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American Transplant Congress abstracts

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Articles tagged "Graft acceptance"

  • 2021 American Transplant Congress

    Can Procurement Biopsy Data Tell Us Anything? The Influence of Glomerulosclerosis on Long-term Kidney Graft Survival

    D. Stewart1, L. Kamal2, J. Foutz3, H. McGehee3, P. Saravanane2, S. Yu2, R. Yousfi2, G. Gupta2

    1United Network for Organ Sharing, Richmond, VA, 2Virginia Commonwealth University Health, Richmond, VA, 3Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: Biopsy findings, particularly % glomerulosclerosis, have been shown to have a profound impact on kidney utilization decisions. Most studies of the association between procurement…
  • 2021 American Transplant Congress

    Findings from the Bareto Study: Associations Between Chronic Vascular Changes and 10-year Transplant Graft Outcomes

    L. Kamal1, D. Stewart2, J. Foutz2, H. McGehee2, P. Saravanane1, S. Yu1, R. Yusfi1, G. Gupta1

    1Virginia Commonwealth University, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: As part of a broader study on Biopsy, Anatomy, and Resistance Effects on Transplant Outcomes (BARETO), we aim to characterize the poorly understood relationship…
  • 2021 American Transplant Congress

    Increased T Cell Cross-dressing in Accepted Kidney Allografts

    Q. Yuan1, S. Hong2, E. Szuter2, I. Rosales2, Y. Zhao2, B. Gonzalez-Nolasco2, G. Benichou2, P. Russell2, J. Madsen2, R. Colvin2, A. Alessandrini2

    1Massachusetts General Hospital/Chinese PLA General Hospital, Boston, MA, 2Massachusetts General Hospital, Boston, MA

    *Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) develop tolerance while other combinations do not (e.g. B6 to DBA/2). We…
  • 2021 American Transplant Congress

    Laminin Alpha 4 and Alpha5 Differentially Regulate Lymph Node Tolerogenic Structure

    L. Li1, M. Shirkey1, W. Piao1, Y. Xiong1, V. Saxena1, T. Zhang1, J. Iyyathurai2, R. Lakhan1, R. Abdi3, J. Bromberg1

    1Surgery, UMB, Baltimore, MD, 2CVID, UMB, Baltimore, MD, 3Harvard University, Boston, MD

    *Purpose: Lymph node (LN) stromal laminins α4 (Lama4) and α5 (Lama5) are associated with tolerance and immunity, respectively. We hypothesized that stromal Lama4 and Lama5…
  • 2021 American Transplant Congress

    Review of Unos Report of Organ Offers is Supplemented with Documented Real-time Communication Messages

    E. S. Pahl1, N. Patterson2

    1University of Iowa, Iowa City, IA, 2Iowa Methodist, Des Moines, IA

    *Purpose: Use real time group messaging data among procurement and transplant professionals to supplement the review of UNOS Report of Organ Offers (ROO) for declined…
  • 2021 American Transplant Congress

    First Full Reversal of Diabetes in Non-human Primates (nhp) with Stem Cell Derived Islet-like-clusters (sc-ilcs)

    J. Lei1, S. Collins2, H. Deng1, Z. Yang1, A. Zhang1, C. Peters1, J. Zhang2, K. Boulanger2, M. Yu3, M. Rickels3, C. Liu3, R. Pop2, A. Naji3, D. Melton2, J. Markmann1

    1Surgery, Mass General, Boston, MA, 2Harvard Stem Cell Institute, Harvard University, Boston, MA, 3Surgery, Upenn, Philadelphia, PA

    *Purpose: Deceased donor allo-islet transplants (Tx) have demonstrated the ability of cell-based therapy to fully reverse T1D, however, an inadequate donor supply and frequent need…
  • 2020 American Transplant Congress

    Dual Kidney Transplantation Offers a Safe and Effective Way to Use Kidneys from Deceased Donors Older Than 70 Years

    K. Lee, J. Park, S. Cha, M. Kim

    Samsung Medical Center, Seoul, Korea, Republic of

    *Purpose: Dual kidney transplantation (DKT) offers a way to extend the use of kidneys from expanded criteria donors (ECDs). Here, we compared the outcomes of…
  • 2020 American Transplant Congress

    The Impact of Occult Graft Fibrosis on Clinical Outcomes in Human Liver Transplant Recipients

    H. Hirao1, T. Ito1, B. V. Naini1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Although liver transplantation (LT) has become a standard therapy for end-stage liver disease, early allograft dysfunction (EAD) and graft rejection remain serious unsolved problems.…
  • 2020 American Transplant Congress

    Geographic Discard Disparities of Liver Allografts

    P. I. Kenny Jr1, A. Rana2, J. Vierling2

    1Medical Student, Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, Houston, TX

    *Purpose: The aim of this study is to demonstrate the significant geographic disparity in liver allograft discard.*Methods: Using the OPTN Diseased Donor Network database, we…
  • 2020 American Transplant Congress

    Predicting Kidney Allograft Discard: The Kidney Discard Risk Index

    M. B. Price, M. Joshi, T. Zhang, J. Vierling, T. Galvan, R. Cotton, C. O'Mahony, J. Goss, A. Rana

    Michael E. DeBakey Department of Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX

    *Purpose: The disparity between the supply and demand for kidney allografts is exacerbated by an 18.9% discard rate. It is our aim to determine predictors…
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