ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Glomerular filtration rate (GFR)"

  • 2018 American Transplant Congress

    Isolated Pre-Transplant Angiotensin II Type I Receptor Antibodies (AT1R Ab) Are Not Associated with Reduced Graft Function or Hypertension (HTN) in Pediatric Kidney Transplant (Ped KTx) Patients (pts)

    H. Pizzo, J. Choi, M. Haas, X. Zhang, E. Kamil, I. Kim, S. Jordan, D. Puliyanda.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Background: Pre-tx donor-specific antibodies (DSA) raises the risk for antibody-mediated rejection (ABMR) and graft dysfunction. The role of AT1R Ab is unclear. In adults, post-tx…
  • 2018 American Transplant Congress

    Change in Estimated Glomerular Filtration Rate Pre and Post Development of Donor-Specific Antibodies after Kidney Transplantation

    B. Ho,1 S. Montag,1,2 H. Bhagat,3 K. Atiemo,1 A. Daud,1 R. Kang,1 L. Zhao,1,2 J. Schwartz,3 D. Ladner.1

    1Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; 2Dept of Preventive Medicine, Northwestern University, Chicago; 3Astellas Pharma Global Development, Inc., Northbrook.

    Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens contributes to inferior kidney transplant (KT) outcomes. We assessed the effect of dnDSA on…
  • 2018 American Transplant Congress

    Post‐Donation eGFR Levels Predicts New‐Onset Antihypertensive Medication Use after Living Kidney Donation

    K. Lentine,1 D. Segev,2 N. Lam,3 A. Garg,4 A. Naik,5 D. Axelrod,6 H. Xiao,1 M. Henderson,2 A. Massie,2 B. Kasiske,7 G. Hess,8 C. Hsu,9 D. Brennan,2 M. Schnitzler.1

    1Saint Louis Univ, St. Louis; 2Johns Hopkins, Baltimore; 3Univ Alberta, Edmonton, Canada; 4Western Univ, Ontario, Canada; 5Univ Michigan, Ann Arbor; 6Lahey Clinic, Burlington; 7Hennepin County, Minneapolis; 8Symphony Health, Conshohocken; 9UCSF, San Francisco.

    Limited data are available on the outcome implications of renal function after living kidney donation.We constructed a novel database linking SRTR registry identifiers, serum creatinine…
  • 2018 American Transplant Congress

    The Combination of Area under Curve of Estimated Glomerular Filtration Rate for 2 Years and Annual Rate Change of Estimated Glomerular Filtration Rate Predicts Long-Term Graft Survival in Kidney Transplants

    E. Lee,1 J. Jeon,1 S. Kim,1 M. Kim,1 K. Lee,1 H. Jang,1 J. Lee,1 J. Hwang,2 D. Kim,1 Y-.G. Kim,1 H. Oh,1 W. Huh,1 J. Kim.3

    1Department of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Department of Anesthesiology and Pain Medicine, Seoul National University BunDang Hospital, Sungnam, Republic of Korea; 3Department of Surgery, Samsung Medical Center, Seoul, Republic of Korea.

    Improvement of short-term outcomes in kidney transplant (KT) has required clinical trials to evaluate long-term hard outcomes for validation of new therapies. However, because of…
  • 2018 American Transplant Congress

    Two Trajectories of Post-DSA eGFR after Kidney Transplant

    J. Beaumont,1 K. Briley,2 A. Maldonado,3 C. Haisch,2 P. Bolin,2 S. Kendrick,4 H. Jones,4 K. McLawhorn,4 D. Leeser,2 L. Rebellato,2 M. Everly.1

    1Terasaki Research Institute, Los Angeles, CA; 2East Carolina University, Greenville, NC; 3Vidant Medical Center, Greenville, NC; 4Eastern Nephrology Associates, Greenville, NC.

    A clearer understanding of the patterns of glomerular filtration rate (GFR) decline following donor-specific antibody (DSA) development and the factors that might be associated with…
  • 2018 American Transplant Congress

    Impact of Glomerular Filtration Rate Normalization to Body Surface Area on Donor Selection and Outcome in over 4000 Living Kidney Donors

    S. Riad,1 D. Keys,1 D. Vock,1 S. Jackson,1 D. Berglund,1 V. Vakil,1 A. Matas,1 H. Ibrahim.3

    1U of MN, Minneapolis; 2Houston Methodist, Houston.

    Introduction: A donor GFR of ≥ 80 mL/min is a selection criterion. KDIGO recommends that GFR indexed to BSA should be used. Herein, we tested…
  • 2018 American Transplant Congress

    Comparison of Bortezomib in Addition to Rituximab Based Treatment of Acute Antibody Mediated Rejection in Kidney Transplantation

    A. Mattiazzi,1,2 J. Pagan,1,2 A. Arunachalam,1 I. De la Cruz Alcantara,1 J. Revollo,2 A. Centeno,2 A. Valdes,1,2 G. Guerra.1,2

    1Nephrology & Hypertension, University of Miami, Miami, FL; 2Miami Transplant Institute, Jackson Memorial Hospital, Miami, FL.

    Purpose:The optimal treatment strategy of acute antibody mediated rejection (AMR) in renal allograft recipients remains undefined. The aim of our study was to compare the…
  • 2018 American Transplant Congress

    Living-Donor Preemptive Kidney Transplant Timing Calculator: An Online Decision Support Tool

    M. Barah,1 M. Kurt,2 A. Khojandi,1 B. Tanriover.3

    1Industrial and Systems Engineering, Univeristy of Tennessee, Knoxville, TN; 2Economic and Data Sciences, Merck Research Labs, North Wales, PA; 3Division of Nephrology, UT Southwestern Medical Center, Dallas, TX.

    Purpose: Optimal glomerular filtration rate (GFR) and timing for living preemptive kidney transplantation (PKT) is not well studied.Method: We developed an online engine to calculate…
  • 2018 American Transplant Congress

    Impact of Postoperative Serum Chloride Changes on Graft Function and Acute Rejection in Recipients of Living Kidney Transplants

    V. Vakil, D. Keys, M. Junghare, S. Jackson, D. Berglund, A. Matas, S. Riad.

    U of MN, Minneapolis.

    Background: In the non-transplant setting, hyperchloremia has been associated with kidney injury. We sought to study the impact of serum chloride (SCl) on transplant outcomes.Methods:…
  • 2017 American Transplant Congress

    A Single Center Retrospective Review of Pediatric Kidney Transplant Outcomes According to Banff Grade and Cellular Rejection Treatment.

    J. Chen,1 R. Liverman,2 R. Garro,2,3 S. Jernigan,2,3 P. Winterberg.2,3

    1Morgan Stanley Children's Hospital, New York, NY; 2Children's Healthcare of Atlanta, Atlanta, GA; 3Department of Pediatrics, Emory University, Atlanta, GA

    Acute cellular rejection (ACR) remains a major cause of graft dysfunction and loss. There is limited data to provide guidance on optimal treatment strategies stratified…
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