Articles tagged "Graft acceptance"

2020 American Transplant Congress
Cardiac Allograft Tolerance Can be Achieved in Non-Human Primates via Transient Mixed Hematopoietic Chimerism and Erythropoietin Administration
K. Ahrens¹, J. M. O¹, W. Sommer², J. Morrissette¹, D. Becerra¹, P. M. Patel¹, A. Dehnadi¹, T. Costa¹, I. M. Hanekamp¹, J. S. Allan³, P. Cravedi⁴, P. S. Heeger⁴, G. Benichou¹, J. C. Madsen⁵
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, ³Center for Transplantation Sciences, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, ⁴Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, ⁵Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: In non-human primates (NHPs), a mixed chimerism-based conditioning protocol results in kidney transplant tolerance and combined kidney and heart allograft tolerance. Previous work showed…
2020 American Transplant Congress
Gross Morphological Score for Deceased Donor Kidneys Can Predict Delayed Graft Function in Kidney Transplant Recipients
M. Mandurah, M. A. Levine, A. Sener, P. Luke
Department of Kidney Transplantation, London Health Sciences Center, London, ON, Canada
*Purpose: Both microscopy and kidney donor profile index (KDPI) scoring systems have been used to predict kidney transplant outcomes. Utilizing gross renal morphology, we designed…
2020 American Transplant Congress
Dual Kidney Transplantation Offers a Safe and Effective Way to Use Kidneys from Deceased Donors Older Than 70 Years
K. Lee, J. Park, S. Cha, M. Kim
Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: Dual kidney transplantation (DKT) offers a way to extend the use of kidneys from expanded criteria donors (ECDs). Here, we compared the outcomes of…
2020 American Transplant Congress
The Impact of Occult Graft Fibrosis on Clinical Outcomes in Human Liver Transplant Recipients
H. Hirao¹, T. Ito¹, B. V. Naini¹, K. Nakamura², S. Kageyama¹, K. Kadono¹, H. Kojima¹, K. J. Dery¹, S. Younan¹, F. M. Kaldas¹, R. W. Busuttil¹, J. W. Kupiec-Weglinski¹
¹UCLA, Los Angeles, CA, ²Kyoto University, Kyoto, Japan
*Purpose: Although liver transplantation (LT) has become a standard therapy for end-stage liver disease, early allograft dysfunction (EAD) and graft rejection remain serious unsolved problems.…
2020 American Transplant Congress
Geographic Discard Disparities of Liver Allografts
P. I. Kenny Jr¹, A. Rana², J. Vierling²
¹Medical Student, Baylor College of Medicine, Houston, TX, ²Baylor College of Medicine, Houston, TX
*Purpose: The aim of this study is to demonstrate the significant geographic disparity in liver allograft discard.*Methods: Using the OPTN Diseased Donor Network database, we…
2020 American Transplant Congress
Predicting Kidney Allograft Discard: The Kidney Discard Risk Index
M. B. Price, M. Joshi, T. Zhang, J. Vierling, T. Galvan, R. Cotton, C. O'Mahony, J. Goss, A. Rana
Michael E. DeBakey Department of Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: The disparity between the supply and demand for kidney allografts is exacerbated by an 18.9% discard rate. It is our aim to determine predictors…
2020 American Transplant Congress
Report of Organ Offers Linked with Instant Messaging Data Provides a Basis for Quality Improvement
E. Pahl
Health Informatics, University of Iowa, Iowa City, IA
*Purpose: Thousands of viable organs are discarded every year with incorrect or inappropriate reasons for declination. One limitation on the accessibility of organ transplantation is…
2020 American Transplant Congress
Trends in Transplant Center Responses to the Minimum Acceptance Criteria Across UNOS Regions, 2007-2019
E. M. Roth¹, Q. Yuan², N. Elias²
¹Harvard Medical School, Boston, MA, ²Transplant Center, Massachusetts General Hospital, Boston, MA
*Purpose: The objective of this study was to examine trends in transplant center willingness to accept organs from Public Health Service increased-risk donors for infectious…
2020 American Transplant Congress
Defining the Psychological Profile of Living Organ Donors Using Personality Assessment Inventory
W. T. Branagan¹, S. Huett¹, M. Grafals², W. E. Jackson³, E. A. Pomfret⁴
¹Division of Psychiatry, University of Colorado, Aurora, CO, ²Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO, ³Division of Gastroenterology and Hepatology, University of Colorado, Aurora, CO, ⁴Division of Transplant Surgery, University of Colorado, Aurora, CO
*Purpose: We aim to assess the psychological profile of living organ donors using normative referenced psychological assessment of personality and pathology.*Methods: Evaluation for living kidney…
2019 American Transplant Congress
Patient Perspectives of Informed Consent for Deceased Donor Organ Intervention Research
E. Gordon¹, B. Knopf¹, A. Mussell², C. Phillips², R. Veatch³, P. Abt², P. Reese²
¹Northwestern University, Chicago, IL, ²University of Pennsylvania, Philadelphia, PA, ³Georgetown University, Washington DC, DC
*Purpose: Interventions on deceased donors or their organs hold promise for increasing the quantity and quality of organs for transplantation by minimizing organ injury and…

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