2022 American Transplant Congress
Poor Tolerability of CFTR Modulator Therapy in Lung Transplant Recipients
*Purpose: Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) is a highly effective therapy for cystic fibrosis (CF) with potential benefits in lung transplant recipients (LTRs) for extrapulmonary CF manifestations, however…2022 American Transplant Congress
Evaluation of Conversion from Immediate Release (IR) Tacrolimus to LCP-Tacrolimus (Envarsus XR®, LCP) in Heart Transplant Recipients
1University of Illinois at Chicago, Chicago, IL, 2Loyola University Medical Center, Maywood, IL
*Purpose: The purpose of this study was to assess outcomes in heart transplant recipients who were converted from IR tacrolimus to LCPT. Limited data exists…2022 American Transplant Congress
Noroviral Diarrhea in Solid Organ Transplant Recipients: Characteristics, Interventions and Outcomes
University of Minnesota, Minneapolis, MN
*Purpose: Norovirus may result in significant morbidity in solid organ transplant (SOT) recipients. There is limited evidence for therapeutics beyond supportive care for the management…2022 American Transplant Congress
Enhanced Delivery of Nanomedicine to Human Kidney During Ex Vivo Perfusion
*Purpose: An efficient delivery of therapeutic agents to graft endothelial cells (ECs) prior to transplantation could render organs more resistant to injury, improving clinical outcomes…2022 American Transplant Congress
Complement 5 Regulation Ameliorates Antibody-Mediated Rejection After Liver Transplantation in Rats
*Purpose: Antibody-mediated rejection (AMR) is a refractory rejection after donor-specific antibody (DSA)-positive or blood-type incompatible organ transplantation. Since AMR significantly deteriorates transplant outcomes, there is…2022 American Transplant Congress
Benefits of Inactivated Vaccine and Viral Vector Vaccine Immunization on Covid-19 Infection in Kidney Transplant Recipients
*Purpose: Most developing countries do not have access to high-efficiency mRNA vaccine. In Thailand, the first and most available vaccines were inactivated, and later on,…2022 American Transplant Congress
External Validation of the Abbreviated Ibox Scoring System at One-Year Post Kidney Transplant as a Surrogate Endpoint for Death-Censored Graft Survival
*Purpose: The Transplant Therapeutics Consortium seeks to translate the iBox from Loupy et al., 2019 into a surrogate endpoint for five-year death-censored graft survival after…2022 American Transplant Congress
Safety and Efficacy at 4 Years in Post-Liver Transplant Patients with Chronic Kidney Disease Receiving Tenofovir Alafenamide (TAF) for HBV Prophylaxis
*Purpose: Recommended antiviral prophylaxis to prevent recurrent HBV infection after liver transplantation includes tenofovir disoproxil fumarate (TDF). However, given risks of bone/renal toxicity associated with…2022 American Transplant Congress
Safety and Efficacy of Sodium Glucose Cotransporter-2 Inhibitors in Solid Organ Transplant Recipients
University Health, San Antonio, TX
*Purpose: To determine the safety and efficacy of sodium glucose cotransporter-2 inhibitors (SGLT2i) in solid organ transplant.*Methods: This is a retrospective review of adult kidney,…2022 American Transplant Congress
Mhealth Coaching Improves Patient Activation and Nutritional Behaviors in Diverse Renal Transplant Recipients
*Purpose: Kidney transplant recipients who are not actively engaged in their care and lack self-management skills have poor transplant outcomes. These suboptimal outcomes are disproportionately…
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