Articles tagged "Graft survival"

2019 American Transplant Congress
Transition from Pediatric to Adult Care of Kidney Transplant Recipients: A Retrospective Analysis of a French Monocentric Cohort
M. Mazloum¹, M. Charbit², O. Aubert¹, D. Anglicheau¹, A. Scemla¹, R. Salomon², P. Krug², C. Legendre¹, R. Sberro-Soussan¹
¹Adult Nephrology and Renal Transplantation Department, Necker Hospital, Paris, France, ²Pediatric Nephrology and Renal Transplantation Department, Necker Hospital, Paris, France
*Purpose: Transition refers to the dynamic process in which the patient is oriented from pediatric to adult care. In the field of kidney transplantation, transition…
2019 American Transplant Congress
Microparticle Delivery to Lymph Nodes Induces Specific Suppression to Prolong Islet Survival
Y. Xiong¹, L. Tostanoski², C. Jewell³, J. Bromberg¹
¹Surgery, U. Maryland, Baltimore, MD, ²U.Maryland, Baltimore, MD, ³U. Maryland, College Park, MD
*Purpose: Microparticles (MP) loaded with peptide antigen plus other immune signals and delivered directly into lymph nodes (LN) can result in either proinflammatory or antiinflammatory…
2019 American Transplant Congress
The Degree of Glomerulosclerosis in Procurement Renal Biopsy and its Implications in Predicting Graft Outcomes in Marginal Donor Kidneys
W. Cheungpasitporn¹, W. Chon², E. Island², L. Cummings², J. Forster², N. Leeaphorn²
¹University of Mississippi Medical Center, Jackson, MS, ²Saint Luke's Health System, Kansas City, MO
*Purpose: Percentage of glomerulosclerosis (GS) is a major determinant for kidney discard. However, GS failed to consistently predict graft outcomes across studies in the literature.…
2019 American Transplant Congress
Lymphotoxin Beta Receptor in Lymphatic Endothelial Cells Regulates Treg Migration and Allograft Protection
V. Saxena, W. Piao, L. Li, C. M. Paluskievicz, Y. Xiong, T. Simon, J. S. Bromberg
U Maryland, Baltimore, MD
*Purpose: Lymphotoxin beta receptor (LTβR) mediated signaling in lymphatic endothelium cells (LEC) is important for migration of regulatory T cells (Treg) to afferent lymphatic vessels…
2019 American Transplant Congress
Regulatory T Cells Combined with Costimulation Blockade Prevent Rejection of Vascularized Composite Allografts
B. Oh¹, G. Furtmüller¹, M. Grzelak¹, L. Vuong², M. Iglesias¹, M. Fryer³, D. Cooney¹, R. Chen⁴, Y. Guo⁵, W. Lee¹, G. Raimondi¹, G. Brandacher¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Washington University in St. Louis School of Medicine, St. Louis, MO, ³The University of Massachusetts Medical School, Worcester, MA, ⁴Kaohsiung Medical Univerity Hospital, Kaohsiung, Taiwan, ⁵Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
*Purpose: Reconstructive transplantation represents a valid therapeutic option after devastating tissue loss. Routine clinical application, however, is hampered by the toxicity of long-term maintenance immunosuppression.…
2019 American Transplant Congress
Trimming the Fat?: Optimizing Utilization of Liver Allografts with Macrosteatosis >30% in Recipients with MELD Scores <35
J. A. Steggerda¹, M. B. Bloom¹, T. Todo², T. V. Brennan², N. N. Nissen², A. S. Klein², I. K. Kim²
¹Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA, ²Transplant Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA
*Purpose: Macrosteatosis (MaS) >30% in liver allografts has been associated with increased risk of primary non-function and poor graft survival. This study assesses the influence…
2019 American Transplant Congress
The Predictive Value Of Pre-transplant Biopsies For Short-term And Long-term Graft Function In Kidney Transplantation
H. Zhang¹, L. Liu¹, S. Yang², W. Chen², X. Chen¹, Y. Li², C. Wang¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: The predictive capacity of previous pre-transplant histologic scoring systems for short-term and long-term graft function in kidney transplantation has not been adequately validated.*Methods: Deceased…
2019 American Transplant Congress
Distribution And Outcomes Of Donor Right Kidneys In A National Paired Kidney Exchange Program
G. Roll¹, W. Irish², M. Cooper³, M. Ronin⁴, G. Hil⁵, A. D. Waterman⁶, D. B. Leeser²
¹UCSF, San Francisco, CA, ²ECU, Greenville, NC, ³Georgetown Univ, Washington, DC, ⁴NKR, Babylon, CA, ⁵NKR, Babylon, NY, ⁶UCLA and Terasaki Research Institute, Los Angeles, CA
*Purpose: Left living donor kidneys for transplant (txp) are preferred to right living donor kidneys for longer renal vein length which decreases technical difficulty of…
2019 American Transplant Congress
Normal Coronary Angiogram Pre-Transplant Does Not Predict Cardiac Events in Diabetic Kidney Transplant Recipients
F. Aziz, A. Mulay, M. Anders, S. Parajuli, D. Mandelbrot, A. Djamali
University of Wisconsin, Madison, WI
*Purpose: Cardiac events (CE) are a common cause of death in kidney transplant recipients. The aim of this study was to determine the risk factors…
2019 American Transplant Congress
Minimally Invasive Kidney Transplantation Using a Novel Intraoperative Cryogenic Circulatory Cooling Device
H. Dai, L. Peng, L. Song, Z. Tang, N. Wu, C. Fang, M. Nie, T. Li, Y. Zheng, X. Xie, S. Yu
Department of Urological Organ Transplantation,The Second Xiangya Hospital of Central South University, Changsha, China
*Purpose: Minimally invasive kidney transplantation (MIKT) has recently been introduced, however, an effective but inexpensive method to balance a minimal incision and reduced ischemia injury…