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Articles tagged "Cytomeglovirus"

  • 2020 American Transplant Congress

    Cmv Infection Sensitizes Transplant Recipients by Promoting Alloreactive T Cell Response

    S. Yu, A. Dangi, X. Luo

    Nephrology/Medicine, Duke University, Durham, NC

    *Purpose: Cytomegalovirus (CMV) infection has been associated with allograft rejection in immunosuppressed transplant recipients. We have previously shown that acute CMV infection impairs the induction…
  • 2020 American Transplant Congress

    Efficacy and Safety of Cytomegalovirus Antiviral Preventive Strategies in Kidney Transplant: A Systematic Literature Review

    A. Raval1, K. Kistler2, Y. Tang1, Y. Murata1, D. Snydman3

    1Merck & Co., Inc., Kenilworth, NJ, 2Evidera, Inc., Waltham, MA, 3Tufts Medical Center, Boston, MA

    *Purpose: Cytomegalovirus (CMV) is associated with significant mortality and morbidity in kidney transplant recipients (KTRs). Various CMV anti-viral (AV) preventive strategies have been utilized in…
  • 2020 American Transplant Congress

    Next-Generation Sequencing to Assess Cytomegalovirus Viral Populations During the Course of CMV Infection

    G. Elhelou1, R. Razonable2

    1Medicine, Division of Infectious Diseases and Global Medicine, University of Florida, Gainesville, FL, 2Medicine, Division of Infectious Disease, Mayo Clinic, Rochester, MN

    *Purpose: Resistant Cytomegalovirus (CMV) infection has emerged to cause significant impact on morbidity and mortality after solid organ transplantation (SOT). There is limited data on…
  • 2020 American Transplant Congress

    Lymphycyte Subset Test as a Determinant of Cytomegalovirus Prophylaxis in Renal Transplant Recipients

    M. Kim, Y. Park, S. Mok, K. Jun, S. Kim, J. Kim, S. Yun, I. Moon, S. Park

    Surgery, The Catholic University of Korea, Seoul, Korea, Republic of

    *Purpose: Cytomegalovirus (CMV) infection is an important complication after kidney transplantation (KT). Anti-thymocyte globulin (ATG) increases a risk of CMV infection and the American society…
  • 2020 American Transplant Congress

    Utility of Bimonthly Viral Monitoring for Late-Onset Cytomegalovirus Infections in Kidney Transplant Recipients

    I. Melgarejo1, D. Jorgensen2, S. Hariharan2, C. Puttarajappa2

    1Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, 2Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Kidney transplant recipients with high-risk cytomegalovirus (CMV) serostatus are at risk for late onset CMV after cessation of antiviral prophylaxis.1-2 Evidence for post-prophylactic viral…
  • 2020 American Transplant Congress

    Absolute Lymphocyte Count: Is There a “Safety Corridor?”

    G. Elhelou1, B. Lahr2, R. Razonable3

    1Medicine, Division of Infectious Diseases and Global Medicine, University of Florida, Gainesville, FL, 2Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 3Medicine, Division of Infectious Disease, Mayo Clinic, Rochester, MN

    *Purpose: Iatrogenic suppression of T cells is intended to prevent rejection after solid organ transplantation (SOT). This is complicated by opportunistic infections, most notably cytomegalovirus…
  • 2020 American Transplant Congress

    Effectiveness of Preemptive Therapy in the Prevention of Cytomegalovirus (CMV) Disease in High-Risk (Donor Seropositive/Recipient Seronegative) Liver Transplant Recipients

    J. A. Morillas, K. Brizendine

    Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Guidelines recommend preemptive therapy (PET) as one strategy for prevention of CMV disease in high risk liver transplant recipients (LTR). However, questions have been…
  • 2020 American Transplant Congress

    Epidemiology of Cytomegalovirus (CMV) in Pediatric Solid Organ Transplant Recipients (SOTR) at Texas Children’s Hospital (TCH)

    K. Valencia, K. Hosek, E. Moulton, F. Munoz, G. Demmler-Harrison, C. Bocchini

    Baylor College of Medicine, Houston, TX

    *Purpose: Despite widespread use of prevention strategies, CMV remains a common opportunistic infection in SOTR. Contemporary data regarding CMV in pediatric SOTR is limited. We…
  • 2019 American Transplant Congress

    Long-Term Efficacy and Safety of Everolimus Based Immunosuppression on De Novo Kidney Transplantation with 10 Years Follow-Up

    Y. Watarai1, S. Narumi1, T. Tomosugi1, K. Futamura2, M. Okada1, M. Tsujita2, T. Hiramitsu1, T. Kobayashi3, N. Goto2

    1Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan, 2Transplant Nephrology, Nagoya Daini Red Cross Hospital, Nagoya, Japan, 3Kidney Transplantation, Aichi Medical University, Nagoya, Japan

    *Purpose: Long-term efficacy and safety of everolimus (EVR) based immunosuppression for de novo kidney transplant recipient who were involved in A1202 study from our institute…
  • 2019 American Transplant Congress

    Real World Data Support International Consenus Guidelines on Management of CMV after Kidney Transplantation

    A. Asberg, G. B. Kro, A. V. Reisæter, A. Hartmann, K. Midtvedt

    Oslo University Hospital - Rikshospitalet, Oslo, Norway

    *Purpose: Cytomegalovirus (CMV) naïve kidney transplant recipients (R-) transplanted with an organ from a CMV positive donor (D+) are at high risk for CMV disease.…
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