2019 American Transplant Congress
Return to Work after Sick Leave in Kidney Transplant Recipients: A 365-Day Cohort of the Japan Academic Consortium of Kidney Transplantation (JACK) Study
*Purpose: They said that kidney transplantation was better than dialysis about patient survival and quality of life. However, there have been no large-scale Japanese studies…2019 American Transplant Congress
Impact Of Aggressive Utilization Of Liver Allografts On Outcomes
Baylor College of Medicine, Houston, TX
*Purpose: Many risk factors impact outcomes for liver transplantation, among them are factors that are particular to individual transplant centers or center-level factors. Our aim…2019 American Transplant Congress
Liver Circle-Based Allocation: LSAM Modeling Results
*Purpose: On June 25, 2018, the OPTN Board of Directors (BOD) directed the Liver and Intestinal Organ Transplantation Committee to propose changes to policy removing…2019 American Transplant Congress
Pediatric Liver Transplantation during the Opioid Epidemic: UNOS Analysis of Organ Availability and Outcomes
*Purpose: The opioid epidemic has been largely responsible for the 3-fold increase in deaths due to drug overdose over the last 15 years. Whether this…2019 American Transplant Congress
Kidney & Pancreas Transplant Waitlist Management – A Tiered System Approach
Transplant, UCI Health, Orange, CA
*Purpose: Developed and implemented an innovative kidney & pancreas transplant waitlist management system in order to more effectively and efficiently re-evaluate patients on a transplant…2019 American Transplant Congress
Ablation of Interferon Regulatory Factor 4 in T Cells Induces “Memory” of Transplant Tolerance That is Irreversible by Immune Checkpoint Blockade
*Purpose: Achieving alloantigen-specific transplant tolerance through ablation of interferon regulatory factor 4 in T cells*Methods: 1. Irf4fl/flCD4-Cre recipients were first transplanted with BALB/c hearts and…2018 American Transplant Congress
Early Evolution and Pathologic Characteristics of Treg-Rich Organized Lymphoid Structures (TOLS) Associated with Immunological Tolerance in Accepted Mouse Kidney Allografts
Introduction: The kidney is pro-tolerogenic by mechanisms as yet unknown. In mice, tolerance of kidney allografts can occur spontaneously in certain strain combinations, such as…2018 American Transplant Congress
Endoplasmic Reticulum Stress Sensor IRE1α Deficiency Promotes Infiltrating Macrophage Polarization and Induces Long-Term Renal Allograft Acceptance in Mice
Objective: Macrophage is involved in the pathogenesis of I/R injury and allograft rejection. However, the mechanisms underlying this is vastly unknown. This study aims to…2018 American Transplant Congress
Ablation of IRF4 Induces Transplant Tolerance by Driving Intrinsic T Cell Dysfunction
How transplant rejection is regulated on a transcriptional level remains unclear. We found that T cell-specific conditional knockout (cKO) of the transcription factor IRF4 in…2018 American Transplant Congress
Skeletons in the Closet? An Insight into Donor Liver Discards in the US
Weill Cornell Medicine, NY, NY.
Background Liver discards are poorly investigated. Among these discarded livers are potentially useable grafts that could save the lives of many of the 2500-3000 who…
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