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Articles tagged "Cytomeglovirus"

  • 2020 American Transplant Congress

    Safety and Efficacy of Prophylactic Valganciclovir Dosing after Solid Organ Transplant

    K. Gandhi, D. Masic, M. Santarossa, F. Albarillo, N. Clark, G. Reid

    Loyola University Medical Center, Maywood, IL

    *Purpose: At centers where antiviral prophylaxis is used after solid organ transplant, valganciclovir is administered for the prevention of cytomegalovirus (CMV). At Loyola University Medical…
  • 2020 American Transplant Congress

    Impact and Outcomes of Primary Cytomegalovirus Infection in Seronegative Abdominal Solid Organ Transplant Recipients of Cytomegalovirus Unexposed Donors (D-/R-)

    M. Jorgenson1, M. Hillis1, N. Friedlander1, A. Gracon2, D. Yang2, G. Leverson2, J. Smith2, R. Redfield2

    1UWHC, Madison, WI, 2UWMF, Madison, WI

    *Purpose: Primary cytomegalovirus infection (CMV) in high risk (D+/R-) abdominal solid organ transplant recipients (aSOTRs) is well described, however there is a paucity of literature…
  • 2020 American Transplant Congress

    Crispr-Based Diagnostics for Rejection and Opportunistic Infection Detection in Kidney Transplantation

    I. T. Lape1, M. M. Kaminski2, E. Akalin3, J. Collins2, L. W. Riella1

    1Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA, 2Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 3Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY

    *Purpose: There is an unmet need in transplantation to identify allograft injury non-invasively. More than 50% of patients with kidney transplants lose their grafts within…
  • 2020 American Transplant Congress

    Efficacy and Safety According to Dose of Valganciclovir for Cytomegalovirus Prophylaxis in Transplantation Network Meta Analysis

    S. Hwang, W. Park, K. Kim, J. Song, S. Lee

    Inha University, Incheon, Korea, Republic of

    *Purpose: Valgancivlovir is importantly used to prevent post-transplant CMV infection among kidney transplantation patients. However, the dose of such drug being used still remains controversial…
  • 2020 American Transplant Congress

    Multicenter Evaluation of Cytomegalovirus Infection Following Intestinal and Multivisceral Transplantation

    M. Segovia1, Y. Patel1, S. Nagai2, D. Sudan1, S. Jafri2

    1Duke University Hospital, Chapel Hill, NC, 2Henry Ford Hospital, Detroit, MI

    *Purpose: Evaluate factors related to incidence and outcomes of cytomegalovirus (CMV) infection after isolated intestinal transplantation (IT) and multivisceral transplantation (MVT).*Methods: Retrospective evaluation of 32…
  • 2020 American Transplant Congress

    Conversion to Sirolimus to Prevent Recurrent Cytomegalovirus Infection/Disease: A Prospective and Randomized Trial

    L. Almeida Viana, M. Pontello Cristelli, G. Basso, D. Wagner Castro Lima Santos, M. Taver Costa Dantas, Y. Cardoso Dreige, L. Damasceno, M. Rika Nakamura, H. Tedesco-Silva, J. Medina-Pestana

    Hospital do Rim - UNIFESP, São Paulo, Brazil

    *Purpose: Recurrent cytomegalovirus (CMV) infection occurs in 30-35% of kidney transplant recipients after completion of treatment and/or preemptive therapy. There is no consensus on the…
  • 2020 American Transplant Congress

    Influence of HLA Compatibility on Cytomegalovirus Infection Post-Kidney Transplantation

    N. Fujiyama1, M. Saito2, R. Yamamoto2, K. Numakura2, T. Inoue2, R. Sagehashi2, K. Hosomichi3, A. Miura1, T. Habuchi2, S. Satoh1

    1Center for Kidney Disease and Transplantation, Akita University Hospital, Akita, Japan, 2Department of Urology, Akita University Graduate School of Medicine, Akita, Japan, 3Department of Bioinformatics and Genomics, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan

    *Purpose: Cytomegalovirus (CMV) infection after kidney transplantation is associated with a high morbidity and higher risk of graft loss. A latent Human CMV infection can…
  • 2020 American Transplant Congress

    Identification of Cell Types That Harbor Cytomegalovirus DNA in Acutely and Latently Infected Mice Spleen

    A. S. Maganti1, X. Liu2, M. Abecassis2

    1Illinois Math and Science Academy, Aurora, IL, 2Comprehensive Transplant Center, Northwestern University, Chicago, IL

    *Purpose: Cytomegalovirus (CMV) is a ubiquitous β‐herpesvirus that infects majority of humans. Primary CMV infection may be asymptomatic or manifests as a self‐limited febrile illness…
  • 2019 American Transplant Congress

    Impact of Cytomegalovirus on the Immune System of Healthy Humans

    W. Zhang, J. Robertson, G. Karadkhele, B. Johnson, C. Larsen

    Emory Transplant Center, Emory University, Atlanta, GA

    *Purpose: CMV is a frequent pathogen after transplantation. 2/3 of recipients harbor latent CMV and are at moderate risk. CMV- recipients divide into high or…
  • 2019 American Transplant Congress

    Letermovir for CMV Treatment in Solid Organ Transplant

    O. Witkowsky, M. Chunduru, A. Chung, A. Diez

    The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: Letermovir (LET), a novel anti-CMV agent, was recently approved for CMV prophylaxis in stem cell transplant recipients and is currently under investigation as a…
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