ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Cytomeglovirus"

  • 2020 American Transplant Congress

    Evaluation of the Safety and Efficacy of Valganciclovir to Prevent Cytomegalovirus Infection in Pediatric Solid Organ Transplant Recipients Utilizing Two Dosing Regimens

    K. Le, A. Patel, N. M. Jasiak-Panek

    Pharmacy, Ann and Robert H. Lurie Children's Hospital, Chicago, IL

    *Purpose: Valganciclovir (VGCV) is FDA-approved for CMV prophylaxis in children aged one month to sixteen years old using the Pescovitz algorithm (7 x body surface…
  • 2020 American Transplant Congress

    The Value of Pharmacist-Driven Valganciclovir Dosing in Kidney Transplant Recipients in Reducing CMV Infection: A Single Center Experience

    K. D. Belfield1, C. E. Costello2, M. Malinis3

    1Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, 2University of Connecticut School of Pharmacy, Storrs, CT, 3Section of Infectious Diseases,, Yale School of Medicine, New Haven, CT

    *Purpose: Cytomegalovirus (CMV) is a common viral infection after kidney transplant (KT) despite prophylaxis with valganciclovir (VGCV). VGCV is renally dosed and can be a…
  • 2020 American Transplant Congress

    CMV, EBV and BKV Viremia Rate Varied Depending on the Timing of Conversion to Belatacept (BLT)- from Calcineurin Inhibitor (CNI)-Based Immunosuppression and HLA-Sensitization (HS) Status in Kidney Transplant Patients (KTx Pts)

    B. Shin, N. Ammerman, A. Vo, S. C. Jordan, M. Toyoda, S. Sethi

    Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Viral infections (VI) represent significant morbidity and mortality factors for KTx Pts. We previously showed more VI in BLT-treated Pts compared with CNI Pts…
  • 2020 American Transplant Congress

    Reduced Dose Valganciclovir is Effective for CMV Prevention without Excess Breakthrough or Resistance in Kidney Transplantation

    M. Luu1, P. Klem1, B. Crowther1, M. Abidi2, M. Miller1, K. Schoeppler1, S. Davis2

    1Pharmacy, University of Colorado Hospital, Aurora, CO, 2Medicine, University of Colorado, Aurora, CO

    *Purpose: Reduced dose valganciclovir (VGC) (450 mg daily) may be a useful alternative to full dose VGC for cytomegalovirus (CMV) prophylaxis due to drug cost…
  • 2020 American Transplant Congress

    Efficacy Of CMV Prophylaxis In Liver Transplant Recipients

    S. LeCorchick, T. Tinkham, N. Oliver, L. Lindberg, L. Dong, J. Krong, R. Gilroy

    Intermountain Medical Center, Murray, UT

    *Purpose: Human cytomegalovirus (CMV) is a ubiquitous beta herpesvirus present in the human population at rates between 30% and 90%. It can be transmitted via…
  • 2020 American Transplant Congress

    Conversion to Belatacept (BLT)- from Calcineurin Inhibitor (CNI)-Based Immunosuppression During the First Year Post-Transplant (<1yr Tx) Increases Risk for CMV Infection Through Inhibition of Anti-CMV Humoral Immunity

    B. Shin, N. Ammerman, S. Sethi, A. Vo, S. C. Jordan, M. Toyoda

    Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: We have shown a higer CMV infection rate in kidney Tx patients (KTx Pts) who were converted to BLT 1yr post-Tx. Viral infections are…
  • 2020 American Transplant Congress

    Use of Letermovir for Cytomegalovirus Management in Thoracic Organ Transplantation

    J. L. Saullo, A. Ferrari, E. M. Eichenberger, J. M. Steinbrink, A. W. Baker, M. Bacchus, E. K. Maziarz, S. Kakoullis, L. Zaffiri, H. Berry, J. M. Reynolds, C. R. Wolfe

    Duke University Medical Center, Durham, NC

    *Purpose: Cytomegalovirus (CMV) commonly affects thoracic solid organ transplant (SOT) recipients, and standard antiviral therapies are limited by myelosuppression, renal dysfunction, and emergence of resistance.…
  • 2020 American Transplant Congress

    A Comprehensive Evaluation of Risk Factors for Pneumocystis Jiroveci Pneumonia in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis

    N. Permpalung1, V. Kittipibul2, P. Mekraksakit3, P. Rattanawong4, S. Nematollahi1, S. Mehta-Steinke1

    1Johns Hopkins University School of Medicine, Baltimore, MD, 2University of Miami/Jackson Memorial Hospital, Miami, FL, 3Texas Tech University Health Sciences, Lubbock, TX, 4Mayo Clinic, Phoenix, AZ

    *Purpose: Pneumocytis jiroveci pneumonia (PJP) is an important opportunistic fungal infection in solid organ transplant (SOT) recipients that carries a significant morbidity and mortality. Several…
  • 2020 American Transplant Congress

    Single Center Experience of Valganciclovir and Adjunctive CMV IVIG for the Treatment of CMV Infection in Lung Transplant Recipients

    A. A. Fernandez1, N. Sinha2, M. Loebe2, J. Glaze2, S. Manickavel2, M. Fernandez2, T. Pastrana2, J. Simkins3, J. Camargo3, M. I. Morris3, L. Abbo3, Y. Natori3

    1Infectious Disease, University of Miami Jackson Memorial Hospital, Miami, FL, 2University of Miami Jackson Memorial Hospital, Miami, FL, 3Transplant Infectious Disease, University of Miami Jackson Memorial Hospital, Miami, FL

    *Purpose: Cytomegalovirus(CMV) infection happens commonly and causes significant morbidity in lung transplant (LTx) recipients. The use of CMV hyperimmune globulin (CMVIg) as an adjunctive treatment…
  • 2020 American Transplant Congress

    Letermovir Treatment for Established Cytomegalovirus Infection in Transplant Recipients

    K. Linder1, C. Kovacs2, K. Mullane3, C. Wolfe4, N. Clark5, C. Butkus Small6, R. La Hoz7, J. Smith8, C. Kotton9, A. Limaye10, M. Malinis11, M. Hakki12, A. Mishkin13, A. Gonzalez14, D. Kaul1

    1U Michigan, Ann Arbor, MI, 2Cleveland Clinic, Cleveland, OH, 3U Chicago, Chicago, IL, 4Duke, Durham, NC, 5Loyola, Chicago, IL, 6Cornell, NYC, NY, 7UTSW, Dallas, TX, 8U Wisconsin, Madison, WI, 9Mass General, Boston, MA, 10U Washington, Seattle, WA, 11Yale, New Haven, CT, 12OHSU, Portland, OR, 13Temple, Philadelphia, PA, 14West Coast ID, Safety Harbor, FL

    *Purpose: The purpose of the study was to describe the patterns of use and clinical/virologic outcomes of letermovir treatment for established CMV infection in transplant…
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