ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2022 American Transplant Congress

    PACAP-Mediated Autophagy Prevents Liver Ischemia Reperfusion Injury in OLT

    Z. Xue, B. Yang, R. Busuttil, J. Kupiec-Weglinski, H. Ji

    UCLA Medical Center, Los Angeles, CA

    *Purpose: Pituitary adenylate cyclase-activating polypeptide (PACAP) is from vasoactive intestinal peptide-glucagon-secretin family. Our group was the first to demonstrate that neuropeptide PACAP, which innervates the…
  • 2022 American Transplant Congress

    High KDPI Kidneys: Lifelong Freedom from Dialysis for Elderly Patients

    M. M. Romine1, W. Irish2, H. Jones3, A. Aaron2, D. Leeser4

    1Department of Surgery, Eastern Carolina University, Greenville, NC, 2Eastern Carolina University, Greenville, NC, 3Eastern Nephrology Associates, Greenville, NC, 4East Carolina University, Greenville, NC

    *Purpose: According to national data, there is an increase in kidney transplants in patients over 65, corresponding to an overall general increase. Elderly patients continue…
  • 2022 American Transplant Congress

    PSGL-1-mTOR-TIM3 Signaling in a Murine Model of Hindlimb Transplantation

    K. Kadono1, F. Messner2, J. He2, Y. Guo2, B. Oh2, G. Brandacher2, J. Kupiec-Weglinski1

    1UCLA Medical Center, Los Angeles, CA, 2Johns Hopkins UJohns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: Peri-transplant tissue damage driven by innate-adaptive immune cascades resulting from ischemia-reperfusion injury (IRI) is a major concern in vascularized composite allotransplantation (VCA). Here, we…
  • 2022 American Transplant Congress

    Does Donor-to-Recipient Weight Mismatch Influence Short Term Outcomes of Deceased Donor Kidney Transplantation?

    L. Sabbagh, M. Killackey, H. Jeon, K. Atiemo, A. Paramesh, A. Vijay

    Tulane University School of Medicine, New Orleans, LA

    *Purpose: The functional nephron mass of an allograft is often taken into consideration when contemplating transplanting a small kidney into a large recipient. We aim…
  • 2022 American Transplant Congress

    Tocilizumab in Chronic Active Antibody-Mediated Rejection in Kidney Transplant Recipients: A Case Series

    B. Boonpheng1, R. Bakthavatsalam2, C. D. Blosser1, I. C. De Castro1, I. Gimferrer3, Y. Ng1, N. Leca1

    1Nephrology, University of Washington, Seattle, WA, 2Surgery, University of Washington, Seattle, WA, 3Bloodworks Northwest, Seattle, WA

    *Purpose: The optimal treatment for chronic active antibody-mediated rejection (ca-AMR) remains unclear. Tocilizumab (TCZ), a monoclonal antibody against IL-6, has been proposed in ca-AMR treatment…
  • 2022 American Transplant Congress

    Influence of Converting Kidney Transplant Recipients with High Tacrolimus Variability to the Once Daily LCP Tac Formulation

    D. Taber, F. Bartlett, N. Patel, T. Sprague, S. Patel, J. Newman, E. Andrade, N. Rao, A. Posadas, V. Rao, M. Casey, D. Dubay, V. Rohan

    Med Univ of South Carolina, Charleston, SC

    *Purpose: Tacrolimus (Tac) is the cornerstone of immunosuppression used in kidney transplant recipients (KTRs). Tac high variability, low time in therapeutic range and non-adherence are…
  • 2022 American Transplant Congress

    Vitrification of Pancreatic Islets and Transplantation

    J. S. Rao1, L. Zhan1, D. Tobolt1, M. Q. Slama2, N. Sethia1, Z. Han1, C. S. Dutcher1, Q. Peterson2, J. C. Bischof1, E. B. Finger1

    1University of Minnesota, Minneapolis, MN, 2Mayo Clinic, Rochester, MN

    *Purpose: A limitation to potential cure for diabetes through islet transplantation is insufficient islet equivalence (IEQ) from a single donor to achieve insulin independence in…
  • 2022 American Transplant Congress

    Final Flow and Resistance During Cold Pulsatile Perfusion Preservation Do Have Value in Prediction of Deceased Donor Graft Survival After Adjusting for KDPI

    D. S. Keith, E. Lessmann

    Kidney Transplant, Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine whether cold pulsatile perfusion preservation (CPPP) parameters of flow and resistance provide additional data regarding deceased donor kidney graft survival after adjusting…
  • 2022 American Transplant Congress

    Outcome of Pre-Emptive Kidney Transplantation in Children Under 6 Years of Age; A Single Center Experience in Japan

    Y. Aoki1, Y. Hamasaki1, J. Hashimoto1, A. Zaitsu2, M. Kubota1, M. Muramatsu1, T. Kawamura1, S. Shishido2, K. Sakai1

    1Nephrology, Toho University Faculty of Medicine, Tokyo, Japan, 2Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan

    *Purpose: Kidney transplantation (KT) is the preferred treatment for pediatric end stage renal disease, and pre-emptive kidney transplantation (PEKT) may reduce morbidity and mortality. KT…
  • 2022 American Transplant Congress

    Clinical Significance of Delayed Graft Function and Slow Graft Function in Living Donor Kidney Transplantation

    J. Song1, S. Jeong1, S. Min1, J. Ha1, J. Lee2, J. Jeong3, Y. Kim1, Y. Kim1, H. Lee1

    1Seoul National University Hospital, Seoul, Korea, Republic of, 2Boramae Medical Center, Seoul, Korea, Republic of, 3Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of

    *Purpose: The delayed graft function (DGF) after kidney transplantation (KT) affects long-term graft and patient survival. We explored the time-trend of DGF and associated risk…
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