2020 American Transplant Congress
Use of Letermovir for Cytomegalovirus Management in Thoracic Organ Transplantation
Duke University Medical Center, Durham, NC
*Purpose: Cytomegalovirus (CMV) commonly affects thoracic solid organ transplant (SOT) recipients, and standard antiviral therapies are limited by myelosuppression, renal dysfunction, and emergence of resistance.…2020 American Transplant Congress
A Comprehensive Evaluation of Risk Factors for Pneumocystis Jiroveci Pneumonia in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis
*Purpose: Pneumocytis jiroveci pneumonia (PJP) is an important opportunistic fungal infection in solid organ transplant (SOT) recipients that carries a significant morbidity and mortality. Several…2020 American Transplant Congress
Single Center Experience of Valganciclovir and Adjunctive CMV IVIG for the Treatment of CMV Infection in Lung Transplant Recipients
*Purpose: Cytomegalovirus(CMV) infection happens commonly and causes significant morbidity in lung transplant (LTx) recipients. The use of CMV hyperimmune globulin (CMVIg) as an adjunctive treatment…2020 American Transplant Congress
Letermovir Treatment for Established Cytomegalovirus Infection in Transplant Recipients
*Purpose: The purpose of the study was to describe the patterns of use and clinical/virologic outcomes of letermovir treatment for established CMV infection in transplant…2020 American Transplant Congress
Comparison of Prophylaxis Strategies for CMV Infection in Liver Transplant Recipients
The Ohio State Wexner Medical Center, Columbus, OH
*Purpose: The best strategy to prevent cytomegalovirus (CMV) following liver transplantation is not defined for intermediate risk recipients (recipient seropositive (R+) regardless of donor status).…2020 American Transplant Congress
Epidemiology Cytomegalovirus Infection/Disease in Kidney Transplant Recipients: A Systematic Review of Observational Studies
1Merck & Co., Inc., Kenilworth, NJ, 2Evidera, Inc., Waltham, MA, 3Tufts Medical Center, Boston, MA
*Purpose: Efficacy of several CMV anti-viral strategies has been shown in controlled trials for CMV infection/disease in kidney transplant recipients (KTRs). However, a comprehensive analysis…2020 American Transplant Congress
Cytomegalovirus Infection and Disease in Pediatric Liver Transplantation: Burden of Disease Under a Preemptive Therapy Approach
Transplant Department, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico
*Purpose: To report the incidence cytomegalovirus (CMV) infection (CMV-I) and disease (CMV-D) in a cohort of pediatric liver transplant recipients under preemptive therapy, identify risk…2020 American Transplant Congress
Cytomegalovirus Preemptive Monitoring Conversion and the Use of a Preemptive Threshold after Solid Organ Transplant
*Purpose: Cytomegalovirus (CMV) in solid organ transplant (SOT) is associated with negative graft and patient outcomes. Prophylactic agents of choice have substantial cytotoxicity, and patients…2020 American Transplant Congress
Pharmacist Management after Preemptive Monitoring Conversion as a Component of a Cytomegalovirus Antiviral Stewardship Program at a Large Transplant Center
*Purpose: Cytomegalovirus (CMV) in solid organ transplant (SOT) is associated with negative graft and patient outcomes. Prophylactic agents of choice have substantial cytotoxicity, and patients…2020 American Transplant Congress
Low Level CMV Detection and Effectiveness of Low Dose Valganciclovir Prophylaxis in Intermediate-Risk Liver Transplant Recipients
*Purpose: The purpose of this study is to assess the efficacy of low dose (450 mg/day) valganciclovir in preventing CMV infection in intermediate-risk liver transplant…
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