Articles tagged "Graft survival"

2017 American Transplant Congress
Mitochondrial Permeability Can Regulate Endothelial Cell Necroptosis and Promote Cardiac Allograft Rejection.
I. Gan,^1,2 J. Jiang,¹ D. Lian,¹ A. Jevnikar,^1,3 Z.-X. Zhang.^1,2
¹Matthew Mailing Centre for Translational Transplant Studies, Western University, London, ON, Canada; ²Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada; ³Department of Medicine, Western University, London, ON, Canada
Background: Transplant injury is invariably associated with programmed cell death (PCD) resulting in organ rejection. Many forms of PCD have been described including apoptosis, pyroptosis,…
2017 American Transplant Congress
Reduced Rituximab with Prophylactic Antibiotic Treatment Improves the Infectious Complications in Patients Undergoing ABO-Incompatible Living Donor Liver Transplantation.
S.-C. Hsu, A. Thorat, L.-B. Jeng, H.-R. Yang, P.-C. Li, C.-C. Yeh, T.-H. Chen, K.-S. Poon.
Organ Transplantation, China Medical University Hospital, Taichung, Taiwan
Introduction:ABO incompatible (ABOi) living donor liver transplantation (LDLT) is a feasible alternative for donor liver allograft in emergency situations. The reported outcomes of ABOi-LDLT after…
2017 American Transplant Congress
Kidney Donation After Brain Death Followed by Circulatory Death Confers Comparable Outcomes with Kidney Donation After Brain Death.
Q. Sun,¹ Q. Sun,¹ H. Zhou,² R. Cao,³ M. Lin,⁴ X. Hua,¹ L. Hong,¹ Z. Huang,¹ N. Na,¹ R. Cai,⁴ G. Wang,² F. Meng.³
¹Renal Transplantation, Lingnan Hospital, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Urology, The First Affiliated Hospital, Jilin University, Changchun, China; ³Renal Transplantation, The Second Affiliated Hospital, Guangzhou Traditional Chinese Medicine University, Guangzhou, China; ⁴Renal Transplantation, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
The shortage of donor organs is an obstacle to meet the growing need of grafts. Although using DBD donors is the best available strategy, brain…
2017 American Transplant Congress
Safety and Decreased Inflammation of Early Double Cytokine Blockade (IL-1β and TNF-α) Facilitates Engraftment in Islet Allotransplantation.
N. Onaca,¹ M. Takita,² M. Levy,³ B. Naziruddin.¹
¹Simmons Transplant Institute, Baylor University Medical Center, Dallas; ²Baylor Scott and White Research Institute, Dallas; ³Hume Lee Transplant Center, Virginia Commonwealth University, Richmond
Enhanced early islet engraftment offers the potential for improved graft function after islet allotransplantation (IT). Nine patients underwent IT under a fully completed prospective research…
2017 American Transplant Congress
The Clinical Significance of Red Cell Distribution Width (RDW) in Kidney Transplant Recipients.
S. Park,¹ J. Ha,¹ Y. Kim,¹ H. Lee,¹ Y. Kim,¹ C. Lim,¹ I. Jung,¹ D.-J. Han,² S.-K. Park,² Y. Kim,² J. Lee.¹
¹Seoul National University College of Medicine, Seoul, Korea; ²Asan Medican Center, Seoul, Korea
Background Increased red cell distribution width (RDW) has been known to be associated with worse prognosis in various populations. Although the levels of RDW are…
2017 American Transplant Congress
A Single Skin Commensal Strain Is Sufficient to Accelerate Skin Transplant Rejection.
Y. Lei,¹ L. Chen,¹ Y. Wang,¹ A. Chong,¹ Y. Belkaid,² M.-L. Alegre.¹
¹Departments of Medicine and Surgery, University of Chicago, Chicago, IL; ²Immunity at Barrier Sites Initiative, NIAID, NIH, Bethesda
The kinetics of graft rejection depend mostly on the extent of genetic disparities between organ donor and recipient, but appreciation that environmental factors may also…
2017 American Transplant Congress
Inferior Graft and Patient Survival After Living Donor Renal Transplantation of Negatively Selected Right Kidneys.
S. Yamanaga,^1,2,3 A. Posselt,¹ C. Freise,¹ C. Niemann,¹ A. Rosario,¹ D. Fernandez,¹ T. Kobayashi,³ A. Ahearn,⁴ M. Tavakol,¹ S.-M. Kang.¹
¹Department of Surgery, UCSF, San Francisco, CA; ²Department of General Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan; ³Department of Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan; ⁴Department of Transplant Surgery, UMass Memorial Medical Center, Worcester, MA
Purpose: In living donor renal transplantation, the left kidney is usually chosen for anatomical reasons. The right kidney is sometimes chosen if it is believed…
2017 American Transplant Congress
Transplant Center Variability in Disparities for African-American Kidney Transplant Recipients.
D. Taber, M. Gebregziabher, L. Egede, P. Baliga.
MUSC, Charleston, SC
Disparities research has traditionally focused on patient-level variables to ascertain predominant risk factors driving differences in outcomes for African-American (AA) kidney transplant (KTX) recipients. The…
2017 American Transplant Congress
iNKT Cell Activation Plus Veto Cell Transfer Yields Complete Chimerism in a Murine Sub-Lethal Bone Marrow Transplant Model.
R. Ishii,¹ T. Hirai,¹ Y. Ishii,² M. Okumi,¹ K. Tanabe.¹
¹Department of Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Cluster for Industry Partnerships (CIP), RIKEN, Yokohama, Japan
Transplant tolerance induction makes it possible to preserve functional grafts for a lifetime without immunosuppressants. We have previously established a novel method for mixed chimera…
2017 American Transplant Congress
Dexamethasone Prolongs Cardiac Allograft Survival in a Murine Model Through Myeloid-Derived Suppressor Cells.
T. Nakao,¹ T. Nakamura,¹ K. Masuda,¹ T. Matsuyama,¹ H. Ushigome,¹ E. Ashihara,² N. Yoshimura.¹
¹Organ Transplantation and Regenerative Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; ²Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan
Recently, myeloid-derived suppressor cells (MDSCs) have attracted considerable attention because of their cancer-promoting and immunosuppressive effects. The glucocorticoid (GC) dexamethasone (Dex) is an important immunosuppressive…