ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Incidence, Risk Factors, and Outcomes of Delayed Graft Function in Deceased Donor Kidney Transplantation in a Brazilian Center.

A. Ribeiro,1 M. Helfer,2 O. Costa,2 A. Viccari,1 R. Manfro.1,2

1Division of Nephrology, Renal Transplant Unit, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
2School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Meeting: 2016 American Transplant Congress

Abstract number: A268

Keywords: Donors, Graft survival, Kidney transplantation, marginal, Renal function

Session Information

Date: Saturday, June 11, 2016

Session Name: Poster Session A: Poster Session III: Kidney Complications-Other

Session Time: 5:30pm-7:30pm

 Presentation Time: 5:30pm-7:30pm

Location: Halls C&D

Related Abstracts
  • Surgical Anastomosis Time and Its Effect on Delayed Graft Function and Early Outcomes in Deceased Donor Kidney Transplantation
  • The Impact of Early Acute Rejection and Delayed Graft Function on Graft Outcomes at Six Months in Adult Deceased Donor Kidney Recipients.

Background. A high incidence of delayed graft function (DGF), after deceased donor kidney transplantation, occurs in Brazil and the reasons for such finding have not been adequately studied.

Methods. We performed a retrospective single center cohort study including 517 deceased donor kidney transplant recipients. Risk factors for DGF were analyzed and correlated with graft outcomes. A multivariable analysis (Poisson regression) was used to identify independent risk factors and patient and graft survival were assessed using Kaplan-Meier curves.

Results. The incidence of DGF was 65.6% (339 cases). In the final multivariate analysis model DGF is significantly associated with donor final serum creatinine, donor age, cold ischemia time, use of antibody induction therapy and diabetes mellitus. The relative risks and 95% confidence intervals were: donor final serum creatinine: 1.088 (1.018 – 1.162); donor age: 1.007 (1.002 – 1.012), cold ischemia time: 1.020 (1.006 – 1.034), use of antibody induction therapy: 1.787 (1.103 – 2.896) and diabetes mellitus as cause o recipient kidney disease: 1.162 (1.002 – 1.347). The occurrence of DGF was also associated with longer length of hospital stay (31.7 ± 20.9 versus 18.5 ± 12.9 days; P = 0.01), higher incidence of acute treated (35.9 versus 20.0%; P < 0.01) and BANFF 1A or higher acute rejection (24.5 versus 14.7%; P = 0.017), lower graft function at 3, 6 and 12 months after transplantation and worse death censored graft survival at 1 year (94.0% versus 96.6%; P < 0.038) and at 5 years (84,6 versus 95%, p=0,038). No differences were found in patient survival.

Conclusion. In the present cohort DGF was associated with higher donor age, final serum creatinine, cold ischemia time, diabetes mellitus and need for antibody induction therapy. Most importantly, DGF was associated with worse outcomes in terms of graft function and survival.

CITATION INFORMATION: Ribeiro A, Helfer M, Costa O, Viccari A, Manfro R. Incidence, Risk Factors, and Outcomes of Delayed Graft Function in Deceased Donor Kidney Transplantation in a Brazilian Center. Am J Transplant. 2016;16 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Ribeiro A, Helfer M, Costa O, Viccari A, Manfro R. Incidence, Risk Factors, and Outcomes of Delayed Graft Function in Deceased Donor Kidney Transplantation in a Brazilian Center. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/incidence-risk-factors-and-outcomes-of-delayed-graft-function-in-deceased-donor-kidney-transplantation-in-a-brazilian-center/. Accessed March 7, 2021.

« Back to 2016 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Home
  • Search
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.