ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2016 American Transplant Congress

    Everolimus Abrogates C5a and TGFβ Mediated Perycite-to-Myofibroblast Transition (PMT) Inhibiting Vascular Rarefaction.

    G. Castellano, R. Franzin, A. Stasi, C. Divella, L. Gesualdo.

    Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.

    Microvascular pericytes have detrimental effects on tubulo-interstitial fibrosis via PMT. However, therapeutic strategies that might interfere with this process are currently lacking. We aimed to…
  • 2016 American Transplant Congress

    The Treatment of Borderline Lesion in Protocol Biopsies Did Not Improve the Outcome in Kidney Transplant Recipients.

    A. Flores-Mendoza, L. Marino-Vazquez, A. Guichard-Romero, N. Uribe-Uribe, R. Rivera-Marfil, A. Nuñez-Abreu, J. Alberu, L. Morales-Buenrostro.

    Nephrology, Transplantation and Pathology, National Institute of Medical Sciences and Nutrition SZ, Mexico, Distrito Federal, Mexico.

    Introduction. Up to 30% of patients with protocol biopsies and stable renal function have borderline lesions. His relationship with acute rejection remains uncertain, as does…
  • 2016 American Transplant Congress

    Evaluation of a Risk-Stratified Induction Immunosuppression Protocol Utilizing Low-Dose Antithymocyte Globulin in Renal Transplantation.

    A. Diamond, Z. Khawaja, M. Simpson, S.-C. Kung, M. Akoad, J. Pomposelli, E. Pomfret.

    Solid Organ Transplantation & Hepatobiliary Diseases, Lahey Hospital and Medical Center, Burlington, MA.

    Lower doses of rabbit-derived antithymocyte globulin (rATG) may result in less infection and cost, but may increase the incidence of acute rejection. We compared the…
  • 2016 American Transplant Congress

    Criteria for the Diagnosis of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx).

    J. Grande,1 R. Leduc,2 The DeKAF Study Group.

    1Dept. of Lab Medicine & Pathology, Mayo Clinic College of Medicine, Rochester, MN; 2Division of Biostatistics, U. Minnesota School of Public Health, Minneapolis, MN.

    The presence of MVI (Banff glomerulitis "g" score and Banff peritubular capillary "ptc" score) in KTxBx, often related to antibody mediated rejection (AMR), is associated…
  • 2016 American Transplant Congress

    Influence of AKIN Stage on the Outcome of Deceased Donor Kidney Transplantation (DDKTx).

    I. Qaqish, D. Haakinson, K. Reddy, M. Smith, H. Khamash, H. Raymond.

    Mayo Clinic, Phoenix, AZ.

    BackgroundTransplanting kidneys from donors with AKI is one of the methods to minimize the disparity between numbers of listed patient and donor pool. Our aim…
  • 2016 American Transplant Congress

    Donor-Candidate Mismatch in Age, Sex, HLA, and Body Size Inform a Calculator for Kidney Graft Survival.

    J. Kalbfleisch,1 V. Ashby,1 A. Leichtman,2 M. Rees,3 P. X.-L. Song,1 A. Sakhuja,1 M. Bray,1 R. Eikstadt,1 A. Goulding,1 W. Wang.1

    1Univ of Michigan, Ann Arbor; 2Arbor Research, Ann Arbor, MI; 3Univ of Toledo, Toledo, OH.

    Using Scientific Registry of Transplant Recipients data, we analyzed 232,705 kidney transplant recipients that received a transplant from 1998-2012. Graft failure rates were estimated using…
  • 2016 American Transplant Congress

    Should Obese Patients Undergo Renal Transplantation? A Retrospective Analysis to Assess Whether Body Mass Index Can Affect Transplant Outcome.

    A. Mehta,1 A. Marriott,1 A. Ghazanfar.2

    1St. George's, University of London, London, United Kingdom; 2Renal Transplant Unit, St. George's Hospital, London, United Kingdom.

    This study aims to analyze our renal transplant recipient population in terms of perioperative complications (90 day) and graft survival (3 years) in relation to…
  • 2016 American Transplant Congress

    Long Term Heterotopic Cardiac Xenograft Survival from Donor Pigs with Six Gene Modifications.

    M. Mohiuddin,1 A. Singh,1 J. Chan,1 P. Corcoran,1 M. Thomas III,2 B. Lewis,2 D. Ayares,3 K. Horvath.1

    1CSRP, NHLBI/NIH, Bethesda, MD; 2DVR / RS, NIH, Bethesda, MD; 3Revivicor, Inc, Blacksburgh, VA.

    Introduction: We have recently reported pig xenograft survival of more than 2.5 years in a heterotopic cardiac xenograft model. Some of the animals exhibited local…
  • 2016 American Transplant Congress

    The UKKDRI Score Predicts Outcomes of Deceased Donor Transplantation Using a Steroid Sparing Immunosuppressive Protocol.

    A. Wardle, M. Willicombe, D. Goodall, A. McLean, D. Taube.

    Imperial College REnal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    The UK kidney donor risk-index (UKKDRI) was developed to provide a simplistic clinical tool to help determine quality of an allograft and aid informed consent.…
  • 2016 American Transplant Congress

    Risk Stratification for Optimized Utilization of Deceased Donor Kidneys with Acute Kidney Injury by KDIGO Criteria.

    B. Yu,1 T. Koo,2 J. Lee,3 J. Yang,2 J. Ha,4 C. Ahn,1 Y. Kim,1 H. Lee.1

    1Internal Medicine, Seoul National University Hospital, Seoul, Korea; 2Transplantation Center, Seoul National University Hospital, Seoul, Korea; 3Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; 4General Surgery, Seoul National University Hospital, Seoul, Korea.

    BackgroundDeceased donor kidneys with acute kidney injury (AKI) raise fear of poor graft outcomes to the transplant clinicians and consequently are often discarded. However, the…
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