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Articles tagged "Biopsy"

  • 2015 American Transplant Congress

    The Influence of Immunosuppressive Drugs On the Epithelial Microenvironment in Solid Organ Transplantation – Identification of Biomarker Candidates for Rejection Vs. Tolerance

    A. Akhdar,1 B. Mueller,2 C. Neudoerfl,1 F. Lehner,3 M. Stevanovic-Meyer,1 K. Daemen,1 J. Keil,1 H. Haller,4 C. Blume,4,5 C. Falk.1,6

    1Institute of Transplant Immunology, IFB-Tx, Hanover Medical School, Hanover, Germany; 2MorphoSys, Munich, Germany; 3Department of General, Visceral and Transplantation Surgery, Hanover Medical School, Hanover, Germany; 4Department of Nephrology and Hypertension, Hanover Medical School, Hanover, Germany; 5Institute of Technical Chemistry, Leibniz University Hanover, Hanover, Germany; 6German Center for Infection Research, Braunschweig, Germany.

    In the context of kidney transplantation, NK cells may play an important role by targeting the allogeneic organ due to "missing-self recognition", which leads to…
  • 2015 American Transplant Congress

    Multicenter Validation of a Molecular Diagnostic for Antibody-Mediated Rejection in Formalin-Fixed Paraffin-Embedded Human Renal Allograft Biopsies

    B. Adam,1 B. Afzali,1 N. Shah,1 K. Dominy,2 R. Gill,1 L. Hidalgo,1 P. Campbell,1 C. Roufosse,2 M. Mengel,1 B. Sis.1

    1University of Alberta, Edmonton, Canada; 2Imperial College, London, United Kingdom.

    Background: In 2013, the Banff classification adopted molecular diagnostics as an adjunct for the diagnosis of antibody-mediated rejection (ABMR) in renal allografts. The NanoString gene…
  • 2015 American Transplant Congress

    Hybrid Ostomy – New Technique in Intestinal Transplantation

    T. Beduschi, J. Garcia, P. Ruiz, A. Tekin, G. Selvaggi, S. Nishida, J. Fan, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Introduction: Many experimental non-invasive methods have been tested to assess the intestinal graft, but none of them proved to be reliable. Biopsy of the intestine…
  • 2015 American Transplant Congress

    Explorative Analysis of ZEUS After 5 Years: Histological Assessment from Biopsy Analyses

    U. Eisenberger,1 K. Budde,1 O. Witzke,1 F. Lehner,1 C. Sommerer,1 R. Wuethrich,3 P. Reinke,1 A. Muehlfeld,1 K. Heller,1 R. Stahl,1 H. Wolters,1 I. Hauser,1 M. Porstner,2 W. Arns.1

    1ZEUS Study Group, Germany; 2Novartis, Pharma, Germany; 3ZEUS Study Group, Switzerland.

    Background: Analysis of pathologists' assessments and histological data allow for deeper insight on patient outcome together with investigator's final clinical diagnoses. Here we present 5…
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