ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2016 American Transplant Congress

    Post-Transplantation Hypomagnesemia as a Predictor of Survival Among the Kidney Transplant Population.

    T. Hod, B. Patibandla, A. Chandraker.

    Transplant Research Center, Brigham and women's hospital, Boston, MA.

    We have previously shown a robust relationship between low magnesium in the first year post-transplant and better long-term kidney allograft function. Given this somewhat counterintuitive…
  • 2016 American Transplant Congress

    NAD+ Promotes Allograft Survival Independently of CD4+CD25+Foxp3+ Regulatory T Cells.

    A. Elkhal, H. Rodriguez Cetina Biefer, H. Uehara, M. Quante, M. Seyda, J. Schuitenmaker, S. Tullius, A. Elkhal.

    Surgery, Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

    CD4+CD25+Foxp3+ regulatory T cells (Tregs) play a central role in the maintenance of immune tolerance and T cell homeostasis. It is known that Tregs promote…
  • 2016 American Transplant Congress

    Composite Score to Define the Risk of Allograft Loss After Standard-of-Care Treatment of Antibody-Mediated Rejection in Kidney Transplantation.

    D. Viglietti,1 A. Loupy,2 J. Duong Van Huyen,2 J. Verine,1 A. Zeevi,3 C. Legendre,2 D. Glotz,1 C. Lefaucheur.1

    1Saint-Louis Hospital, Paris, France; 2Necker Hospital, Paris, France; 3University of Pittsburgh Medical Center, Pittsburgh.

    The development of a reliable surrogate endpoint for allograft survival after AMR treatment is a current unmet need in clinical transplantation (FDA AMR Workshop). We…
  • 2016 American Transplant Congress

    Detection of Venous Thrombi by Microdialysis Catheters and Angiographic Guided Thrombus Extraction in Two Solitary Pancreas Transplants.

    G. Kjosen,1 R. Horneland,2 E. Aandahl,2 O. Oyen,2 T. Tonnessen,1,3 H. Hakon.1

    1Anesthesiology, Oslo University Hospital, Oslo, Norway; 2Transplantation Surgery, Oslo University Hospital, Oslo, Norway; 3Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

    Introduction: The complication rate after pancreas transplantation (PTx) is very high, with venous thrombosis being the most commonly occurring complication that leads to early graft…
  • 2016 American Transplant Congress

    Endoscopic Polydimethylsiloxane Injection in Prevention of Recurrent Graft Pyelonephritis for Transplanted Kidney with Vesicoureteral Reflux.

    L. Nison,1 M. Hazzan,2 P. Puech,3 S. Bouye.1

    1Urology, University of Lille, Lille, France; 2Nephrology, University of Lille, Lille, France; 3Radiology, University of Lille, Lille, France.

    Reccurent acute graft pyelonephritis (AGPN) with vesicoureteral reflux (GVUR) can have a deleterious impact on graft outcome. The objective of this study was to evaluate…
  • 2016 American Transplant Congress

    Profiling of T Cell Subsets in a Primate Cardiac Transplant Model.

    N. O'Neill, T. Zhang, G. Braileanu, W. Sun, X. Cheng, C. Evans, R. Pierson, A. Azimzadeh.

    Surgery, University of Maryland, Baltimore, MD.

    Purpose: Costimulation blockade prolongs graft survival but does not induce tolerance in primates, and mechanisms of rejection are incompletely understood. Here we evaluate changes in…
  • 2016 American Transplant Congress

    Impact of Donor AKI on Outcome Following High KDPI Deceased Donor Kidney Transplantation.

    D. Haakinson,1 I. Qaqish,2 M. Smith,3 H. Khamash,2 K. Reddy,1 R. Heilman.2

    1Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ; 2Nephrology, Mayo Clinic Arizona, Phoenix, AZ; 3Pathology, Mayo Clinic Arizona, Phoenix, AZ.

    Background: Transplanting deceased donor kidneys with AKI does not appear to have negative impact on graft survival, however the impact of AKI on high KDPI…
  • 2016 American Transplant Congress

    Kidney Graft Homing of De Novo Donor Specific HLA Antibodies Is an Early Step within the Antibody-Mediated Graft Damage Process.

    A. Nocera,1 M. Cioni,2 A. Tagliamacco,1 A. Innocente,3 I. Fontana,4 A. Magnasco,2 A. Nocco,3 A. Sementa,2 G. Garibotto,1 G. Ghiggeri,2 M. Cardillo,3 P. Comoli,5 F. Ginevri.2

    1Transplant Immunology and Nephrology, University of Genova, Genova, Italy; 2Nephrology and Pathology, G. Gaslini Institute, Genova, Italy; 3Transplantation Immunology, Fondazione Cà Granda Ospedale Maggiore Policlinico, Milano, Italy; 4Kidney Transplant Surgery, IRCCS S.Martino-IST, Genova, Italy; 5Pediatric Hematology/Oncology, IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy.

    In this study, by a parallel analysis on sera and graft biopsies we have analyzed, in a pediatric cohort of unsensitized recipients of a first…
  • 2016 American Transplant Congress

    Kidney Transplant with Low Level DSA and Low Positive B-Flow Crossmatch: An Underappreciated Option for Highly Sensitized Transplant Candidates.

    C. Schinstock, W. Cheungpasitporn, F. Cosio, D. Mitema, M. Gandhi, M. Prieto, P. Dean, M. Stegall.

    Transplant Center, Mayo Clinic, Rochester, MN.

    Introduction: Avoiding DSA is difficult in sensitized patients. A kidney transplant (KTx) with low level DSA with or without a low level B flow cytometric…
  • 2016 American Transplant Congress

    The Burden and Outcomes of Fractures in Kidney Transplant Recipients.

    N. Atagu, T. Nguyen, N. Phan, O. Famure, Y. Li, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.

    Background: Kidney transplantation confers an increased risk for bone fractures. However, there is poor consensus on the incidence of fractures in kidney transplant recipients (KTRs),…
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