ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft function"

  • 2015 American Transplant Congress

    Right-Sided Kidney Transplants Are Associated With Early Graft Failure in the Setting of Delayed Graft Function

    I. Hall, W. Jiang, S. Kulkarni, C. Parkih.

    Yale University, New Haven, CT.

    Anatomical differences between right and left kidneys may affect transplant outcomes. We sought to determine if the right kidney (RK) tends to have worse graft…
  • 2015 American Transplant Congress

    Avoiding Futility in Simultaneous Liver-Kidney Transplantation (SLKT): Analysis of 331 Consecutively Listed Patients

    K. Lunsford, A. Bodzin, D. Reino, A. Zarrinpar, F. Kaldas, H. Gritsch, J. Veale, G. Lipshutz, D. Farmer, G. Danovitch, H. Yersiz, J. Hiatt, R. Busuttil, V. Agopian.

    Departments of Surgery, Urology, and Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA.

    Without well-established listing guidelines for SLKT, MELD prioritization of liver recipients with renal dysfunction potentially risks scarce renal allografts. We sought to evaluate short-term predictors…
  • 2015 American Transplant Congress

    Gender Differences in Kidney Transplant Delayed Graft Function Are Independent of Donor-Recpient Size Mismatch

    M. Levine,1 A. Thomasson,1 D. Aufhauser,1 R. Redfield,2 P. Abt,1 P. Reese.3

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Surgery, University of Wisconsin, Madison, WI; 3Medicine, University of Pennsylvania, Philadelphia, PA.

    Introduction: Superior female tolerance of ischemia reperfusion injury (IRI) relative to males has been described in animal models, but little human data are available to…
  • 2015 American Transplant Congress

    The Outcome of Carbapenemase-Producing Enterobacteriaceae (CPE) Infection in Adult Solid Organ Transplant Population at a University Teaching Hospital

    H. Sharma, A. El-Bakry, V. Venkat, S. Papachristos, P. Otilla, R. Dhanda, B. Forgacs, A. Tavakoli, R. Pararajasingam.

    Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.

    BACKGROUND:Over the last decade CPE infection has been reported globally and is now endemic in healthcare facilities in many countries. There has been no report…
  • 2015 American Transplant Congress

    Somatostatin (Eumedica®) Infusion Allows Modulating Graft Flows and Gradients in Liver Transplantation. Results of a Randomized, Double Blind, Placebo Controlled Trial

    R. Troisi,1 A. Croo,1 E. Codarin,3 E. De Wolf,1 J. Van Limmen,4 G. Antoniali,3 B. Heyse,4 L. De Baerdemaeker,4 I. Colle,5 G. Tell,3 M. Sainz-Barriga.1,2

    1General Hepatobiliary Surgery Liver Transplantation Service, Ghent University Hospital Medical School, Ghent, Belgium; 2Digestive Surgery & Liver Transplantation, University of Tours, Tours, France; 3Medical & Biological Sciences, University of Udine, Udine, Italy; 4Anesthesiology, Ghent University Hospital Medical School, Ghent, Belgium; 5Gastroenterology, Ghent University Hospital Medical School, Ghent, Belgium.

    Background: Somatostatin (SST) infusion decrease portal pressure in acute variceal bleeding in cirrhotic patients. Despite liver transplantation (LTx), recipients with portal hypertension (PHT) display different…
  • 2015 American Transplant Congress

    Combination of Clinical and Genetic Factors for Delayed Kidney Graft Function Prediction

    A. Goncalves-Primo,1,2 E. Campos,1,2 J. Medina-Pestana,2,3 H. Tedesco-Silva,3 M. Gerbase-DeLima.1,2

    1Immunogenetics Institute, AFIP, São Paulo, SP, Brazil; 2Universidade Federal de São Paulo, São Paulo, SP, Brazil; 3Hospital do Rim e Hipertensão- FOR, São Paulo, SP, Brazil.

    In this study we sought to determine the risk for delayed graft function (DGF) in kidney transplants (Tx) with deceased donors (DD) through the analysis…
  • 2015 American Transplant Congress

    Part II: Rates and Determinants of Progression for De Novo Donor-Specific Antibody Mediated Kidney Allograft Injury

    C. Wiebe,1,2 I. Gibson,3 D. Pochinco,2 P. Birk,4 T. Blydt-Hansen,4 J. Ho,1,5 M. Karpinski,1 A. Goldberg,4 L. Storsley,1 D. Rush,1 P. Nickerson.1,2,5

    1Medicine, University of Manitoba, Winnipeg, MB, Canada; 2Immunogenetics, Diagnostic Services of Manitoba, Winnipeg, MB, Canada; 3Pathology, University of Manitoba, Winnipeg, MB, Canada; 4Pediatric and Child Health, University of Manitoba, Winnipeg, MB, Canada; 5Immunology, University of Manitoba, Winnipeg, MB, Canada.

    The development of de novo donor-specific antibody (dnDSA) is an independent predictor of allograft loss in renal transplantation. Rates and determinants of clinical pathologic progression…
  • 2015 American Transplant Congress

    Switching from Tacrolimus to Low-Dose Cyclosporine A Preserves Allograft Function in Presumptive and Definitive Polyomavirus-Associated Nephropathy

    G. Huang, C.-X. Wang, J.-G. Fei, J. Qiu, S.-X. Deng, J. Li, G.-D. Chen, Q. Fu, R.-H. Deng, L.-Z. Chen.

    Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Switching from tacrolimus(Tac) to low-dose cyclosporine A(CsA) is recommended for preventing BK virus-associated nephropathy(BKVAN) and preserving allograft function in BKVAN patients, but systematic evaluations were…
  • 2015 American Transplant Congress

    Assessment of Renal Function in Kidney Transplant Recipients Through Therapeutic Drug Monitoring of Vancomycin

    A. Thamer, N. Elias, C. Varughese, T. Gift, J. Fishman, S. Shao.

    Massachusetts General Hospital, Boston, MA.

    Background: Determining the dose of renally eliminated drugs such as vancomycin in kidney transplant recipients is often challenging due to unclear tools to assess renal…
  • 2015 American Transplant Congress

    Inhibition of mTOR Modulates SLPI Expression: A Potential Role in Kidney Transplant Patients

    N. Ambrosi,1 A. Dotta,2 C. Pizarro,2 D. Guerrieri,1 A. Gonzalez,2 C. Leiva,2 L. Leon,2 J. Mendiberri,3 M. Rial,2 C. Incardona,4 E. Chuluyan,1 D. Casadei.2

    1CEFYBO, UBA, Buenos Aires, Argentina; 2Fundacion 3er Milenio, INBA, Buenos Aires, Argentina; 3UNICEN, Olavarria, Argentina; 4Fundación GADOR, Buenos Aires, Argentina.

    Secretory leukocyte protease inhibitor (SLPI) is a serine protease inhibitor secreted by inflammatory and epithelial cells. It functions as an endogenous immunomodulatory, with antiinflammatory and…
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