transplantation
S. Dimbil¹, M. Kittleson¹, J. Patel¹, D. Geft¹, R. Cheng¹, R. Levine¹, T. Sato¹, L. Czer¹, R. Zabner², P. Zakowski², J. A. Kobashigawa¹, B. Azarbal¹
¹Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, ²Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Cytomegalovirus (CMV) has been documented as a risk factor for the development of cardiac allograft vasculopathy (CAV) after heart transplantation (HTx). It has not…
2019 American Transplant Congress
Donors and Drugs: How Often Do They Mix? Utilization of Donors Based on Toxicology Findings
J. T. Lansinger¹, A. Long¹, C. Barreiro², J. M. Herre², H. Copeland³, W. Old², G. Zeevi², C. D. Kemp², J. M. Philpott², K. Stelling², A. Ingemi², B. H. Smith², P. Bourassa², D. A. Baran²
¹Eastern Virginia Medical School, Norfolk, VA, ²Sentara Heart Hospital, Norfolk, VA, ³Division of Cardiothoracic Surgery, University of Mississippi Medical Center, Jackson, MS
*Purpose: Despite an increasing number of patients waiting for heart transplantation, the growth of transplant volume has risen slowly. The opioid crisis has resulted in…
2019 American Transplant Congress
What is the Post-Heart Transplant Risk of Infectious Complications from Pre-Transplant Desensitization Therapy?
E. Kransdorf, J. Patel, S. Dimbil, R. Levine, D. H. Chang, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Sensitization or the detection of circulating antibodies in heart transplant candidates appears to be increasing due to the growing use of mechanical circulatory support…
2019 American Transplant Congress
How Do We Choose? Predicting Utilization Of Cardiac Donors And The Effect Of Era
D. A. Baran¹, J. T. Lansinger², A. Long², J. Philpott³, H. Copeland⁴, W. Old³, G. Zeevi³, C. Barreiro³, C. Kemp³, B. H. Smith³, K. Stelling³, A. Ingemi³, P. Bourassa³, J. M. Herre³
¹Sentara Heart Hospital, Virginia Beach, VA, ²Eastern Virginia Medical School, Norfolk, VA, ³Sentara Heart Hospital, Norfolk, VA, ⁴University of Mississippi Medical Center, Jackson, MS
*Purpose: The number of patients on the heart transplant waitlist continues to rise. However, the rate of organ acceptance is only about 1/3 of all…