Articles tagged "Graft failure"

2020 American Transplant Congress
Transitional B Cell Cytokines for the Early Prediction of Long-Term Renal Allograft Decline
A. Cherukuri¹, A. Salama², A. Sharma¹, R. Mehta¹, S. Hariharan¹, D. Rothstein¹
¹Starzl Transplantation Institute, UPMC, Pittsburgh, PA, ²UCL, London, London, United Kingdom
*Purpose: Early prediction of allograft loss using potentially modifiable risk factors is vital for conceiving novel therapeutic interventions to improve outcomes.*Methods: In this prospective, multicenter…
2020 American Transplant Congress
Vira-ome: A Tool for an Unbiased Plasma Virome Analysis of SOT Recipients from Cell-Free DNA Sequences
R. Sinha, E. Bixler, J. Grantham, M. Altrich, S. Kleiboeker
R&D, Viracor-Eurofins, Lee's Summit, MO
*Purpose: Blood virome of healthy individuals is frequently predominated by member of families such as Herpesvirus, Anellovirus and Polyomaviridae. The viral load of commensal species…
2020 American Transplant Congress
The Application of Hypothermic Machine Perfusion in Kidney Transplantation from Delay Graft Function High Risk Donor
Y. Li, X. Hu, G. Chen, C. Ding, W. Xue
Kidney Transplantation Department, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
*Purpose: To investigate the clinical effect of the hypothermic machine perfusion (HMP) method on renal transplantation from high risk donation after citizen death (DCD) and…
2020 American Transplant Congress
The Influence of the Donor Kidney Weight to Recipient Body Weight Ratio on Long-Term Renal Graft Outcomes
S. Yang¹, J. Lee¹, Y. Jung², B. Kim³, M. Kim¹, S. Kim¹, Y. Kim¹, K. Huh¹
¹Department of Transplantation Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, ²Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, ³Department of Nephrology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of
*Purpose: To study the impact of the relative donor kidney size on long-term graft function and survival, we investigated the living donor renal transplants outcomes.*Methods:…
2020 American Transplant Congress
Eplet Mismatch Not Correlated with Antibody Mediated Rejection or Allograft Loss Among Kidney Transplant Recipients with De Novo Donor Specific Antibody
A. Basu¹, W. Jiqiu², A. Bentall², M. Gandhi², B. Dukek², N. Henderson², C. Schinstock²
¹Emory Healthcare, Atlanta, GA, ²Mayo Clinic, Rochester, MN
*Purpose: Eplet mismatches are associated with development of de novo DSA (dnDSA) in kidney transplant recipients. However, it remains unclear how the degree of eplet…
2020 American Transplant Congress
Antibiotic Pretreatment Alleviates Liver Transplant Damage by Modulating the Composition of Commensal Microbiota
K. J. Dery, S. Kageyama, H. Hirao, K. Kadono, H. Kojima, R. W. Busuttil, J. W. Kupiec-Weglinski
Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: The human intestinal microbiome contains more than 100 trillion commensal microorganisms, exceeding the number of cells in the human body by 10-fold. Although recent…
2020 American Transplant Congress
The Accuracy of the ICD-10 Diagnostic Codes for Kidney Transplant Rejection and Failure
D. Massicotte-Azarniouch¹, M. Sood², D. Fergusson³, M. Chassé⁴, A. Tinmouth⁵, G. Knoll²
¹Medicine, University of Ottawa, Ottawa Hospital, Ottawa, ON, Canada, ²Medicine, University of Ottawa, Ottawa Hospital Research Institute, Ottawa, ON, Canada, ³Clinical Epidemiology, University of Ottawa, Ottawa Hospital Research Institute, Ottawa, ON, Canada, ⁴Medicine, University of Montreal, Ottawa, ON, Canada, ⁵Hematology, University of Ottawa, Ottawa Hospital Research Institute, Ottawa, ON, Canada
*Purpose: Clinical research requires that diagnostic codes captured from routinely collected health administrative data accurately identify individuals with a disease. In this study, we examined…
2020 American Transplant Congress
Transplant and Cardiovascular Outcomes in Renal Transplant Recipients with Different Pre-Transplant Cardiovascular Risk
G. Hsu¹, T. M. Sparkes¹, B. N. Reed², S. E. Gale¹, B. R. Ravichandran¹
¹University of Maryland Medical Center, Baltimore, MD, ²University of Maryland School of Pharmacy, Baltimore, MD
*Purpose: Renal transplant patients have higher cardiovascular (CV) risk compared to their peers. Pre-transplant CV risk factors may be amplified post-transplant, but little is known…
2020 American Transplant Congress
Sequential Protocol Biopsies Post-Liver Transplant from Donors with Moderate Macrosteatosis: What Happens to the Fat?
K. Croome, D. Livingston, C. Taner, R. Nakhleh
Mayo Clinic Jacksonville, Jacksonville, FL
*Purpose: The number of steatotic deceased donor livers encountered has continued to rise as a result of the obesity epidemic. Little is known about the…
2020 American Transplant Congress
Evaluating the Effect of HCV Status on the KDPI in the Era of DAA Therapy
J. Husson¹, S. Curreli², B. Ravichandran³, E. Wilson⁴
¹Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, ²Institute of Human Virology, Baltimore, MD, ³University of Maryland Medical Center, University of Maryland School of Pharmacy, Baltimore, MD, ⁴Institue of Human Virology, University of Maryland School of Medicine, Baltimore, MD
*Purpose: The association between KDPI and kidney graft outcomes is limited in the era of DAA therapy.*Methods: We analyzed adult renal transplants, at the University…