2018 American Transplant Congress
Long-Term Effects of Ketoconazole in Rapid Tacrolimus Metabolizers Post-Renal Transplantation
Introduction: Genetic polymorphisms in cytochrome P-450 enzymes can cause variations in tacrolimus (tac) metabolism. Ketoconazole (keto), a potent CYP450 and P-glycoprotein inhibitor, can be used…2018 American Transplant Congress
Ischemia Reperfusion Injury & Risk for Antibody Mediated Rejection (ABMR) in HLA Sensitized Patients Treated with C1 Esterase Inhibitor (C1INH)
Introduction: Ischemia reperfusion injury (IRI) contributes to delayed graft function (DGF). IRI/DGF in HLA-sensitized (HS) patients likely activates innate and memory injury pathways that may…2018 American Transplant Congress
Effect and Reasons of Rescue Switch to Belatacept among 73 Calcineurin-Inhibitors Treated Kidney Allograft Recipients – A Three Years Retrospective Cohort, Single Center Study
IntroductionAfter kidney transplantation, long-term immunosuppression with calcineurin inhibitors (CNIs) or mTOR inhibitors (mTORi) leads to adverse effects, such as nephrotoxicity and proteinuria. Currently, available data…2018 American Transplant Congress
Estimated GFR at Donor Screening and Achieved Measured GFR after Living Kidney Donation
Study Purpose: Accurate pre-donation renal function estimation is important to minimize the risk of future severe renal function impairment in living kidney donors. Recent studies…2018 American Transplant Congress
Effects of the Addition of Mycophenolate Mofetil on Renal Outcomes in Liver Transplant Recipients: A Single Center Review
Purpose: To evaluate the use of mycophenolate mofetil (MMF) and its effects on renal outcomes in liver transplant recipientsMethods: Adult liver transplant recipients from September…2018 American Transplant Congress
Probability of Developing Chronic Kidney Disease 1 Year after Living Donor Nephrectomy Correlates with Baseline Kidney Volume and Function
University of Utah, Salt Lake City, UT.
Purpose: Living kidney donor outcomes are tremendously important, especially given expanding donor eligibility. Relative to other predictors, the relationship between remaining kidney volume and post-donation…2018 American Transplant Congress
Comprehensive Assessment of NSAID Use and Potential Nephrotoxicity Risk in Adult Veteran Kidney Transplant Recipients
Ralph H Johnson VAMC, Charleston, SC.
Background: NSAID use is generally recommended to be avoided in kidney transplantation (KTX), but there is paucity in the studies assessing their safety within this…2018 American Transplant Congress
Isolated Pre-Transplant Angiotensin II Type I Receptor Antibodies (AT1R Ab) Are Not Associated with Reduced Graft Function or Hypertension (HTN) in Pediatric Kidney Transplant (Ped KTx) Patients (pts)
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Pre-tx donor-specific antibodies (DSA) raises the risk for antibody-mediated rejection (ABMR) and graft dysfunction. The role of AT1R Ab is unclear. In adults, post-tx…2018 American Transplant Congress
Change in Estimated Glomerular Filtration Rate Pre and Post Development of Donor-Specific Antibodies after Kidney Transplantation
Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens contributes to inferior kidney transplant (KT) outcomes. We assessed the effect of dnDSA on…2017 American Transplant Congress
Renal Function, Albuminuria, and the Risk of Death and Graft Loss After Kidney Transplantation.
In 2012, the KDIGO guidelines updated the classification system for chronic kidney disease to include albuminuria. Whether this classification system prognosticates adverse clinical outcomes among…
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