ATC Abstracts

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Articles tagged "Graft survival"

  • 2016 American Transplant Congress

    Influence of Pancreas Import and Cold Ischemia on Outcomes Following Pancreas Transplantation.

    M. Khan,1 H. El-Hennawy,1 J. Rogers,1 A. Farney,1 G. Orlando,1 A. Reeves-Daniel,2 A. Palanisamy,2 R. Stratta.1

    1Surgery, Wake Forest, Winston-Salem, NC; 2Internal Medicine, Wake Forest, Winston-Salem, NC.

    Proposed changes in pancreas transplant (PT) allocation may improve organ sharing but increase cold ischemia time (CIT). Methods: We performed a single center, retrospective study…
  • 2016 American Transplant Congress

    Evaluating Delayed Graft Function After Kidney Transplantation as a Potential Surrogate Outcome.

    S. Cramm, X. Luo, A. Massie, D. Segev.

    Department of Surgery, Johns Hopkins, Baltimore, MD.

    Background: Recent work demonstrates significant inter-center heterogeneity in delayed graft function (DGF) rates after kidney transplantation, calling into question the value of a metric based…
  • 2016 American Transplant Congress

    Donor Sharpin Expression Modulates TNFα Mediated Inflammation and Cardiac Allograft Rejection in Mice.

    R. Ang,1 P. Heeger,2 A. Ting.1

    1Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, NY; 2Center for Translational Transplant Research, Icahn School of Medicine at Mount Sinai, New York City, NY.

    Increased systemic TNFα levels correlate with transplant rejection and severity of GVHD, and TNFα blockade can prolong graft survival and reduce severity of GVHD. These…
  • 2016 American Transplant Congress

    Assessment of Postoperative Glycemic Control in Orthotopic Heart Transplant Recipients.

    J. Glick Frasiolas, J. Matthew, D. Tsapepas.

    NewYork-Presbyterian Hospital, Columbia University, New York.

    Hyperglycemia may occur after solid organ transplantation because of stress, immunosuppressants, and diabetes mellitus. Glycemic control has been shown to decrease morbidity and mortality in…
  • 2016 American Transplant Congress

    Outcomes with the Use of Pediatric Donor Livers in Adult Recipients: Review of the UNOS Database.

    K. Croome, D. Lee, J. Burns, J. Nguyen, D. Perry, C. Taner.

    Transplant, Mayo Clinic Florida, Jacksonville, FL.

    Background: While there is an agreement that pediatric donor (PD) livers should ideally be used for pediatric recipients, there remain some situations where these livers…
  • 2016 American Transplant Congress

    Patients with ESRD Due to Diabetes Have Higher Variability of Their Tacrolimus Levels and Worse Outcomes.

    D. Goodall, M. Willicombe, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.

    IntroductionNonadherence to immunosuppressants is associated with rejection and graft loss and nonadherence to antidiabetics is associated with poor glycaemic control leading to microvascular complications and…
  • 2016 American Transplant Congress

    Urinary Virome in Human Kidney Transplants Reveals Multiple Virus Subtypes with Distinct Genome Polymorphisms.

    R. Ranjan,1 A. Rani,1 H. McGee,1 D. Brennan,2 P. Finn,1 D. Perkins.1,3

    1Medicine, University of Illinois, Chicago, IL; 2Division of Renal Diseases, Washington University School of Medicine, St. Louis, MO; 3Surgery, University of Illinois, Chicago, IL.

    Recent studies have established that human urine has its own unique microbiome, but little is known about the virome. The human virome is the collection…
  • 2016 American Transplant Congress

    Fecal Microbiota Transplant Results in Durable Changes to Host Microbiota That Correlate with Allograft Outcome.

    C. Brinkman, L. Hittle, W. Fricke, E. Mongodin, J. Bromberg.

    CVID and IGS, University of Maryland School of Medicine, Baltimore, MD.

    Hypothesis: We previously presented highly significant differences in the bacterial community structures of human renal allograft recipients over time. Likewise, murine normal, colitic, and pregnant…
  • 2016 American Transplant Congress

    Machine Perfusion (MP) at 21[deg]C Simulates Hibernation Metabolic Pathways in a Non-Hibernator Mammal.

    B. Banan, S. Dobrowolski, G. Michalopoulos, P. Fontes.

    University of Pittsburgh, Pittsburgh.

    Background: Hibernation is a complex and multi stage process that leads to unique metabolic changes over an extended period of time. Regulatory genes and transcription…
  • 2016 American Transplant Congress

    The Oldest and Coldest in Kidney Paired Donation: Experience of the National Kidney Registry.

    N. Nassiri,1 L. Kwan,1 J. Sinacore,2 J. Veale.1

    1Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA; 2National Kidney Registry, Babylon, NY.

    OBJECTIVES: To evaluate renal allograft efficacy and survivability in elderly donors and prolonged cold ischemia time (CIT).METHODS: 1,402 living donor kidney transplants from 02/2008-06/2015 recorded…
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