ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Glomerular filtration rate (GFR)"

  • 2017 American Transplant Congress

    Even Non-Donor-Specific HLA-Antibodies Are Associated with a Progressive Decline in Kidney Transplant Function.

    T. Mueller, K. Gerritsen, R. van Breemen, B. Ruesi, S. von Moos, P. Cippa.

    University Spital Zuerich, Zuerich, Switzerland

    Donor-specific anti-HLA-Antibodies (DSA) have been shown to be associated with antibody-mediated rejection episodes and a poorer long-term kidney graft function. The impact of anti-HLA-antibodies without…
  • 2017 American Transplant Congress

    Non-Renal Factors Predicting Combined Liver-Kidney Transplantation for Non-Dialysis-Requiring Wait-Listed End Stage Liver Disease Patients: 14 Years of US Experience.

    A. Santos, M. Casey, K. Alquadan, J. Gregg, K. Womer.

    University of Florida, Gainesville, FL

    OBJECTIVE: We aimed to identify the non-renal factors associated with the higher likelihood of combined liver-kidney transplantation (CLKT) vs. liver transplantation alone (LTA) in end…
  • 2017 American Transplant Congress

    Kinetic Estimation of Glomerular Filtration Rate and Urine Creatinine as Predictors of Delayed Graft Function in Kidney Transplantation from Non-Heart Beating Donors.

    M. Calvo, M. Moreno De La Higuera, V. Lopez De La Manzanara, A. Shabaka, M. Poma, I. Perez-Flores, N. Calvo Romero, B. Rodríguez-Cubillo, A. Sanchez-Fructuoso.

    Nephrology, Hospital Clínico San Carlos, Madrid, Spain

    Predicting the occurrence of delayed graft function (DGF) and its duration can facilitate the management of patients after kidney transplantation (KT). Methods: A retrospective study…
  • 2017 American Transplant Congress

    Impact of Pre-Donation eGFR on Long-Term Post-Donation eGFR in Younger Living Kidney Donors.

    D. Vock, H. Ibrahim, A. Matas.

    U of MN, Mpls, MN

    Objective: Most transplant centers require living kidney donors (LKDs) to have a minimum estimated glomerular filtration rate (eGFR) to ensure adequate kidney reserve to withstand…
  • 2017 American Transplant Congress

    The Impact of Hepatitis C Treatment on GFR and Immunosuppression in Renal Transplant Recipients.

    J. Husson, R. Adekunle, B. Ravichandran, P. Mathur, S. Jonchhe, K. Stafford.

    University of Maryland Medical Center, Baltimore, MD

    Background: Renal transplant recipients (RTRs) with HCV are at an increased risk of graft rejection, making treatment of HCV in this population of the utmost…
  • 2017 American Transplant Congress

    Renal Function, Albuminuria, and the Risk of Death and Graft Loss After Kidney Transplantation.

    N. Lam,1 M. Tonelli,2 K. Lentine,3 B. Hemmelgarn,2 F. Ye,1 K. Wen,1 S. Klarenbach.1

    1University of Alberta, Edmonton, Canada; 2University of Calgary, Calgary, Canada; 3Saint Louis University, St. Louis

    In 2012, the KDIGO guidelines updated the classification system for chronic kidney disease to include albuminuria. Whether this classification system prognosticates adverse clinical outcomes among…
  • 2017 American Transplant Congress

    Comparison of Long Term Renal Function Outcomes for Everolimus (EVR) vs. Sirolimus (SIR) vs. Mycophenolate Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant (Ktx).

    H. Tedesco,1 W. Irish,2 K. Dharmesh,3 D. Patel,3 D. Cibrik.4

    1Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2CTI Consulting, Raleigh; 3Novartis Pharmaceuticals Corporation, East Hanover; 4University of Michigan, Ann Arbor

    MPA or mammalian target of rapamycin inhibitors (mTORi [EVR or SIR]) in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine) are used for maintenance…
  • 2017 American Transplant Congress

    A Novel Endpoint for Evaluating the Effect of Everolimus with Reduced Calcineurin Inhibitor on Long-Term Kidney Graft Outcome: The TRANSFORM Study Protocol.

    T. Srinivas,1 C. Legendre,1 F. Oppenheimer,1 H. Tedesco-Silva,1 W.-L. Luo,2 P. Bernhardt,2 C. Sommerer,1 S. Chadban,1 F. Vincenti,1 J. Pascual.1

    1TRANSFORM Study Group, Murray; 2Novartis Pharma AG, Basel, Switzerland

    Purpose: With the advancement of immunosuppressive (IS) agents, while short-term graft outcomes improved significantly, long-term outcomes remain a concern. Both acute rejection (AR) and nephrotoxicity…
  • 2017 American Transplant Congress

    Renal Function, Albuminuria, and the Risk of Cardiovascular Events After Kidney Transplantation.

    N. Lam,1 M. Tonelli,2 K. Lentine,3 B. Hemmelgarn,2 F. Ye,1 A. Bello,1 S. Klarenbach.1

    1University of Alberta, Edmonton, Canada; 2University of Calgary, Calgary, Canada; 3Saint Louis University, St. Louis

    The risk of mortality and graft loss is higher in kidney transplant recipients with reduced estimated glomerular filtration rate (eGFR) and heavier albuminuria. It is…
  • 2016 American Transplant Congress

    Metabolomic Profiling of Individuals with Failing Kidney Allograft.

    R. Bassi,1,2 M. Niewczas,3 L. Biancone,5 S. Bussolino,5 A. Lin,4 A. Chandraker,6 P. Fiorina.1,2

    1Nephrology, Boston Children's Hospital, Boston; 2Transplant Medicine, IRCCS San Raffaele Hospital, Milan, Italy; 3Genetics and Epidemiology, Joslin Diabetes Center, Boston; 4Radiology, Brigham and Women's Hospital, Boston; 5Nephrology and Transplantation, San Giovanni Battista Hospital, Turin, Italy; 6Transplantation Research Center, Brigham and Women's Hospital, Boston.

    Alteration of certain metabolites may play a role in the pathophysiology of renal allograft disease. To explore metabolome abnormalities in individuals with a failing kidney…
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