ATC Abstracts

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Articles tagged "Cytomeglovirus"

  • 2016 American Transplant Congress

    Development of a Sequencing-Based Cytomegalovirus UL55 Glycoprotein B (gB) Genotyping Assay.

    S. Cowden, K. Grantham, I. Caton, J. Hester, M. Altrich, S. Kleiboeker.

    Viracor-IBT Laboratories, Lee's Summit, MO.

    Background: Human cytomegalovirus (hCMV) is an important agent of serious viral infection in the solid organ transplant and allogeneic hematopoietic stem cell transplant populations. Severe…
  • 2016 American Transplant Congress

    Cytometric Deep Profiling of the CD8+ T-Cell Compartment in Transplant Patients with CMV Viremia.

    V. Ferreira, D. Kumar, S. Husain, M. Bhat, P. Ashton, A. Humar.

    UHN, Toronto, Canada.

    Background: Cytomegalovirus (CMV) infection is a common opportunistic viral infection in transplant patients. Patterns of viremia and relapse are influenced by the host immune response,…
  • 2015 American Transplant Congress

    Invasive CMV-Infection of the Duodenal Cuff – An Underestimated Entity of CMV Infection and Its Potential Impact On Outcome After Pancreas Transplantation

    A. Biglarnia,1 B. von Zur-Mühlen,1 S. Yamamoto,1 D. Berglund,1 M. Wagner,2 A. Sedigh,1 G. Tufveson,1 E. Larsson,3 F. Sund.2

    1Transplantation, Surgical Sciences, Uppsala, Sweden; 2Medical Scinces, Upsala, Sweden; 3Genetics and Pathology, Uppsala, Sweden.

    IntroductionWe present data on the incidence of focal invasive CMV-infection of the duodenal cuff and its potential impact on clinical outcome after pancreas transplantation (PT).Material…
  • 2015 American Transplant Congress

    The Impact of Administrating Everolimus Before Cytomegalovirus Infection to Prevent CMV Recurrence in Heart Transplant Recipients

    M. Ishida, K. Toda, T. Nakamura, S. Miyagawa, Y. Yoshikawa, S. Fukushima, S. Saito, D. Yoshioka, K. Kubota, T. Ueno, T. Kuratani, Y. Sawa.

    Cardiovascular Surgery, Osaka University, Suita, Osaka, Japan.

    Purpose – Cytomegalovirus (CMV) infection is a major complication in heart transplant recipients. Recent trials indicate that the use of the mammalian target of rapamycin…
  • 2015 American Transplant Congress

    Reduced Incidence of Cytomegalovirus Infection in Kidney Transplant Recipients Receiving Everolimus

    H. Tedesco-Silva,1 C. Felipe,1 A. Ferreira,1 M. Cristelli,1 T. Sandes- Freitas,1 N. Oliveira,1 W. Aguiar,2 G. Bassos,1 M. Franco,3 M. Gerbase- Lima,4 E. Campos,4 J. Medina-Pestana.1

    1Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2Urology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 3Pathology, UNIFESP, Sao Paulo, Brazil; 4Immunogenetic, AFIP, Sao Paulo, Brazil.

    BACKGROUND: CMV infection is associated with inferior long-term kidney transplant outcomes. This study compared the incidence of CMV infection/disease in de novo kidney transplant recipients…
  • 2015 American Transplant Congress

    Preventing Cytomegalovirus Infection in Intermediate-High Risk Liver Transplant Recipients: Acyclovir Vs Valganciclovir

    S. Dulanya, A. Anamisis, D. Tsapepas.

    Department of Pharmacy, New York Presbyterian Hospital, New York City, NY.

    Cytomegalovirus (CMV) is an opportunistic infection responsible for profound morbidity and mortality among solid organ transplant recipients. A donor and recipient's CMV IgG serostatus influences…
  • 2015 American Transplant Congress

    Everolimus Versus Mycophenolate for Recipients of Kidney Transplants from Expanded Criteria Donors (ECD) Receiving Anti-Thymocyte Globulin and Tacrolimus

    H. Tedesco-Silva,1 C. Felipe,1 A. Ferreira,1 M. Cristelli,1 A. Bessa,1 P. Ueno,1 T. Sandes- Freitas,1 G. Bassos,1 W. Aguiar,2 H. Proença,3 J. Medina-Pestana.1

    1Nephrology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2Urology, Hospital do Rim UNIFESP, Sao Paulo, Brazil; 3Pathology, UNIFESP, Sao Paulo, Brazil.

    Introduction: Recipients of kidneys recovered from expanded criteria donors are at higher risk to develop delayed graft function (DGF) and acute rejection (AR), leading to…
  • 2015 American Transplant Congress

    CMV-Specific CD154+T-Cells and CMV Disease Status After Liver Or Intestine Transplantation (LTx, ITx)

    C. Ashokkumar,1 M. Ningappa,1 G. Mazariegos,1 K. Soltys,1 G. Bond,1 C. Trautz,1 M. Green,2 M. Michaels,2 R. Sindhi.1

    1Transplant Surgery, University of Pittsburgh, Pittsburgh, PA; 2Infectious Diseases, University of Pittsburgh, Pittsburgh, PA.

    Background: Preliminary data suggest that measuring host cellular immunity using CMV-specific IFNg+T-cells can potentially enhance decision making about discontinuation of antiviral therapy and secondary prophylaxis…
  • 2015 American Transplant Congress

    Myeloid Cells as a Key Mediator for Impairment of Transplant Tolerance by CMV Infection

    L. Zhang,1 X. Zhang,2 H. Kang,1 X.-F. Liu,2 S. Yan,2 J.-J. Wang,2 M. Abecassis,2 Z. Zhang,2 M. Hummel,2 X. Luo.1,2

    1Medicine, Northwestern University Feinberg school of Medicine, Chicago, IL; 2Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Cytomegalovirus (CMV) is a ubiquitous virus that presents a significant risk for reactivation or de novo infection in transplant recipients. Clinical transplant tolerance has recently…
  • 2015 American Transplant Congress

    A Primary Cytomegalovirus Infection Post-Transplantation Has a Significant Impact on Circulating T Cells and Renal Allograft Function

    R. Meijers,1 N. Litjes,1 A. Langerak,2 C. Baan,1 M. Betjes.1

    1Internal Medicine section Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands; 2Immunology, Erasmus MC, Rotterdam, Netherlands.

    Study's purpose: Cytomegalovirus (CMV)-infection may profoundly affect the peripheral T-cell compartment and is associated with T-cell ageing and generation of cytotoxic CD4+CD28null T cells. We…
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