2016 American Transplant Congress
Fecal Microbiota Transplant Results in Durable Changes to Host Microbiota That Correlate with Allograft Outcome.
CVID and IGS, University of Maryland School of Medicine, Baltimore, MD.
Hypothesis: We previously presented highly significant differences in the bacterial community structures of human renal allograft recipients over time. Likewise, murine normal, colitic, and pregnant…2016 American Transplant Congress
Machine Perfusion (MP) at 21[deg]C Simulates Hibernation Metabolic Pathways in a Non-Hibernator Mammal.
University of Pittsburgh, Pittsburgh.
Background: Hibernation is a complex and multi stage process that leads to unique metabolic changes over an extended period of time. Regulatory genes and transcription…2016 American Transplant Congress
Donor-Recipient Absolute Weight Mismatch and the Risk of Graft Loss in Renal Transplantation.
Background: Relatively smaller kidney donor to recipient size is proposed to result in increased graft loss due to nephron underdosing and hyperfiltration injury but few…2016 American Transplant Congress
Influence of Pancreas Import and Cold Ischemia on Outcomes Following Pancreas Transplantation.
1Surgery, Wake Forest, Winston-Salem, NC; 2Internal Medicine, Wake Forest, Winston-Salem, NC.
Proposed changes in pancreas transplant (PT) allocation may improve organ sharing but increase cold ischemia time (CIT). Methods: We performed a single center, retrospective study…2016 American Transplant Congress
Evaluating Delayed Graft Function After Kidney Transplantation as a Potential Surrogate Outcome.
Department of Surgery, Johns Hopkins, Baltimore, MD.
Background: Recent work demonstrates significant inter-center heterogeneity in delayed graft function (DGF) rates after kidney transplantation, calling into question the value of a metric based…2016 American Transplant Congress
Heterologous Persistent and Latent Viral Infections Do Not Impact Graft Survival.
1Duke University, Durham; 2Emory University, Atlanta.
Purpose: Infection induces costimulation-resistant memory T cells with heterologous alloreactivity. Rapamycin has been shown to mitigate the effect of these cells in transplant rejection. Previous…2016 American Transplant Congress
Prolonged Pre-Transplant Dialysis Duration Reverses the “Nephroprotective Effect” in Simultaneous Liver-Kidney Transplant Recipients.
University of Florida, Gainesville.
Past literature has suggested that simultaneous liver-kidney(SLK) transplant recipients may experience a nephroprotective effect compared to kidney(Ki) alone transplant recipients. Since hepatorenal syndrome is a…2016 American Transplant Congress
Clinical Significance of C3d Binding Donor Specific Anti-HLA Antibodies (DSA) Detected by Single Antigen Beads (SAB) After Kidney Transplantation.
A new Luminex-based SAB method detects DSA compliment fixing via C3d-binding. This study compares the clinical outcomes in kidney recipients that developed de novo DSA…2016 American Transplant Congress
The Combined Effect of Acute Rejection and De Novo Donor-Specific Antibodies on Kidney Allograft Survival.
Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO.
While dnDSA is associated with graft loss in multiple studies, the clinical context in which dnDSA develops and contributes to graft loss is less well…2016 American Transplant Congress
Post-Transplantation Hypomagnesemia as a Predictor of Survival Among the Kidney Transplant Population.
Transplant Research Center, Brigham and women's hospital, Boston, MA.
We have previously shown a robust relationship between low magnesium in the first year post-transplant and better long-term kidney allograft function. Given this somewhat counterintuitive…
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