Date: Sunday, June 3, 2018
Session Name: Poster Session B: Kidney Deceased Donor Allocation
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall 4EF
Background: Various kidney donor risk indexes (KDRI) have been developed to predict graft survival with various combinations of donor and recipient characteristics. The aim of this study was to;
Explore relationships between Rao KDRI and recipient estimated glomerular filtration rate (eGFR) at 1yr
Examine the impact of recipient age on eGFR at 1yr
Methods: A retrospective analysis of deceased donor and recipient data from Australian, New Zealand, UK and USA Organ Donor Registries was conducted from 2000-2015. Recipient age was categorised as <30yrs, 30-40yrs, 40-50yrs, 60-70yrs, >70yrs and KDRI was categorised into 4 groups (<1, 1-1.5, 1.5-2, >2). Median eGFR was calculated for the 24 combinations of age and KDRI.
Results: Overall, there were 6,512 Australian, 851 New Zealand, 21,077 UK and 157,664 American recipients (median age 52yrs, [IQR 41-61]). Recipients aged <30yrs receiving a good-quality kidney (KDRI<1.0) achieved a higher median eGFR at 1yr (87.4ml/min/1.73m2) compared with other age groups (median eGFR range: 56.0-63.3ml/min/1.73m2). Recipients aged <30yrs receiving an average-quality kidney (KDRI 1.0-1.5) yielded a better median eGFR of 67.1ml/min/1.73m2 compared with other age groups (median range: 47.8-52.6 ml/min/1.73m2). Recipients aged <30yrs receiving a marginal-quality kidney (KDRI 1.5-2.0) achieved a median eGFR of 53.7ml/min/1.73m2 compared with other age groups (median range: 39.2-44.4ml/min/1.73m2). Recipients aged <30yrs receiving a poor-quality kidney (KDRI>2.0) yielded a better median eGFR of 45.3ml/min/1.73m2 compared with other ages (range: 35.1-36.2 ml/min/1.73m2) (Figure 1).
Conclusions: As KDRI increases, eGFR decreases. Recipients aged <30yrs achieved a substantially higher eGFR at 1yr, independent of donor quality. Only small differences in median eGFR were seen between the other age groups.
CITATION INFORMATION: Chan S., Chatfield M., Baboolal K. Exploring the Impact of Recipient Age with Kidney Donor Risk Index and Estimated Glomerular Filtration Rate at One Year Following Kidney Transplant Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:Chan S, Chatfield M, Baboolal K. Exploring the Impact of Recipient Age with Kidney Donor Risk Index and Estimated Glomerular Filtration Rate at One Year Following Kidney Transplant [abstract]. https://atcmeetingabstracts.com/abstract/exploring-the-impact-of-recipient-age-with-kidney-donor-risk-index-and-estimated-glomerular-filtration-rate-at-one-year-following-kidney-transplant/. Accessed July 8, 2020.
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