2019 American Transplant Congress
Pharmacological Mobilization of Host Stem Cells Prevents Delayed Graft Function Following Kidney Transplantation in Rats
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Delayed graft function (DGF) caused by ischemia-reperfusion injury (IRI) is an early complication that occurs in nearly a quarter of all deceased-donor kidneys and…2019 American Transplant Congress
Role of Mitochondria, Metabolism and Inflammation: Pathways Influencing Short Term Outcomes Post-Renal Transplantation
*Purpose: Preconditioning of donor kidneys and clinical assessment for need of dialysis early post-transplant vary per each case and are crucial for improving transplant outcomes.…2019 American Transplant Congress
Kidney Transplants Following Donation after Circulatory Death and Donation after Brain Death Have Similar Early Outcomes
*Purpose: Donation after circulatory death (DCD) is common in the US, comprising 18.3% of the deceased donor pool in 2017. Recipient outcomes following DCD kidney…2019 American Transplant Congress
Mesangiopathic Glomerulonephritis in Kidney Transplants
*Purpose: Describe higher than anticipated prevalence of Mesangiopathic Glomerulonephritis on surveillance biopsies.*Methods: Review of all surveillance biopsies from September 2014 through September 2018 for presence…2019 American Transplant Congress
Protocol Cidofovir for Refractory Polyomavirus Associated Nephropathy in Kidney Transplant Recipients
University of Maryland Medical Center, Baltimore, MD
*Purpose: Dose-limiting nephrotoxicity has historically precluded the use of cidofovir for polyomavirus associated nephropathy (PVAN). With incidence of BK viremia in kidney transplant recipients increasing…2019 American Transplant Congress
Fasting Glood Glucose: A Simple and Reliable Marker to Predict Late Pancreas Graft Failure
*Purpose: Causes of early post-transplant pancreas graft failure are well identified. Indeed, this is not the case after the first year. We searched factors which…2019 American Transplant Congress
Fifteen Year Outcomes in the Astellas Double Blind Randomized Controlled Trial (RCT) Comparing Early Corticosteroid Withdrawal (CSWD) and Long-Term Corticosteroid Therapy Continuation (CCS) in Kidney Transplantation
*Purpose: To evaluate long-term outcomes among participants in the original multi-center RCT initiated in 1999 (Woodle et al, Annals of Surgery, 2008), and to demonstrate…2019 American Transplant Congress
Distinct Delayed Classical Complement Pathway Activation Highlights Transition of Ischemic Acute Kidney Injury to Chronic Kidney Disease with Interstitial Fibrosis/Tubular Atrophy
Comprehensive Transplant Center, Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: Ischemia reperfusion Injury (IRI)-induced AKI of the renal allograft frequently leads to delayed graft function (DGF). Patients with DGF suffer from prolonged hospitalization with…2019 American Transplant Congress
Transfer of Healthy Mitochondria in Established Ischemic Injury Reduces Progression to Interstitial Fibrosis and Tubular Atrophy
*Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Therapeutic interventions that target to…2019 American Transplant Congress
Alemtuzumab versus Anti-Thymocyte Globulin Induction in the Setting of Immediate Post-Renal Transplant Acute Tubular Necrosis in an Urban, Minority Patient Population
University of Illinois at Chicago, Chicago, IL
*Purpose: Post-renal transplant (RTx) delayed graft function (DGF) or slow graft function (SGF) increase the risk of rejection and impair allograft function. Lymphocyte depleting induction…
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