ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft acceptance"

  • 2019 American Transplant Congress

    Meld Score / Grwr Ratio (meldgr) Can Predict Surgical Outcomes And Prognosis Of The Recipients In Adult-to-adult Living Donor Liver Transplantation

    A. Tanemura, A. Hayasaki, T. Fujii, Y. Iizawa, H. Kato, Y. Murata, N. Kuriyama, Y. Azumi, M. Kishiwada, S. Mizuno, M. Usui, H. Sakurai, S. Isaji

    Hepatobiliary Pancreatic and Transplant Surgery, Mie University, Tsu, Japan

    *Purpose: In living donor liver transplantation (LDLT), various risk factors have been identified among both recipient and donor factors, such as Model for End-Stage Liver…
  • 2019 American Transplant Congress

    Return to Work after Sick Leave in Kidney Transplant Recipients: A 365-Day Cohort of the Japan Academic Consortium of Kidney Transplantation (JACK) Study

    K. Miyake1, M. Okumi1, K. Unagami2, Y. Kakuta1, M. Furusawa1, K. Omoto3, T. Shimizu3, M. Endo4, H. Ishida2, K. Tanabe1

    1Urology, Tokyo Women's Medical University, Sinjuku, Japan, 2Organ Transplant Medicine, Tokyo Women's Medical University, Sinjuku, Japan, 3Urology, Toda Chuo General Hospital, Saitama, Japan, 4Public Health, Juntendo University, Bunkyo, Japan

    *Purpose: They said that kidney transplantation was better than dialysis about patient survival and quality of life. However, there have been no large-scale Japanese studies…
  • 2019 American Transplant Congress

    Impact Of Aggressive Utilization Of Liver Allografts On Outcomes

    A. Rana, M. Kueht, N. Galvan, R. Cotton, C. O'Mahony, J. Goss

    Baylor College of Medicine, Houston, TX

    *Purpose: Many risk factors impact outcomes for liver transplantation, among them are factors that are particular to individual transplant centers or center-level factors. Our aim…
  • 2019 American Transplant Congress

    Liver Circle-Based Allocation: LSAM Modeling Results

    D. Schladt1, T. Weaver1, J. Pyke1, A. Herreid1, B. Thompson1, B. Kasiske1, J. Snyder1, W. Kim2, J. Lake3, A. Israni1, J. Heimbach4

    1SRTR, Minneapolis, MN, 2Stanford Univ, Stanford, CA, 3Univ of Minnesota, Minneapolis, MN, 4Mayo Clinic, Rochester, MN

    *Purpose: On June 25, 2018, the OPTN Board of Directors (BOD) directed the Liver and Intestinal Organ Transplantation Committee to propose changes to policy removing…
  • 2019 American Transplant Congress

    Pediatric Liver Transplantation during the Opioid Epidemic: UNOS Analysis of Organ Availability and Outcomes

    J. Chu1, J. Franke2, C. Almy1, R. Annunziato2, R. Arnon1

    1Recanati/Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 2Psychology, Fordham University, New York, NY

    *Purpose: The opioid epidemic has been largely responsible for the 3-fold increase in deaths due to drug overdose over the last 15 years. Whether this…
  • 2019 American Transplant Congress

    Kidney & Pancreas Transplant Waitlist Management – A Tiered System Approach

    H. L. Busch

    Transplant, UCI Health, Orange, CA

    *Purpose: Developed and implemented an innovative kidney & pancreas transplant waitlist management system in order to more effectively and efficiently re-evaluate patients on a transplant…
  • 2019 American Transplant Congress

    Ablation of Interferon Regulatory Factor 4 in T Cells Induces “Memory” of Transplant Tolerance That is Irreversible by Immune Checkpoint Blockade

    H. Zhang1, J. Wu2, D. Zou3, W. Chen3

    1The second Xiangya Hospital, Changsha, China, 2Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 3Immunobiology & Transplant Science Center, Houston Methodist Research Institute, Houston, TX

    *Purpose: Achieving alloantigen-specific transplant tolerance through ablation of interferon regulatory factor 4 in T cells*Methods: 1. Irf4fl/flCD4-Cre recipients were first transplanted with BALB/c hearts and…
  • 2019 American Transplant Congress

    B Cell-Specific IRE1a Deficiency Protects Renal Allografts from Rejection via Inhibition of Donor-Specific Antibodies and Induction of B Regulatory Cells

    L. Qiu1, J. Wang1, X. Yeap1, D. Fang2, Z. J. Zhang1

    1Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL, 2Department of Pathology, Northwestern University, Chicago, IL

    *Purpose: Despite the progress in immunosuppressive regimens, antibody-mediated rejection remains a major contributor to renal allograft loss in recipients with donor-specific antibodies (DSA). IRE1a, an…
  • 2019 American Transplant Congress

    Superiority of Donor-Specifically vs. Polyclonally Expanded Regulatory T Cells in Controlling Graft Rejection in the NSG Mouse Human Skin Graft Model

    J. H. Voss1, F. Zheng1, M. D. Jendrisak2, J. R. Leventhal1, Z. J. Zhang1, J. M. Mathew1

    1Surgery – Comprehensive Transplant Center, Northwestern University, Chicago, IL, 2Gift of Hope Organ & Tissue Donor Network, Itasca, IL

    *Purpose: Naturally occurring CD4+CD25highFOXP3+ Regulatory T cells (Tregs) function as mediators of immune homeostasis. So, they are beginning to be utilized for controlling hyper-immunity and…
  • 2019 American Transplant Congress

    Machine Perfusion Allows Use of High KDPI and Prolonged Cold Ischemia Time in Deceased Donors: A Single Center Effort to Decrease Discard Rates

    M. Ortigosa-Goggins, J. Gaynor, A. Mattiazzi, J. Figueiro, G. Burke, G. Ciancio, G. Guerra

    Miami Transplant Institute, University of Miami, Miami, FL

    *Purpose: Discard rates of deceased donor kidney transplants(DDKT)rises as the kidney donor profile index(KDPI)increases,and approaches 60%for KDPI of >85%.Pulsatile machine perfusion(MP)allows use of kidneys with…
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