Session Time: 5:30pm-6:30pm
Presentation Time: 5:30pm-6:30pm
Location: Exhibit Hall E
Allograft biopsy is the definitive diagnostic methods for evaluation of renal dysfunction, but there is always the risk of complications. Efforts to develop a notable alternative to biopsy have continued. The aim of this study was to explore the clinical implication of acoustic radiation force impulse (ARFI) technique.
Patients and Methods
A total of 91 patients who received a living donor renal transplantation between September 2010 and January 2013 were included in this prospective study. We measured the shear wave velocity (SWV) by ARFI at baseline and at predetermined time points (1 week, 6 months, and 12 months after transplantation). Protocol biopsies were performed at 12 months.
Instead of reflecting renal fibrosis, the SWV value was related to the time elapsed after transplantation. Mean SWV value increased continuously during 1 year (p<0.001). In addition, there was no correlation between SWV value and serum creatinine in mixed model analysis considering the time of inspection. The changes of SWV showed different pattern according to the kidney weight to bodyweight ratio (KW/BW). The mean SWV of patients with KW/BW <3.5 g/kg was continuously increasing for 12 months, on the other hand, that of KW/BW ≥3.5 g/kg group was decreasing after 6 months.
SWV value was related to the time elapsed after transplantation. There was no significant correlation between SWV value with renal fibrosis or renal dysfunction. Hemodynamic factors could be impact on the SWV value.
To cite this abstract in AMA style:Lee J, Lee J, Lee A-l, Ma B, Oh Y, Huh K, Kim M, Kim S, Kim Y, Joo D. Acoustic Radiation Force Impulse Measurement in Renal Transplantation [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/acoustic-radiation-force-impulse-measurement-in-renal-transplantation/. Accessed June 5, 2020.
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