2018 American Transplant Congress
Facial Allotransplantation: An Early Look at OPTN Data
Craniofacial Vascularized Composite Allograft (VCA) transplantation is a developing area in the field of transplantation. Thirteen craniofacial transplants have been performed in the US since…2018 American Transplant Congress
Antiproteinuric Effect of Spironolactone in Renal Transplantation: Effectiveness and Clinical Outcomes
University of Campinas, Campinas, Sao Paulo, Brazil.
Background: aldosterone is involved in development of fibrosis in kidney transplantation. Blockade of aldosterone receptor appears to be effective in treatment for chronic allograft dysfunction,…2018 American Transplant Congress
Relationship between Living Kidney Donor Follow-Up GFR and Recipient Graft Loss
In living kidney transplantation, it is reasonable to believe a donated kidney's function would be associated with the function of the donor's remaining kidney. Indeed,…2018 American Transplant Congress
The Likelihood of Re-Transplantation in Patients Undergoing Allograft Nephrectomy
Introduction: transplant nephrectomy (NX) is a known cause of allosensitisation after graft failure. As yet, there is no consensus for the management of the patient…2018 American Transplant Congress
Acute Murine CMV Infection Results in Loss of Intragraft CD73HIFR4HIPD1+ CD4 T Cells and Graft Rejection in Previously Tolerant Recipients
Background: Transplantation tolerance in human recipients has been achieved in recent trials. Nevertheless, the impact of highly prevalent and clinically relevant cytomegalovirus (CMV) infection on…2018 American Transplant Congress
Scoring Transplant Glomerulopathy Using Morphometry: Correlation with Banff Criteria
William J.von Liebig Transplant Center, Mayo Clinic, Rochester, MN.
Background: Transplant glomerulopathy (TG) is a prognostic marker for graft survival. Still, scoring TG using the Banff cg-score remains a challenge and no assessments in…2018 American Transplant Congress
The Association between Transplant Glomerulopathy and Graft Outcomes among Patients Undergoing Kidney Transplantation: Results of a Meta-Analysis
Transplant glomerulopathy (TG) can lead to irreversible kidney damage. TG is recognized as a surrogate marker for poor outcomes, including graft failure and loss among…2018 American Transplant Congress
Linking Donor Ischemia Reperfusion Injury (IRI) to Costimulatory Blockade Resistant Murine Heart Graft Rejection through Complement-Initiated Necroptosis
We previously showed that prolonged cold ischemic storage (CIS) of donor B6 hearts results in complement dependent, CTLA4Ig-resistant rejection in BALB/c recipients. In this system,…2018 American Transplant Congress
Title: Donor-Derived Cell Free DNA Predicts Development of Clinically Significant Changes in Donor Specific Antibody Following Kidney Transplant
Background: Recently, high immunologic risk patients comprise a significant percentage of the total adult renal transplants performed yearly. Surveillance management of these patients and interpretation…2018 American Transplant Congress
Standard Induction Immunosuppression Interferes with the Role of Vascularized Bone Marrow in Vascularized Composite Allograft Protection
Department of Surgery, University of Maryland School of Medicine, Baltimore, MD.
Purpose: Clinical induction therapies have been demonstrated to interfere with the development of immunologic tolerance in experimental models. Vascularized bone marrow (VBM) has been demonstrated…
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