Date: Tuesday, June 14, 2016
Session Name: Concurrent Session: Psychosocial and Treatment Adherence
Session Time: 4:30pm-6:00pm
Presentation Time: 4:54pm-5:06pm
Location: Room 206
Purpose: To evaluate the impact of and electronic feedback system (EFS), SIMpill Medication Adherence System®, on medication adherence in patients who have received a solid organ transplant.
Methods: A total of 89 solid organ transplant recipients were randomized to 1 of 4 groups; 2 intervention groups (I1 and I2) & 2 control groups (C1 and C2). Subjects in I1 or I2 received EFS, a medication-dispensing device that communicates timing of openings or doses taken to a secure server. If a medication dose is missed a text reminder message is sent to the subject (I1). In addition to patient reminders, providers were notified if consecutive doses were missed over a 72 hour period (I2), enabling intervention. C1 received an EFS device but feedback was not provided to the patient or provider. C2 did not receive an EFS device.
Results: A total of 39 subjects from two subgroups, I1 (N=20) and C1 (N=19), were selected for analysis with Mann-Whitney U tests. A majority of patients used the device for greater than 6 months. Median comparison of total doses taken, days with correct dosing, and doses taken within 2 hours of target time were significantly greater in I2 compared to C1.
|Adherence Parameter||Intervention Group 2 (N=20)||Control Group 1 (N=19)||p value|
| Total Doses Taken|
| Days with Correct Dosing|
| Doses Taken within Two Hours of Target Time|
Conclusion: The use of an EFS, such as the SIMpill Medication Adherence System®, may improve adherence in solid organ transplant recipients, may allow for identification of medication non-adherence, and may facilitate provider intervention for non-adherence.
CITATION INFORMATION: Lockwood M, Potter L, Kane B, Lourenco L, Bozdin A, Millis J. Prospective Randomized Controlled Study Evaluating the Impact of an Electronic Feedback System on Medication Adherence in Solid Organ Transplantation. Am J Transplant. 2016;16 (suppl 3).
To cite this abstract in AMA style:Lockwood M, Potter L, Kane B, Lourenco L, Bozdin A, Millis J. Prospective Randomized Controlled Study Evaluating the Impact of an Electronic Feedback System on Medication Adherence in Solid Organ Transplantation. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/prospective-randomized-controlled-study-evaluating-the-impact-of-an-electronic-feedback-system-on-medication-adherence-in-solid-organ-transplantation/. Accessed June 3, 2020.
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