2017 American Transplant Congress
Dual Treatment of Suboptimal Doses of CsA and MSC Infusion Fully Prevents Acute Rejection in an Allogenic Model of Renal Transplantation.
The immunomodulatory characteristics of mesenchymal stem cells (MSCs) may lead to multifaceted strategies in rejection of organ transplantation. This study was designed to investigate the…2017 American Transplant Congress
New Approach for Targeted Immunotherapy in Vascularized Composite Allotransplantation.
Vascularized composite allotransplantation (VCA) have highly immunogenic skin component mandates high doses of systemic immunosuppressive drugs. Oral dosing leads to fluctuating, unpredictable blood levels that…2017 American Transplant Congress
mTORC1 and 2 Regulate Dendritic Cell (DC) Metabolism and Allostimulatory Function of Donor DCs in Skin Transplantation.
Background/Hypothesis: The mechanistic target of rapamycin (mTOR) is a kinase that functions in two complexes: rapamycin (RAPA)-sensitive mTORC1 and RAPA-insensitive mTORC2. These complexes play critical…2017 American Transplant Congress
Prolonged Cold Ischemia Time as a Risk for Low Regeneration at the Early Phase After Living Donor Liver Transplantation.
Background. The objective of this study was to determine the risk factors for low liver regeneration at the early phase after living donor liver transplantation…2017 American Transplant Congress
Does Gender Affect Renal Transplant Outcomes?
Many studies have evaluated the role of gender on renal transplantation.Females (F) are less likely than males (M) to be on the waitlist (WL); less…2017 American Transplant Congress
Heat Shock Protein 90 Inhibitor, 17DMAG Suppresses Acute Allograft Rejection and Prolongs Allograft Survival in Solid Organ Transplantation.
Urology, Sapporo Medical University School of Medicine, Sapporo, Japan
Purpose: Heat shock protein 90 (HSP90) is a ubiquitously expressed molecular chaperone that is associated with the correct activation of client proteins. Important roles of…2017 American Transplant Congress
Small Pediatric Donor Kidney Transplantation in Pediatric Recipients.
Kidneys from small pediatric donors (age <5 years, weight <21 kg) may be a means to increase the donor pool for pediatric recipients. Transplantation of…2017 American Transplant Congress
Role of Donor-Derived Tissue Resident Memory T cells in Modulating Alloimmunity.
Emory Transplant Center, Emory University, Atlanta, GA
Recipient-derived, graft-specific memory T cells play a critical role in mediating allograft rejection, particularly in the setting of immunosuppression with costimulation blockade. Recently, it is…2017 American Transplant Congress
Assessment of Islet Damage During Isolation Utilizing miRNAs and Its Significance with Post-Transplant Outcome in TPIAT.
Background: Pancreatic islets with high quality are essential for better endocrine function and post-transplant outcome in total pancreatectomy with islet autotransplantation (TPIAT). The islets are…2017 American Transplant Congress
Outcomes of Organs Transplants When the Donor Is a Prior Recipient.
Introduction: Organ scarcity continues to limit the field of transplantation, which leads to death for patients on waiting lists. Organs from “Organ Donors After Transplant”…
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