Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Purpose of the study was to explore the effect of admit AKI donor creatinine on graft outcomes.
Method: Single center retrospective analysis of kidney transplants performed using organs from deceased AKI donors (terminal creatinine ≥ 2 mg/dl). Combined organ transplants were excluded. AKI kidneys with cortical necrosis or moderate/severe chronic changes were discarded. The cohort was divided based on admit donor creatinine (< or ≥ 1.5 mg/dl). Outcomes were graft survival, DGF, 1-, 4-month and 1-year creatinine/eGFR and Banff staging.
Results: 387 patients were included. 171 recipients had a donor admit creatinine ≥ 1.5 mg/dl (group 1), while the rest (group-2) a creatinine < 1.5 mg/dl. Group-1 donors were younger, female, with lower KDPI, non-hypertensive, oliguric and with higher terminal and peak creatinine levels.
|Peak creat. (mg/dl)||6.38±2.91||4.15±1.99||<.0001|
Group-1 recipients were younger, with higher 1-week creatinine which became lower 4 months post-transplant. 1-year eGFR (CKD EPI formula) was better in group-1.
|4-month creat. (mg/dl)||1.35±0.47||1.58±0.82||0.0012|
|4-month eGFR (ml/min/1.73m2)||60.3±20||52.0±20.8||0.0002|
|1-yr eGFR||62.1 ±21.6||55.5±21.0||0.0137|
CITATION INFORMATION: Giorgakis E, Heilman R, Khamash H, Kaplan B, Moss A, Smith M, Reddy K. Effect of AKI Donor Admit Creatinine on Renal Transplant Outcomes. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:Giorgakis E, Heilman R, Khamash H, Kaplan B, Moss A, Smith M, Reddy K. Effect of AKI Donor Admit Creatinine on Renal Transplant Outcomes. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/effect-of-aki-donor-admit-creatinine-on-renal-transplant-outcomes/. Accessed January 20, 2020.
« Back to 2017 American Transplant Congress