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American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2018 American Transplant Congress

    Donor Liver Apoptosis is Associated with Early Allograft Dysfunction and Short-Time Graft Survival after Liver Transplantation

    Z. Guo, Z. Zhu, Y. Tang, S. Huang, Z. Zhang, X. He, G. Chen.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aims The aim of the study was to determine whether donor liver apoptosis is predictive for early allograft dysfunction (EAD) and graft survival after liver…
  • 2018 American Transplant Congress

    Interferon-b Promotes Regulatory T Cell (Treg) Induction and Prolongs Allograft Survival

    M. Fribourg,1 M. McGinty,2 A. Angeletti,2 M. Demir,2 S. Sealfon,1 P. Heeger,2 P. Cravedi.2

    1Neurology, Icahn School of Medicine at Mount Sinai, New York; 2Medicine, Translational Transplant Research Center, Recanati Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, New York.

    Background: Interferon-b (IFNb), a type I interferon with antiviral and pro-inflammatory activity, has been used as an immune modulatory treatment of multiple sclerosis (MS). The…
  • 2018 American Transplant Congress

    Lower Uric Acid Level after Kidney Transplantation Impact on Better Long-Term Allograft Outcomes

    D. Kim,1 H. Choi,2 Y. Jung,1 J. Lee,1 J. Lee,1 J. Lee,1 K. Huh,1 M. Kim,1 B. Kim,2 Y. Kim.1

    1Transplantation Surgery, Yonsei University Health System, Seoul, Korea; 2Nephrology, Yonsei University Health System, Seoul, Korea.

    BackgroundIt has been on debate that hyperuricemia was an independent risk factor for poor prognosis in kidney transplantation. Considering the link of UA with diabetes,…
  • 2018 American Transplant Congress

    Standard Induction Immunosuppression Interferes with the Role of Vascularized Bone Marrow in Vascularized Composite Allograft Protection

    N. Shockcor, E. Buckingham, W. Hassanein, A. Nam, S. Bartlett, R. Barth.

    Department of Surgery, University of Maryland School of Medicine, Baltimore, MD.

    Purpose: Clinical induction therapies have been demonstrated to interfere with the development of immunologic tolerance in experimental models. Vascularized bone marrow (VBM) has been demonstrated…
  • 2018 American Transplant Congress

    Hospital Readmission Patterns in the First Year after Kidney Transplantation: A Twelve-Year, Single-Center Experience

    M. Nguyen, C. Avila, J. Benedict, A. El-Hinnawi, A. Rajab, R. Pelletier, M. Henry, G. Bumgardner.

    Transplant Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

    Purpose: The majority of studies examining hospital readmissions (HR) after kidney transplantation (KT) focus on 30-day HR rates using multi-institutional data with non-uniform clinical protocols.…
  • 2018 American Transplant Congress

    Efficacy and Safety of a Single-Dose Rituximab for Prevention of Focal Segmental Glomerulosclerosis Recurrence after Kidney Transplant

    Y. Lu,1 J. Lyons,2 S. Tischer,2 K. Woodside,3 J. Park.2

    1Transplant Nephrology, University of Michigan, Ann Arbor, MI; 2Transplant Pharmacy, University of Michigan, Ann Arbor, MI; 3Transplant Surgery, University of Michigan, Ann Arbor, MI.

    Background: For patients with end stage renal disease (ESRD) due to primary focal segmental glomerulosclerosis (FSGS), there is a significantly increased risk for disease recurrence…
  • 2018 American Transplant Congress

    Graft Perfusion with Alvespimycin, an HSP90 Inhibitor, Suppresses Acute Allograft Rejection and Prolongs Graft Survival in Murine Heart Transplantation

    T. Tanaka, T. Maehana, N. Masumori.

    Department of Urology, Sapporo Medical University, Sapporo, Japan.

    Purpose: We have previously demonstrated that administration of a heat shock protein 90 (HSP90) inhibitor to recipients prolonged the allograft survival in murine skin and…
  • 2018 American Transplant Congress

    Kidney Transplantation from Uncontrolled Donation after Circulatory Death, Good Outcomes after Very Long Time

    M. Molina,1 J. Cabrera,2 E. Gonzalez,1 A. Hernandez,1 P. Natalia,1 A. Andres.1

    1Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain; 2Department of Nephrology, Hospital Evangelico, Montevideo, Uruguay.

    Introduction: Kidney transplantation (KT) is the best renal replacement therapy but the shortage of organ is the main limitation. Uncontrolled Donation after Circulatory Death (uDCD)…
  • 2018 American Transplant Congress

    Impacts of HBsAg Seropositive Status on Patient and Graft Survival after Kidney Transplantation in the Era of New Antiviral Therapy: A Meta-Analysis

    N. Leeaphorn,1 C. Thongprayoon,2 K. Sharma,2 A. Sakhuja,3 W. Cheungpasitporn.4

    1Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA; 2Department of Medicine, Bassett Medical Center, Cooperstown, NY; 3Department of Medicine, Mayo Clinic, Rochester, MN; 4Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS.

    BACKGROUND: An association between HBsAg seropositive status and increased mortality after kidney transplantation has been demonstrated in previous studies over the past decade. Although chronic…
  • 2018 American Transplant Congress

    Screening of RhoA/ROCK Inhibitors for the Ability to Prevent Chronic Rejection of Mouse Cardiac Allografts

    W. Chen, W. Chen, X. Li, R. Ghobrial, M. Kloc.

    THMRI, Houston, TX.

    Objectives. Chronic rejection of transplanted organs is a major obstacle in human organ transplantation. Although the mechanisms of chronic rejection are poorly understood it is…
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