Articles tagged "Graft survival"

2018 American Transplant Congress
Outcomes after Kidney Transplantation in Patients with AL Amyloid Following Autologous Stem Cell Transplantation
V. Gutgarts,^1,2 I. Jaffer Sathick,² C. Rosenbaum,³ T. Muthukumar,¹ H. Hassoun,⁴ C. Flombaum,² H. Landau.⁴
¹Nephrology, Weill Cornell, NY; ²Renal Medicine, Memorial Sloan Kettering, NY; ³Hematology, Weill Cornell, NY; ⁴Hematology, Memorial Sloan Kettering, NY.
BackgroundAL amyloidosis results in kidney failure in about 15-30% of patients and is considered a relative contraindication for kidney transplantation. There is limited data on…
2018 American Transplant Congress
Shikonin Inhibits Th17 Development through Repressing STAT3 Activation
H. Fang,¹ R. Zhang,¹ F. Liang,¹ Q. Chen,² J. Ochando,³ Y. Ding,¹ J. Xu.¹
¹Department of Immunology, Capital Medical University, Beijing, China; ²Department of Thoracic Surgery, Chaoyang Hospital, Beijing, China; ³Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Background: Th17-mediated inflammatory responses are detrimental for allograft acceptance and long-term survival after transplantation. Shikonin is a naphthoquinone pigment isolated from a traditional medicinal herb…
2018 American Transplant Congress
High Kidney Donor Profile Index (KDPI) Donor Kidneys: Use Them, Don't Lose Them!
D. Harriman, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, M. Gautreaux, W. Doares, S. Kaczmorski, R. Stratta.
Surgery, Medicine, Pathology, Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Introduction: With the development of the Kidney Donor Profile Index (KDPI) and a new Kidney Allocation System (KAS) implemented on 12/4/14, the expanded criteria donor…
2018 American Transplant Congress
Delayed Graft Function in Simultaneous Liver Kidney Transplantation
S. Weeks,¹ X. Luo,¹ S. Ottmann,¹ A. Gurakar,² F. Naqvi,² B. Philosophe,¹ A. Cameron,¹ N. Desai,¹ D. Segev,¹ J. Garonzik Wang.¹
¹Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD; ²Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: Increased rates of delayed graft function (DGF) after simultaneous liver kidney (SLK) transplantation have been described, as well as inferior graft survival in patients…
2018 American Transplant Congress
Individualized Immunosuppression through Risk-Stratification in Renal Transplantation Preserves Excellent Outcomes at Three Years
J. Dann, A. Agarwal, M. Bradley, J. Geyston, W. Ally.
University of Virginia Health System, Charlottesville, VA.
Risk-stratification of renal transplant recipients based on immunologic risk factors allows for tailored immunosuppression (IS), but long term follow up is limited. This study evaluates…
2018 American Transplant Congress
Identification of Anti-Inflammatory and Pro-Inflammatory Gut Microbiota That Determine Graft Survival
Y. Xiong, C. Brinkman, L. Hittle, W. Fricke, E. Mongodin, J. Bromberg.
UMB, MD.
Introduction: The gut microbiota induce and train the host immune system. Whether microbiota from contrasting environments of colitic or pregnant mice are pro- or anti-inflammatory…
2018 American Transplant Congress
The Impact of Aorto-Iliac Calcifications on Patient and Graft Survival in Renal Transplant Recipients Using the TASC II Classification
A. Rijkse,¹ M. van der Zijden,² J. Roodnat,² S. Ten Raa,³ D. Bijdevaate,⁴ K. Muller,¹ J. IJzermans,¹ H. Kimenai,¹ R. Minnee.¹
¹Department of Transplantation Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; ²Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; ³Department of Vascular Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; ⁴Department of Radiology, Erasmus University Medical Center, Rotterdam, Netherlands.
Introduction: Kidney transplantation (KTx) is the therapy of choice in patients with end-stage renal disease. Aorto-iliac calcifications (AIC) are a relative contra-indication for KTx, even…
2018 American Transplant Congress
Mid-Term Outcome of Donor Specific Antibody Positive Deceased Donor Kidney Transplantation with Peri-Transplant Desensitization
K. Osickova,¹ P. Hruba,² J. Slatinska,¹ A. Slavcev,² J. Fronek,² E. Honsova,² O. Viklicky.¹
¹Dept. of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; ²Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Donor specific HLA-antibodies (DSA) remain a large barrier to successful kidney transplantation and there is a limited knowledge about desensitization strategies in deceased donor programs.Anti…
2018 American Transplant Congress
High Fibre Diet Induces Donor Specific Kidney Allograft Tolerance in Mice
H. Wu,^1,2 T. Kwan,² Y. Loh,² C. Wang,² L. Macia,² S. Alexander,^2,3 S. Chadban.^1,2
¹Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; ²University of Sydney, Sydney, Australia; ³The Children Hospital at Westmead, Sydney, Australia.
Aim: To investigate the impact of high fibre (HF) diet or dietary supplementation with the short chain fatty acid sodium acetate (SA) on kidney allograft…
2018 American Transplant Congress
Intraoperative Blood Loss during Pediatric Liver Transplantation: A Single Center Experience
J. Kohler,¹ D. Yoeli,¹ R. Sigireddi,¹ R. Ackah,¹ M. Kueht,² T. Galvan,² R. Cotton,² A. Rana,² C. O'Mahony,² J. Goss.²
¹School of Medicine, Baylor College of Medicine, Houston, TX; ²Department of Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
Background: The aim of this study is to identify risk factors for massive intraoperative blood loss in pediatric liver transplant recipients and describe its impact…