Articles tagged "Graft acceptance"

2019 American Transplant Congress
Patient Perspectives of Informed Consent for Deceased Donor Organ Intervention Research
E. Gordon¹, B. Knopf¹, A. Mussell², C. Phillips², R. Veatch³, P. Abt², P. Reese²
¹Northwestern University, Chicago, IL, ²University of Pennsylvania, Philadelphia, PA, ³Georgetown University, Washington DC, DC
*Purpose: Interventions on deceased donors or their organs hold promise for increasing the quantity and quality of organs for transplantation by minimizing organ injury and…
2019 American Transplant Congress
Plasmacytoid Dendritic Cell-Mediated Graft Prolongation Requires microRNA-181 and Semaphorin 4a
J. Harden, X. Qi, A. Lau, S. Krams
Stanford Univ School of Med, Stanford, CA
*Purpose: Dendritic cells (DCs) are antigen-presenting cells (APCs) important for initiating and coordinating the immune response. Plasmacytoid dendritic cells (pDCs) are a subset of DCs…
2019 American Transplant Congress
Conceptual Extension of SNP Based Abundance Profiling to Infer Donor Derived Cell-Free DNA Fraction as an Indication of Organ Rejection
R. Sinha, K. Mickey, J. Grantham, M. Wissel, M. Altrich, S. Kleiboeker
R&D, Viracor-Eurofins, Lee's Summit, MO
*Purpose: Rejection is a major post-transplant complication for organ transplant recipients. Biopsy remains the standard to diagnose rejection, but other non-invasive methods, such as transcript…
2019 American Transplant Congress
AMD3100 (Plerixafor) as a Single-Dose Stem Cell Mobilizing Agent in Vascularized Composite Tissue Allograft (VCA) Transplantation in a Canine DLA-Mismatch Model
B. Swearingen¹, S. Graves², R. Storb², D. W. Mathes¹
¹University of Colorado School of Medicine, Aurora, CO, ²Fred Hutchinson Cancer Research Center, Seattle, WA
*Purpose: Vascularized Composite Allograft (VCA) transplantation is a clinical reality but limited by toxicities of chronic immunosuppression and rejection. Current clinical tolerance protocols rely on…
2019 American Transplant Congress
Impact of Discards for Living Donor Kidney Transplantation in Center Transplant Program
H. Villafuerte¹, E. De Sousa-Amorim², L. Peri³, M. Musquera³, E. Palou⁴, M. Lozano⁵, J. Cid⁵, J. Martorell⁴, J. M. Campistol², F. Oppenheimer², F. Diekmann², I. Revuelta²
¹Department of Nephrology, Hospital Clinic Lozano Blesa, Zaragoza, Spain, ²Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, ³Department of Urology, Hospital Clinic, Barcelona, Spain, ⁴Department of Immunology, Hospital Clinic, Barcelona, Spain, ⁵Department of Apheresis, Hospital Clinic, Barcelona, Spain
*Purpose: New and coming information about the risk of living kidney donors make the effort to study very carefully the option of living kidney donor…
2019 American Transplant Congress
Meld Score / Grwr Ratio (meldgr) Can Predict Surgical Outcomes And Prognosis Of The Recipients In Adult-to-adult Living Donor Liver Transplantation
A. Tanemura, A. Hayasaki, T. Fujii, Y. Iizawa, H. Kato, Y. Murata, N. Kuriyama, Y. Azumi, M. Kishiwada, S. Mizuno, M. Usui, H. Sakurai, S. Isaji
Hepatobiliary Pancreatic and Transplant Surgery, Mie University, Tsu, Japan
*Purpose: In living donor liver transplantation (LDLT), various risk factors have been identified among both recipient and donor factors, such as Model for End-Stage Liver…
2019 American Transplant Congress
Return to Work after Sick Leave in Kidney Transplant Recipients: A 365-Day Cohort of the Japan Academic Consortium of Kidney Transplantation (JACK) Study
K. Miyake¹, M. Okumi¹, K. Unagami², Y. Kakuta¹, M. Furusawa¹, K. Omoto³, T. Shimizu³, M. Endo⁴, H. Ishida², K. Tanabe¹
¹Urology, Tokyo Women's Medical University, Sinjuku, Japan, ²Organ Transplant Medicine, Tokyo Women's Medical University, Sinjuku, Japan, ³Urology, Toda Chuo General Hospital, Saitama, Japan, ⁴Public Health, Juntendo University, Bunkyo, Japan
*Purpose: They said that kidney transplantation was better than dialysis about patient survival and quality of life. However, there have been no large-scale Japanese studies…
2019 American Transplant Congress
Impact Of Aggressive Utilization Of Liver Allografts On Outcomes
A. Rana, M. Kueht, N. Galvan, R. Cotton, C. O'Mahony, J. Goss
Baylor College of Medicine, Houston, TX
*Purpose: Many risk factors impact outcomes for liver transplantation, among them are factors that are particular to individual transplant centers or center-level factors. Our aim…
2019 American Transplant Congress
Liver Circle-Based Allocation: LSAM Modeling Results
D. Schladt¹, T. Weaver¹, J. Pyke¹, A. Herreid¹, B. Thompson¹, B. Kasiske¹, J. Snyder¹, W. Kim², J. Lake³, A. Israni¹, J. Heimbach⁴
¹SRTR, Minneapolis, MN, ²Stanford Univ, Stanford, CA, ³Univ of Minnesota, Minneapolis, MN, ⁴Mayo Clinic, Rochester, MN
*Purpose: On June 25, 2018, the OPTN Board of Directors (BOD) directed the Liver and Intestinal Organ Transplantation Committee to propose changes to policy removing…
2019 American Transplant Congress
Pediatric Liver Transplantation during the Opioid Epidemic: UNOS Analysis of Organ Availability and Outcomes
J. Chu¹, J. Franke², C. Almy¹, R. Annunziato², R. Arnon¹
¹Recanati/Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, New York, NY, ²Psychology, Fordham University, New York, NY
*Purpose: The opioid epidemic has been largely responsible for the 3-fold increase in deaths due to drug overdose over the last 15 years. Whether this…

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