ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Glomerular filtration rate (GFR)"

  • 2018 American Transplant Congress

    Ischemia Reperfusion Injury & Risk for Antibody Mediated Rejection (ABMR) in HLA Sensitized Patients Treated with C1 Esterase Inhibitor (C1INH)

    A. Vo,1 O. Aubert,2 J. Choi,1 N. Ammerman,1 H. Edmund,1 A. Peng,1 R. Najjar,1 S. Supreet,1 S. Jordan.1

    1Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; 2Paris Translational Research for Organ Transplantation, Necker Hospital, Paris, France.

    Introduction: Ischemia reperfusion injury (IRI) contributes to delayed graft function (DGF). IRI/DGF in HLA-sensitized (HS) patients likely activates innate and memory injury pathways that may…
  • 2018 American Transplant Congress

    Effect and Reasons of Rescue Switch to Belatacept among 73 Calcineurin-Inhibitors Treated Kidney Allograft Recipients – A Three Years Retrospective Cohort, Single Center Study

    M. Matignon,1 C. Dudreuilh,1 P. Rémy,1 D. Desvaux,2 P. Grimbert.1

    1Nephrology Transplantation, APHP Henri Mondor, Creteil, France; 2Pathology, APHP Henri Mondor, Creteil, France.

    IntroductionAfter kidney transplantation, long-term immunosuppression with calcineurin inhibitors (CNIs) or mTOR inhibitors (mTORi) leads to adverse effects, such as nephrotoxicity and proteinuria. Currently, available data…
  • 2018 American Transplant Congress

    Estimated GFR at Donor Screening and Achieved Measured GFR after Living Kidney Donation

    M. van Londen, J. van der Weijden, S. Bakker, S. Berger, J. Sanders, G. Navis, M. de Borst.

    Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, Netherlands.

    Study Purpose: Accurate pre-donation renal function estimation is important to minimize the risk of future severe renal function impairment in living kidney donors. Recent studies…
  • 2018 American Transplant Congress

    Effects of the Addition of Mycophenolate Mofetil on Renal Outcomes in Liver Transplant Recipients: A Single Center Review

    M. Henry, M. Vacha.

    Nebraska Medicine, Omaha, NE.

    Purpose: To evaluate the use of mycophenolate mofetil (MMF) and its effects on renal outcomes in liver transplant recipientsMethods: Adult liver transplant recipients from September…
  • 2018 American Transplant Congress

    Probability of Developing Chronic Kidney Disease 1 Year after Living Donor Nephrectomy Correlates with Baseline Kidney Volume and Function

    I. Hall, A. Shaaban, S. Beddhu, F. Shihab.

    University of Utah, Salt Lake City, UT.

    Purpose: Living kidney donor outcomes are tremendously important, especially given expanding donor eligibility. Relative to other predictors, the relationship between remaining kidney volume and post-donation…
  • 2018 American Transplant Congress

    Comprehensive Assessment of NSAID Use and Potential Nephrotoxicity Risk in Adult Veteran Kidney Transplant Recipients

    J. Chiasson, C. Fominaya, M. Gebregziabher, D. Taber.

    Ralph H Johnson VAMC, Charleston, SC.

    Background: NSAID use is generally recommended to be avoided in kidney transplantation (KTX), but there is paucity in the studies assessing their safety within this…
  • 2018 American Transplant Congress

    Isolated Pre-Transplant Angiotensin II Type I Receptor Antibodies (AT1R Ab) Are Not Associated with Reduced Graft Function or Hypertension (HTN) in Pediatric Kidney Transplant (Ped KTx) Patients (pts)

    H. Pizzo, J. Choi, M. Haas, X. Zhang, E. Kamil, I. Kim, S. Jordan, D. Puliyanda.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Background: Pre-tx donor-specific antibodies (DSA) raises the risk for antibody-mediated rejection (ABMR) and graft dysfunction. The role of AT1R Ab is unclear. In adults, post-tx…
  • 2018 American Transplant Congress

    Change in Estimated Glomerular Filtration Rate Pre and Post Development of Donor-Specific Antibodies after Kidney Transplantation

    B. Ho,1 S. Montag,1,2 H. Bhagat,3 K. Atiemo,1 A. Daud,1 R. Kang,1 L. Zhao,1,2 J. Schwartz,3 D. Ladner.1

    1Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; 2Dept of Preventive Medicine, Northwestern University, Chicago; 3Astellas Pharma Global Development, Inc., Northbrook.

    Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens contributes to inferior kidney transplant (KT) outcomes. We assessed the effect of dnDSA on…
  • 2018 American Transplant Congress

    Post‐Donation eGFR Levels Predicts New‐Onset Antihypertensive Medication Use after Living Kidney Donation

    K. Lentine,1 D. Segev,2 N. Lam,3 A. Garg,4 A. Naik,5 D. Axelrod,6 H. Xiao,1 M. Henderson,2 A. Massie,2 B. Kasiske,7 G. Hess,8 C. Hsu,9 D. Brennan,2 M. Schnitzler.1

    1Saint Louis Univ, St. Louis; 2Johns Hopkins, Baltimore; 3Univ Alberta, Edmonton, Canada; 4Western Univ, Ontario, Canada; 5Univ Michigan, Ann Arbor; 6Lahey Clinic, Burlington; 7Hennepin County, Minneapolis; 8Symphony Health, Conshohocken; 9UCSF, San Francisco.

    Limited data are available on the outcome implications of renal function after living kidney donation.We constructed a novel database linking SRTR registry identifiers, serum creatinine…
  • 2018 American Transplant Congress

    The Combination of Area under Curve of Estimated Glomerular Filtration Rate for 2 Years and Annual Rate Change of Estimated Glomerular Filtration Rate Predicts Long-Term Graft Survival in Kidney Transplants

    E. Lee,1 J. Jeon,1 S. Kim,1 M. Kim,1 K. Lee,1 H. Jang,1 J. Lee,1 J. Hwang,2 D. Kim,1 Y-.G. Kim,1 H. Oh,1 W. Huh,1 J. Kim.3

    1Department of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Department of Anesthesiology and Pain Medicine, Seoul National University BunDang Hospital, Sungnam, Republic of Korea; 3Department of Surgery, Samsung Medical Center, Seoul, Republic of Korea.

    Improvement of short-term outcomes in kidney transplant (KT) has required clinical trials to evaluate long-term hard outcomes for validation of new therapies. However, because of…
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