2018 American Transplant Congress
10-Year Outcomes of Renal Transplantation from Circulatory Death Donors with Increased Terminal Creatinine
Surgery III, Tokyo Women's Medical University, Tokyo, Japan.
Background: To alleviate chronic renal graft shortages in Japan, donation after circulatory death (DCD) is an increasingly used organ resource. Organs from DCD donors with…2018 American Transplant Congress
TLR-Activated Bregs Promote Islet Allograft Tolerance in an IL-10-Independent and TGF-β-Dependent Manner
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Background: We previously demonstrated the potent capacity of regulatory B cells (Bregs) to mitigate allograft immunity. Recently, we produced TLR-activated B cells in vitro that…2018 American Transplant Congress
Complement Activating HLA Class 2 Antibodies Are Associated with Poor Renal Allograft Survival; Multicentre Study
IntroductionRole of Class I and II pre-formed complement activating antibodies on renal outcomes is not well defined. In this multicentre study, we looked at the…2017 American Transplant Congress
Anti-Angiotensin Type 1 Receptor Antibodies Associate with Rejection in Simultaneous Pancreas and Kidney Transplant and Pancreas Transplant Alone Recipients.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Background: Anti-angiotensin type 1 receptor antibodies (AT1R Ab) have been found to have a strong association with antibody mediated rejection (Reinsmoen et al, Transpl 2010;…2017 American Transplant Congress
Impact of Type of Recipient Diabetes on 1 and 3-Year Kidney Allograft and Patient Outcomes.
University of Michigan, Ann Arbor
The pathophysiology of type 1 (T1DM) and type 2 (T2DM) diabetes is different and has been conjectured to impact transplantation outcomes differently over time especially…2017 American Transplant Congress
Results of Biliary Reconstruction with PTFE Graft in Liver Transplantation.
Introduction: Biliary complications are often referred to as the 'Achilles heel' of liver transplantation (LT) with their high incidence rate, the need for repeated and…2017 American Transplant Congress
Inflammasome, Unfolded Protein Response, and T Cell Immunity in DAIH.
Background: Regulatory T cells (Tregs) of patients with de novo autoimmune hepatitis (DAIH) secrete IL-17A & IFN-g; display TH1 & TH17 pehnotypes & are functionally…2017 American Transplant Congress
Short- and Long-Term Graft Survival After Kidney Transplantation in Western Europe.
Background: Improvement of kidney survival after transplantation has mainly been studied in the American population. There, it was found that improvement mostly occurred on the…2017 American Transplant Congress
Deleting LAG-3 Accelerates Cardiac Allograft Rejection and Augments T Cell Memory in Mice.
Purpose: Lymphocyte Activation Gene-3 (LAG-3) expresses a transmembrane receptor on activated immune cells such as T cells, NK cells, and plasmacytoid dendritic cells. It is…2017 American Transplant Congress
Renal Transplant Outcomes in Primary FSGS Compared with Other Recipients: A National Review of the Irish Transplant Registry.
Primary focal segmental glomerular sclerosis (p-FSGS) raises specific peri-transplant concerns, one of which is disease recurrence (r-FSGS). We aimed to compare transplant outcomes in patients…
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