2016 American Transplant Congress
Impact of Early Hospital Readmission Following Simultaneous Pancreas Kidney Transplantation.
Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.
BACKGROUND: Our group recently demonstrated that 54% of simultaneous pancreas kidney (SPK) recipients experience early hospital readmission (EHR). It is unknown whether EHR following SPK…2016 American Transplant Congress
Phenotype and Outcome of Antibody-Mediated Rejection Due to Pre-Existing and De Novo DSA in Kidney Recipients.
Antibody-mediated rejection (ABMR) presents with either pre-existing or de novo DSA. The aim of the study was to compare the two ABMR phenotypes and their…2016 American Transplant Congress
Periodical Peer Review of a Pancreas Transplant Programme: Can It Enhance Performance?
Introduction:In the UK, NHS Blood and Transplant (NHSBT), the national transplant regulatory body, monitors 30-day graft loss and patient mortality by CUmulative SUMmation methodology (CUSUM).…2016 American Transplant Congress
Late Outcome Surrogate Score (LOSS) for Kidney Allograft Failure.
Comprehensive Transplant Center, Northwestern University, Chicago, IL.
Background. Early outcomes following kidney transplant have steadily improved. Longer-term outcomes, while not the focus of regulatory oversight, are of vital importance. Clinical trials are…2016 American Transplant Congress
ESAT-6 Inhibits Donor-Specific Memory CD8+ T Cell Generation and Alloimmune Responses.
Inducing long-term transplant survival or tolerance without continuous global immunosuppression is a highly desired goal in organ transplantation because conventional immunosuppressive drugs usually cause severe…2016 American Transplant Congress
Donor AKI Does Not Adversely Affect the Outcome Following DCD Kidney Transplant.
BackgroundTransplanting kidneys from donation after cardiac death (DCD) donors has been associated with good outcome, but the impact of added donor AKI on the outcome…2016 American Transplant Congress
Deceased Donor Kidney Transplantation in the Setting of Positive Donor-Specific Antibodies.
1Johns Hopkins University, Baltimore; 2University of Michigan, Ann Arbor.
Recent changes to the kidney allocation system favor highly sensitized transplant candidates, resulting in these patients receiving more offers for deceased donor (DD) kidneys. Despite…2016 American Transplant Congress
Outcomes of Second Kidney Transplantation Compared Primary Transplantation According to Donor Specific Antibody.
Background:Re-transplantation is associated with an improved overall survival of patients with a failed renal allograft. Some studies showed the outcomes of retransplantation are than those…2016 American Transplant Congress
Genetic TIM-4 Deletion Promotes Immunoregulatory Tissue-Resident Macrophage Survival and Lowers the Barrier to Cardiac Allograft Tolerance.
We report that the CD169+TIM-4+ tissue-resident macrophage (TRM) subset is the dominant tissue-resident leukocyte in skin, heart, and pancreas from C57BL/6 mice and skin and…2016 American Transplant Congress
Prolongation of Graft Survival by Anti-TIM1 Is Specifically Mediated by IL-10+ Bregs and Is Not Dependent on IL-35 or Plasma Cell Differentiation.
In B cell-deficient mice, prolonged islet allograft survival (GS) mediated by anti-TIM1 depends on transfer of IL-10 competent B cells. However, such regulatory B cells…
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