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American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2018 American Transplant Congress

    Improvement in Intermediate Graft Survival among Deceased Donor Recipients in the Last Decade Due to Improvements in Outcomes of Higher KDPI Kidney Recipients

    D. Keith.

    Medicine, Sacred Heart Hospital, Pensacola, FL, Turkey.

    Previous research by our group showed that intermediate graft survival of adult deceased donor kidney transplants between six months and three years post-transplant improved in…
  • 2018 American Transplant Congress

    Clinical Significance of Isolated v-Lesions in Kidney Transplantation

    A. Georgalis,1 C. Wehmeier,1 P. Hirt-Minkowski,1 G. Hönger,1 H. Hopfer,2 J. Steiger,1 S. Schaub,1 P. Amico.1

    1Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland; 2Institute for Pathology, University Hospital Basel, Basel, Switzerland.

    Background: Arteritis without significant tubulo-interstitial inflammation (v1-3, but i≤1 and t≤1) is referred by the 10th Banff conference as 'isolated v-lesions'. The clinical significance of…
  • 2018 American Transplant Congress

    Type I NKT Cells Augment Humoral and Cellular Alloimmunity in Response to Hepatocyte Transplantation

    S. Elzein, J. Zimmerer, B. Ringwald, C. Avila, G. Bumgardner.

    Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

    Hepatocyte transplantation (HcTx) is a potential therapeutic modality for patients with liver disease. Despite examples of antigen acceptance in the liver, allogeneic HcTx into patients…
  • 2018 American Transplant Congress

    Class II Anti-HLA IgG2 and IgG3 DSAs Predict Poorer Outcomes in Chronic Antibody Mediated Rejection of Renal Allografts

    A. Gueret-Wardle,1 G. Lucisano,1 S. Hassan,1 P. Brookes,2 E. Santos-Nunez,2 D. Goodall,1 C. Clarke,1 J. Galliford,1 M. Willicombe,1 D. Taube.1

    1Renal and Transplant Centre, Imperial College London NHS Trust, London, United Kingdom; 2Histocompatibility and Immunogenetics, Imperial College London, London, United Kingdom.

    Introduction: whilst the development of IgG3 and C1q binding de novo [dn] HLA DSAs are associated with a poor outcome in acute antibody mediated rejection,…
  • 2018 American Transplant Congress

    MERTK Mediates Transplant Tolerance via IFN-a Regulation of MDSCs and Tregs

    L. Zhang, M. DeBerge, E. Thorp, X. Luo.

    Northwestern University Feinberg School of Medicine, Chicago.

    Introduction: MERTK is one of the TAM receptor tyrosine kinases (RTKs) that mediate homeostatic phagocytosis of apoptotic cells, and transmit regulatory signals that modulate immune…
  • 2018 American Transplant Congress

    Liver Transplant Survival Index for Recipients with High MELD Score: A Model for Post-Transplant Survival in Severely Ill Patients

    J. Steggerda,1 M. Bloom,1 C. Bresee,2 D. Malinoski,3 A. Klein,1 K. Kim.1

    1Surgery, Cedars-Sinai Medical Center, Los Angeles, CA; 2Biostatistics, Cedars-Sinai Medical Center, Los Angeles, CA; 3Surgery, Oregon Health Science University, Portland, OR.

    Background: SHARE-35 prioritizes patients with MELD scores ≥35 for regional sharing of liver allografts. Because this policy incentivizes transplantation of sicker patients, this study examines…
  • 2018 American Transplant Congress

    Using the SRTR Expected Survival Worksheet to Estimate Expected Number of Events

    J. Gregg,1 K. Womer,1 K. Andreoni.2

    1Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL; 2Department of Surgery, University of Florida, Gainesville, FL.

    The purpose of this effort is to provide transplant administrative and clinical directors with reliable predictions of Scientific Registry of Transplant Recipients (SRTR) risk-adjusted 1-year…
  • 2018 American Transplant Congress

    When Does Donor Age Matter? A Review of over 70,000 Liver Transplants

    D. Yoeli, E. Pan, M. Kueht, N. Galvan, R. Cotton, C. O'Mahony, J. Goss, A. Rana.

    Surgery, Baylor College of Medicine, Houston, TX.

    Background: Past studies on donor age in liver transplantation have largely relied on binary groups (i.e., young vs. old) with arbitrarily defined cut-offs. The aim…
  • 2018 American Transplant Congress

    State of the Union: Outcomes of a Single Center's A2-to-B Transplants Two Years after the Implementation of KAS

    S. Radomski, S. Rosen-Bronson, D. Li, M. Awwad, G. Vranic, B. Javid, P. Abrams, S. Yi, M. Cooper, A. Gilbert.

    Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.

    Introduction. Since the implementation of the new KAS there are few reports on both single center outcomes in the modern era of transplantation and the…
  • 2018 American Transplant Congress

    Biochemistry Profiles Following Pig-to-Nonhuman Primate Liver Xenotransplantation

    N. Louras, M. Patel, J. Shah, D. Sachs, P. Vagefi.

    Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.

    Objectives:Clinical progress in liver transplantation has increased the demand for organs, however, supply remains stagnant. Porcine liver xenotransplantation (LXT) would help address this imbalance. Here…
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