ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "FK506"

  • 2016 American Transplant Congress

    Outcomes from De Novo Tacrolimus Weight-Based Dosing Compared to Conservative Dosing in Kidney Transplant Recipients.

    B. Summers,2 K. Szempruch,1 M. Harris,2 A. Quidley,1 C. Haisch,1 A. Maldonado.1

    1Vidant Medical Center/East Carolina University, Greenville, NC; 2Duke University Hospital, Durham, NC.

    Purpose: To compare de novo tacrolimus (TAC) weight based dosing (WDG) and conservative dosing (CDG) on incidence and duration of DGF in adult kidney transplant…
  • 2016 American Transplant Congress

    Comparison of Once-Daily and Twice-Daily Low-Dose Tacrolimus in Living Related Kidney Transplantation – Prospective Trial of Once-Daily vs. Twice-Daily Tac – 5 Years Second Report.

    T. Tsuchiya, H. Ishida, T. Nozaki, H. Shirakawa, T. Shimizu, K. Omoto, M. Okumi, K. Tanabe.

    Department of Urology, Tokyo Women's Medical University, Tokyo, Japan.

    Background; Previously, we reported a comparison of the safety and pharmacokinetics between a prolonged-release formulation of Tacrolimus (Tac-QD) and twice-daily tacrolimus (Tac-BD) in the early…
  • 2016 American Transplant Congress

    Effect of Inflammation on Concentration of Intracellular Tacrolimus.

    E. Bae,1 S. Yang,2 S. Han,1 J.-Y. Park,1 H. Lee,1 Y. Kim.1

    1Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 2Kidney Research Institute, Seoul National University, Seoul, Republic of Korea.

    Background: The use of calcineurin inhibitors improved the outcome for transplant recipients. However, acute rejection (AR) and infection remained still an unsolved problem. We evaluated…
  • 2016 American Transplant Congress

    A Novel Inflammation-Targeting Tacrolimus Hydrogel for Liver Transplantation.

    J. Jia,1 J. Li,12 Y. Zhou,1 L. Jiang,1 J. Zhang,1 H. Lu,1 H. Xie,1 L. Zhou,1 P. Kumur,3 S. Zheng.12

    1Key Laboratory of Combined Multiorgan Transplantation, Ministry of Public Health, Hangzhou, China; 2Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; 3Division of Biomedical Engineering and Department of Medicine, Brigham and Women's Hospital, Boston.

    Background:Immunosuppressant have played a critical role for improving graft survival after liver transplantation (LT). While long-term systemic use of immunosuppressant such as tacrolimus (FK506) is…
  • 2016 American Transplant Congress

    Tacrolimus Levels in Patients Treated with Direct Acting Antivirals Post-Transplant.

    J. Wiegel, T. Egbuka.

    Pharmacy, Oregon Health & Science University, Portland, OR.

    Purpose: To determine if treatment of recurrent hepatitis C virus (HCV) post-liver transplant with the direct-acting antivirals (DAAs) sofosbuvir, simeprevir, and ledipasvir (in combination and/or…
  • 2016 American Transplant Congress

    How Tacrolimus Variability Affects Donor Specific Antibodies, Rejection and Outcome After Kidney Transplantation.

    S. Papachristos, A. John Velvet, A. Summers, A. Tavakoli, R. Dhanda, R. Pararajasingam, B. Forgacs.

    Manchester Transplantation Unit, Manchester Royal Infirmary Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.

    Purpose:To investigate the effect of tacrolimus(tac) variability on the development of Donor Specific Antibodies(DSA),rejection and outcome in relation to Age, Gender, Ethnicity and Body Mass…
  • 2016 American Transplant Congress

    Prospective Randomized Controlled Study Evaluating the Impact of an Electronic Feedback System on Medication Adherence in Solid Organ Transplantation.

    M. Lockwood, L. Potter, B. Kane, L. Lourenco, A. Bozdin, J. Millis.

    University of Chicago Transplant Center, University of Chicago, Chicago.

    Purpose: To evaluate the impact of and electronic feedback system (EFS), SIMpill Medication Adherence System®, on medication adherence in patients who have received a solid…
  • 2016 American Transplant Congress

    Advantages of Computerized Dosing Strategy in Tacrolimus Treatment of Renal Transplant Patients.

    S.-Y. Kim,1 S. Cho,1 M.-J. Cho,1 C. Lee,1 A. Han,1 C. Choi,1 S. Ahn,1 S.-I. Min,1 S.-K. Min,1 M. Park,2 I. Jung,3 S. Kim,4 J. Ha.1,2

    1Department of Surgery, Seoul National University Hospital, Seoul, Korea; 2Korea Organ Donation Agency, Seoul, Korea; 3Department of surgery, Seoul Metropolitan Government - Seoul National University Boramae Medical Center, Seoul, Korea; 4Department of Surgery, Myoungji Hospital, Goyang-si, Korea.

    Purpose: Tacrolimus (Tac) is widely used in immunosuppression for kidney transplant (KT) patients. Despite this, it is still difficult for expert physicians to achieve and…
  • 2016 American Transplant Congress

    Influence of the Tacrolimus Metabolism Rate on BKV Infection After Kidney Transplantation.

    G. Thölking,1 C. Schmidt,1 K. Schuette-Nuetgen,1 D. Pabst,1 R. Koch,2 H. Wolters,3 S. Reuter,1 B. Suwelack.1

    1Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Münster, Münster, Germany; 2Institute of Biometrics and Clinical Research, University of Münster, Münster, Germany; 3Department of General Surgery, University Hospital of Münster, Münster, Germany.

    Introduction: BK virus (BKV) infection is a serious complication following renal transplantation (RTx). The minimization of risk factors that predict BKV infection might help to…
  • 2016 American Transplant Congress

    Comparison of Transplant Outcomes for Low-Dose and Standard-Dose Tacrolimus in Kidney Transplant Recipients.

    J.-H. Cho, K. Kim, M. Kim, W. Do, Y. Yang, T. Yim, I. Hwang, J.-H. Lee, E. Kwon, H.-Y. Jung, J.-Y. Choi, S.-H. Park, Y.-L. Kim, C.-D. Kim.

    Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

    Objectives: There are few studies that compare the effect of different dose of tacrolimus after kidney transplantation. We investigated transplant outcome of low-dose and standard-dose…
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