Articles tagged "Graft survival"

2017 American Transplant Congress
Post Transplant Outcomes in Hepatitis C Positive Patients.
M. Lubetzky, N. Hayde, L. Kamal, M. Ajaimy, P. Bedi, G. Deboccardo, J. Rocca, S. Greenstein, J. Graham, A. Chokechanachaisakul, A. Courson, M. Kinkhabwala, E. Akalin.
Montefiore Medical Center, Bronx
Hepatitis C (HCV) is associated with increased morbidity and mortality after kidney transplant (KTx). We aimed to assess outcomes of HCV positive patients at our…
2017 American Transplant Congress
Vascularized Bone Marrow Mechanisms of Immunomodulation.
A. Khalifeh, E. Buckingham, M. Uluer, W. Hassanein, W. Twaddell, C. Drachenberg, A. Nam, S. Bartlett, R. Barth.
University of Maryland School of Medicine, Baltimore, MD
Introduction:Hand and face transplants containing co-transplanted bone may have improved outcomes. We have previously utilized a NHP model to demonstrate that VCA containing VBM have…
2017 American Transplant Congress
De-Novo Portal Vein Thrombosis After Adult-to-Adult Living Donor Liver Transplantation (LDLT) Does Not Impact on Long-Term Outcome.
I. Linares,¹ N. Goldaracena,¹ R. Rosales,¹ L. De La Maza,¹ J. Echeverri,¹ M. Kaths,¹ D. Kollman,¹ N. Selzner,² S. McCluskey,³ G. Sapisochin,¹ L. Lilly,² P. Greig,¹ M. Bhat,² A. Ghanekar,¹ M. Cattral,¹ I. McGilvray,¹ D. Grant,¹ M. Selzner.¹
¹Department of Surgery, Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; ²Department of Medicine, Multi-Organ Transplant Program, Toronto General Hospital University Health Network, Toronto, ON, Canada; ³Department of Anesthesiology, Toronto General Hospital, University Health Network, Toronto, ON, Canada
Portal vein thrombosis(PVT) after deceased donation has been widely described as a liver transplant complication that can lead to graft failure, high morbidity and mortality.…
2017 American Transplant Congress
Differences in Racial and Sex Disparities in Liver Transplantation Outcomes Between Older and Younger Adult Recipients.
Q. Huang, C. Haugen, X. Luo, A. Massie, M. McAdams-DeMarco, D. Segev.
Johns Hopkins University, Baltimore
Background: More older adults underwent liver transplantation (LT) in the past decade. While racial and sex disparities in LT outcomes have been reported in general,…
2017 American Transplant Congress
Deciphering the Mechanism of Remote Ischemic Preconditioning and Its Potential Benefits in Ischemia/Reperfusion Injury by Metabolomics.
S. Cho, S.-I. Min, S.-Y. Kim, M.-J. Cho, W. Cho, S. Ahn, S.-K. Min, J. Ha.
Surgery, Seoul National University Hospital, Seoul, Korea
IntroductionRemote ischemic preconditioning (RIPC) is a strategy inducing resistance against ischemia and reperfusion(IR) injury. But the mechanism and the time window of protection representing RIPC…
2017 American Transplant Congress
Incidence and Outcomes of Immediate Post-Operative Dialysis in Liver Transplantation.
S. Nagai, M. Safwan, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud.
Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
Aim: Although kidney dysfunction secondary to hepatorenal syndrome is expected to recover with liver transplant alone (LTA), patients with pre-transplant marginal kidney function may be…
2017 American Transplant Congress
Long-Term Outcome of Antibody-Mediated Rejection Due to Pre-Existing vs. De Novo DSA in Kidney Allograft Recipients.
O. Aubert,¹ C. Lefaucheur,¹ S. Higgins,¹ L. Hidalgo,² J. Duong Van Huyen,¹ D. Viglietti,¹ X. Jouven,¹ D. Glotz,¹ P. Halloran,² A. Loupy.¹
¹Paris Translational Research Center for Organ Transplantation, Paris, France; ²ATAGC, Edmonton, Canada
BackgroundAntibody-mediated rejection (ABMR) can occur in patients with pre-existing anti-HLA donor-specific antibodies (DSA) or in patients who develop de novo DSA. However, how these processes…
2017 American Transplant Congress
Kidney Injury Molecule-1 Mitigates Tissue Damage from Transplant Renal Ischemia Reperfusion Injury.
J. Lee,^1,2 X. Zhang,² A. Haig,³ D. Lian,² P. Anderson,² R. Navaratnam,² L. Gunaratnam.^1,2
¹Department of Microbiology and Immunology, Western University, London, ON, Canada; ²Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; ³Department of Pathology, Western University, London, ON, Canada
Ischemia reperfusion injury (IRI) at the time of organ harvesting is unavoidable, may cause delayed renal graft function, and is associated with premature graft loss.…
2017 American Transplant Congress
Benefits of Induction in Recipients of Acute Renal Failure Donor Kidneys.
M. Barrett, A. Smith, K. Woodside, R. Sung.
University of Michigan, Ann Arbor
Kidneys from donors with acute renal failure (ARF) are often discarded due to concerns for DGF and graft failure. Induction immunosuppression can be used to…
2017 American Transplant Congress
Belatacept Conversion in Kidney Recipients with Low GFR Does Not Improve Renal Function.
D. Abdelwahab,¹ S. Byron,² B. Kaplan,¹ R. Heilman.¹
¹Transplant, Mayo Clinic, Scottsdale, AZ; ²Biostatistics and Informatics, Mayo Clinic, Rochester, MN
Background:Belatacept interferes with signal 2 of T cell activation via blockade CD80/86 which doesn't adversely impact renal function. We tested a hypothesis that Belatacept conversion…