Articles tagged "Biopsy"

2015 American Transplant Congress
A Prospective Comparison of the Completeness of Donor Kidney Biopsies
S. Ahmad,¹ E. Siskind,¹ C. Drachenberg,² J. Bromberg,¹ S. Niederhaus.¹
¹Transplantation, University of Maryland, Baltimore; ²Pathology, University of Maryland, Baltimore.
Background: The use of expanded criteria kidneys has plateaued, possibly due to inadequate pathologic evaluation or lack of a universal grading system. We examined pre-transplant…
2015 American Transplant Congress
Blood Gene Expression at 3 Months Post-Transplantation Predicts 1-Year Histological Features in Renal Transplantation
R. Danger,^1,2 K. Renaudin,^1,3,4 C. Paul,¹ G. Couvrat-Desvergnes,^1,3 J. Lozano,⁵ A. Sanchez-Fueyo,^2,5 V. Meas-Yedid,⁶ J. Olivo-Marin,⁶ E. Thervet,⁷ J. Dantal,^1,3,4 A. Moreau,^1,3,4 J.-P. Duong Van Huyen,⁸ J.-P. Soulillou,^1,3,4 M. Giral,^1,3,4 S. Brouard.^1,3,4
¹INSERM U1064 and ITUN, Nantes, France; ²Department of Liver Sciences, Faculty of Life Sciences & Medicine, MRC Transplant Centre, King's College London, London, United Kingdom; ³Centre Hospitalier Universitaire Hôtel-Dieu, Nantes, France; ⁴Universite de Nantes, Nantes, France; ⁵Liver Unit and Bioinformatic Platform, CIBEREHD, Hospital Clinic Barcelona, Barcelona, Spain; ⁶Unité d'Analyse d'Image Quantitative, Institut Pasteur, Paris, France; ⁷Nephrology Unit, Hôpital Européen Georges Pompidou, Paris, France; ⁸Service d'Anatomie Pathologique, Hôpital Européen Georges Pompidou, Paris, France.
Histological analysis of biopsy at one year is proposed as a reliable tool for assessing renal allograft status, however, a non-invasive method for early prediction…
2015 American Transplant Congress
Clinicopathological Scenarios (CPS) Defined by Viremia, Creatinine and Histology in Polyomavirus Nephropathy Differ in 1st and 2nd (Follow-Up) Biopsy
C. Drachenberg, M. Chaudhry, F. Yang, R. Ugarte, A. Haririan, M. Mavanur, C. Cangro, B. Thomas, N. Costa, E. Ramos, M. Weir, J. Papadimitriou.
Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.
Studies of sequential kidney biopsies (KB) after the diagnosis of polyomavirus allograft nephropathy (PVN) are scarce and clinicopathological evolution of PVN poorly understood. In practice…
2015 American Transplant Congress
Differentially Expressed IL-6Rα and GP130 Genes in Kidney Biopsies (Bxs) Suggests Different Roles of IL-6 Signaling in Antibody (ABMR)- and Cell (CMR)-Mediated Rejection
H. Zhang,¹ D. Thomas,¹ J. Kowalewska,² E. Suviolahti,¹ H. Shafi,² C. Nast,² A. Gertych,² A. Vo,¹ M. Haas,² S. Jordan,¹ M. Toyoda.¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; ²Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: IL-6 exerts immunoregulatory properties through IL-6 receptors, IL-6Rα and gp130. Our previous studies suggested the involvement of antibody-dependent cellular cytotoxicity (ADCC) and its related…