ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2016 American Transplant Congress

    Antithymocyte Globulin (ATG) versus Anti-interleukin-2 Receptor (Anti-IL-2R) as Induction Therapy for Kidney Transplantation After a Nonrenal Transplant.

    H. Mai,1 K. Trébern-Launay,1 C. Legendre,2 M. Kessler,3 L. Rostaing,4 V. Garrigue,5 E. Morelon,6 S. Brouard,1 M. Giral,1 J.-P. Soulillou.1

    1Service de Néphrologie et Transplantation, INSERM UMR 1064, CHU de Nantes, Nantes, France; 2Hôpital Necker, Paris, France; 3CHU de Nancy, Nancy, France; 4CHU de Toulouse, Toulouse, France; 5CHU de Montpellier, Montpellier, France; 6CHU de Lyon, Lyon, France.

    Patients undergoing kidney transplant after a previous nonrenal organ transplant (NRT) present a small but emerging subpopulation of kidney transplant recipients. Little is known about…
  • 2016 American Transplant Congress

    Post-Transplant Monitoring of Donor-Specific Anti-HLA Antibodies and Their Characteristics Improves Risk Stratification of Kidney Allograft Loss.

    D. Viglietti,1 A. Loupy,2 C. Bentlejewski,3 C. Legendre,2 D. Glotz,1 A. Zeevi,3 C. Lefaucheur.1

    1Saint-Louis Hospital, Paris, France; 2Necker Hospital, Paris, France; 3University of Pittsburgh Medical Center, Pittsburgh.

    Circulating donor-specific anti-HLA antibodies (DSA) are associated with allograft failure in solid-organ transplantation. We investigated the pathogenic characteristics of DSA that may improve risk prediction…
  • 2016 American Transplant Congress

    Lessons Learned Transplanting High KDPI Kidneys Over a Decade: Improvements in Graft Survival Stem from Lower Rates of Early Graft Loss.

    S. Sanoff,1 K. Ravindra, D. Vikraman, U. Patel, D. Sudan, W. Irish.2

    1Duke University Medical Center, Durham, NC; 2CTI Clinical Trial and Consulting Services, Raleigh, NC.

    Purpose. The Kidney Donor Profile Index (KDPI) recently replaced SCD/ECD designations, to provide transplant centers a more precise estimate of predicted graft survival, with the…
  • 2016 American Transplant Congress

    Transitional B Cell T1/T2 Ratio Is a Prognostic Marker for Human Renal Allograft Deterioration.

    A. Cherukuri,1 D. Rothstein,1 R. Baker.2

    1UPMC, Pittsburgh; 2University of Leeds, Leeds, United Kingdom.

    Human transitional B cells (TrB) may play a significant role in auto and alloimmune disease. TrB express a high IL10:TNFα ratio and this fell with…
  • 2016 American Transplant Congress

    Incidence, Risk Factors, and Outcomes of Delayed Graft Function in Deceased Donor Kidney Transplantation in a Brazilian Center.

    A. Ribeiro,1 M. Helfer,2 O. Costa,2 A. Viccari,1 R. Manfro.1,2

    1Division of Nephrology, Renal Transplant Unit, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil; 2School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

    Background. A high incidence of delayed graft function (DGF), after deceased donor kidney transplantation, occurs in Brazil and the reasons for such finding have not…
  • 2016 American Transplant Congress

    Non-adherence to Appointments Is a Strong Predictor of Medication Non-Adherence and Outcomes in Kidney Transplant Recipients.

    M. Posadas Salas, R. Pullalarevu, M. Kamel, A. Chokkalingam, R. Browning, B. Kadri, M. Salazar, T. Srinivas, D. Taber.

    Medical University of South Carolina, Charleston, SC.

    Disparities in healthcare access and non-adherence are important aspects of transplantation that affect outcomes. This study aims to investigate the impact of non-adherence to laboratory…
  • 2016 American Transplant Congress

    Replicative Senescence and Arteriosclerosis After Kidney Transplantation.

    K. De Vusser,1 D. Martens,2 E. Lerut,3 D. Kuypers,1 T. Nawrot,2 M. Naesens.1

    1Department of Nephrology and Renal Transplantation, UZ Leuven, Leuven, Belgium; 2Department of Imaging and Pathology, KULeuven, Leuven, Belgium; 3Centre for Environmental Sciences, U Hasselt, Hasselt, Belgium.

    BackgroundReplicative senescence is associated with telomere shortening. In native kidneys, obtained prior to transplantation, we recently described and validated a significant association between shorter intrarenal…
  • 2016 American Transplant Congress

    Outcomes of Arterial and Venous Conduits for Vessel Reconstruction in Liver Transplantation.

    J. Tan,1 G. Oniscu.2

    1University of Edinburgh, Edinburgh, United Kingdom; 2Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

    Background: The use of hepatic artery (HA) and portal vein (PV) conduits is a recognised alternative technique in vessel reconstruction during liver transplantation. The hepatic…
  • 2016 American Transplant Congress

    Influence of Donor and Recipient CYP3A4, CYP3A5 and ABCB1 Genotypes on Outcomes in Liver Transplants.

    M. Debette-Gratien,1 J. Woillard,2 N. Picard,2 M. Sebbagh,4 D. Sautereau,5 V. Loustaud-Ratti,1 D. Samuel,3 P. Marquet.2

    1Hepatology, INSERM UMR 850, Univ Limoges, CHU Limoges, Limoges, France; 2Pharmacology and Toxicology, INSERM UMR 850, Univ Limoges, CHU Limoges, Limoges, France; 3Hepatology, INSERM U785, Centre hépatobiliaire, Villejuif, France; 4Hepatology, Centre Hépatobiliaire, Villejuif, France; 5Hepatology, CHU Limoges, Limoges, France.

    Liver transplantation is a life-saving technique for patients with end-stage liver disease. Pharmacogenetics is promising to explain a part of variability of calcineurin inhibitors efficacy…
  • 2016 American Transplant Congress

    A Retrospective Study of Simultaneous Bilateral Nephrectomies and Renal Transplantation in Recipients with Polycystic Kidney Disease.

    E. Grodstein, D. Kaufman.

    Department of Surgery, Division of Transplantation, University of Wisconsin, Madison, WI.

    Background: Many strategies regarding timing of native nephrectomies exist for patients with symptomatic polycystic kidney disease (PCKD). We hypothesize that the timing of bilateral nephrectomies…
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