Articles tagged "Graft survival"

2017 American Transplant Congress
Poor Outcome of Polyomavirus -Associated Nephropathy with Glomerular Parietal Epithelial Cells Infected by Polyomavirus.
G. Huang,¹ W. Chen,² J. Qiu,¹ X. Chen,¹ L. Chen,¹ C. Wang.¹
¹Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
Background: Bowman's capsular epithelium infected by polyomavirus(Py) in polyomavirus -associated nephropathy (PyVAN) is infrequent and considered as the advanced stage of the disease. The aim…
2017 American Transplant Congress
C1q+ and IgG3+ De Novo Donor Specific Antibody Are Associated with Allograft Failure in a Multicenter Cohort.
C. Schinstock,¹ M. Everly,² M. Samaniego,³ M. Gandhi,¹ R. Parikh,⁴ V. Sharma,⁴ M. Stegall,¹ D. Dadhania.⁴
¹Mayo Clinic, Rochester, MN; ²Terasaki Research Institute, Los Angelos, CA; ³University of Michigan, Ann Arbor, Mi; ⁴Cornell University, New York, NY
Introduction: De novo donor specific antibody (dnDSA) is a risk factor for antibody mediated rejection and allograft loss, but dnDSA does not always lead to…
2017 American Transplant Congress
Liver Transplantation for Adolescents with Biliary Atresia in the PELD/MELD Era: An Analysis of the UNOS Database.
J. Chu,^1,2 R. Annunziato,³ D. Reinoso,³ A. Ramaswami,² R. Arnon.^1,2
¹Recanati/Miller Transplantation Institute, Mount Sinai Medical Center, New York, NY; ²Pediatrics, Mount Sinai Medical Center, New York, NY; ³Department of Psychology, Fordham University, Bronx, NY
While poor bile drainage after a Kasai hepatoportoenterostomy (KPE) is the primary driver for liver transplantation (LT) for Biliary Atresia (BA) in infancy, the data…
2017 American Transplant Congress
Kidney Transplantation in Octogenarians: The Mayo Clinic Experience.
N. Khoury, T. Schwab, M. Prieto, H. Amer.
Transplant Center, Mayo Clinic, Rochester, MN
BackgroundKidney transplantation (KTx) is the preferred renal replacement therapy in selected individuals.There is limited data on transplantation of octogenarians. The purpose of this study was…
2017 American Transplant Congress
Steroid Withdrawal Using Everolimus in Maintenance Kidney Transplant Recipients with Post-Transplant Diabetes Mellitus.
K. Nanmoku, A. Kurosawa, T. Kubo, T. Shinzato, T. Shimizu, T. Kimura, T. Yagisawa.
Surgical Branch, Institute of Kidney Diseases, Jichi Medical University Hospital, Shimotsuke, Tochigi, Japan
Background: Although steroid withdrawal from conventional immunosuppressive therapy has been attempted to ameliorate various complications, especially diabetes mellitus (DM), in kidney transplant recipients, a steroid-sparing…
2017 American Transplant Congress
Long-Term Clinical Outcomes of Kidney Transplant Recipients with Body-Size Mismatch Between Recipient and Donor.
Y. Takada,¹ D. Iwami,¹ K. Hotta,¹ K. Kanagawa,² H. Higuchi,¹ T. Hirose,¹ H. Sasaki,¹ N. Shinohara.¹
¹Urology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan; ²Urology, Asahikawa City Hospital, Asahikawa, Hokkaido, Japan
[Purpose]In living-donor kidney transplantation between large recipient and small donor, there are concerns of lower graft function and poor graft survival. Thus, we aimed to…
2017 American Transplant Congress
Potential Mechanism Involving Regulatory T Cells in Induction of Tolerance in Mouse Vascularized Composite Allotransplantation Under Combined Costimulation Blockade.
M. Anggelia,^1,2 Y.-Y. Huang,³ W.-Y. Chuang,⁴ H.-Y. Cheng,¹ G. Brandacher,⁵ F.-C. Wei,^1,2 C.-H. Lin.^1,2
¹PRS, Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ²Chang Gung Medical College and Chang Gung University, Taoyuan, Taiwan; ³Nephrology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ⁴Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ⁵Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD
Background: Role of Regulatory T cells in vascularized composite allotransplantation (VCA) remains to be elucidated. In this study, we investigate potential mechanism involved in Tregs…
2017 American Transplant Congress
Ischemia-Reperfusion Injury-Induced Innate Immune Signaling in Human Orthotopic Liver Transplantation.
R. Sosa,¹ A. Zarrinpar,² M. Rossetti,¹ C. Lassman,¹ B. Naini,¹ N. Datta,² R. Busuttil,² D. Gjertson,¹ J. Kupiec-Weglinski,^1,2 E. Reed.¹
¹Pathology and Laboratory Medicine, University of California, Los Angeles, CA; ²Surgery, University of California, Los Angeles, CA
Background: Ischemia-reperfusion injury (IRI) is a major risk factor in the development of acute and chronic graft rejection in orthotopic liver transplantation (OLT); however, no…
2017 American Transplant Congress
Absence of Independent and Additional Predictive Ability of Preimplantation Kidney Allograft Biopsies for Long-Term Outcome: Population Based Study.
O. Aubert, D. Viglietti, C. Loheac, M. Rabant, C. Gosset, J. Duong Van Huyen, D. Glotz, C. Legendre, C. Lefaucheur, A. Loupy.
Paris Translational Research Center for Organ Transplantation, Paris, France
BackgroundA significant number of kidneys are discarded worldwide due to the suboptimal use of large kidney resources. The mean cause is the result of the…
2017 American Transplant Congress
A Comparison of Desensitization Protocols: Rituximab with/without Plasmapheresis in ABO-Incompatible Living Donor Liver Transplantation.
E. Lee, S. Kim, S. Lee, S.-J. Park.
Center for Liver Cancer, National Cancer Center, Goyang, Korea
Background: Plasmapheresis is a desensitization method used prior to ABO-incompatible (ABO-I) living donor liver transplantation (LDLT). However, studies on its usefulness in the rituximab era…