Articles tagged "Biopsy"

2022 American Transplant Congress
The Ontario Anatomic Kidney Score (OAKS) : Quantitative Macroscopic Assessment versus Histological Grading in Pre-transplant Evaluation of Donor Kidneys
J. Mello Offerni¹, D. Matty², H. Abed³, P. Roshanov⁴, A. Sener¹, P. Luke¹
¹Urology, Western University, London, ON, Canada, ²Undergraduate Medical Education, Western University, Schulich School of Medicine & Dentistry, London, ON, Canada, ³Division of Urology, Department of Surgery, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada, ⁴Division of Nephrology, Department of Internal Medicine, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada
*Purpose: Quantitative gross assessment of a kidney has not been used to influence the evaluation to utilize a kidney for transplantation. The Ontario Anatomic Kidney…
2022 American Transplant Congress
Treading the Paradigm Shift: A Single Center Comparative Study of Outcomes Between Pre-Emptive and Early Kidney Transplant with Non Pre-Emptive Kidney Transplant Recipients Innational Kidney and Transplant Institute
E. U. Go, L. Baloloy
Organ Transplantation and Vascular Surgery, National Kidney and Transplant Institute, Quezon City, Philippines
*Purpose: To compare the 3-year outcome of pre-emptive and early kidney transplant recipients versus non pre-emptive recipients in our institution from January 2013 to December…
2022 American Transplant Congress
Biopsy Characteristics of Kidneys from a Single Large OPO
S. Bunnapradist¹, T. Seto², A. Cohen², T. Rosenthal¹, G. Danovitch¹
¹David Geffen School of Medicine, Los Angeles, CA, ²One Legacy, Los Angeles, CA
*Purpose: As deceased donor pool have expanded, kidney biopsy has been increasingly used to help determine organ suitability for transplant. There are concerns that biopsy…
2022 American Transplant Congress
Top Molecules Associated with CLAD in Lung Transplants Are Shared Between Mucosal Biopsies, Transbronchial Biopsies, and Kidney Transplant Biopsies at Risk of Progression
M. Mackova¹, K. Halloran², P. F. Halloran¹, .. and the INTERLUNG Study Group³
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: Chronic lung allograft dysfunction (CLAD) is a physiologic state with grave consequences for progression to failure but cannot be diagnosed by biopsy histology. We…
2022 American Transplant Congress
Prospective Study of Preimplantation Biopsy in Deceased Donor Kidney Transplantation (DDKT)
H. Me, M. Smith, C. Jadlowiec, K. Harris, R. Butterfield, H. Khamash, B. G. AbuJawdeh, K. Reddy, R. Heilman
Mayo Clinic, Phoenix, AZ
*Purpose: Our aim was to study the impact of preimplantation biopsy (Bx) findings in selecting kidneys from more marginal donors.*Methods: This is a 2-year prospective…
2022 American Transplant Congress
Prospective Evaluation of Donor-Derived Cell-Free DNA (dd-cfDNA) in Monitoring Response to Anti-Rejection Treatment in Kidney Transplant Recipients with Indication Biopsy
L. Benning¹, A. Fink², F. Kälble¹, C. Speer¹, C. Nusshag¹, M. Zeier¹, C. Süsal³, C. Morath¹, T. Tran²
¹Department of Nephrology, University Hospital Heidelberg, Heidelberg, Germany, ²Transplantation Immunology, Institute of Immunology, University Hospital Heidelberg, Heidelberg, Germany, ³Transplant Immunology Research Center of Excellence, Koç University Hospital, Istanbul, Turkey
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a marker of allograft injury in kidney transplant recipients (KTR). Little is known about the possible use of dd-cfDNA…
2022 American Transplant Congress
Evaluation of the Significance of Isolated C4d Staining without Histological Evidence of Rejection on Kidney Biopsies After ABO-Compatible Transplantation in Pediatric Recipients
C. Duneton¹, M. Rabant², J. Duong-Van-Huyen², V. Baudouin¹, E. Cheyssac¹, O. Boyer³, J. Hogan¹
¹Pediatric Nephrology, Robert Debré Hospital, APHP, Paris, France, ²Pathology, Necker Hospital, Paris, France, ³Pediatric Nephrology, Necker Hospital, Paris, France
*Purpose: C4d staining in peritubular capillaries has been part of ABMR Banff definition since 2003. Despite relatively high specificity, c4d staining shows limited sensitivity, and…
2022 American Transplant Congress
Transbronchial Cryobiopsy vs Conventional Forceps Biopsy in Lung Transplant Recipients Multicenter Study
M. Svorcova¹, J. Vachtenheim¹, J. Havlin¹, P. Jakubec², D. Rakita³, J. Balko⁴, J. Simonek¹, J. Kolarik¹, J. Pozniak¹, R. Lischke¹
¹3rd Surgery Department, 1st Faculty of Medicine, Charles University in Prague and Motol University, National Lung Transplant Program Prague, Prague, Czech Republic, ²Department of respiratory disease and tuberculosis, University Hospital Olomouc, Olomouc, Czech Republic, ³Department of pneumology, 2nd Faculty of Medicine, Charles University in Prague and Motol University, Prague, Czech Republic, ⁴Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and Motol University, Prague, Czech Republic
*Purpose: Transbronchial biopsy is considered the gold standard in the diagnosis of acute cellular rejection after lung transplantation. There still remains the discussion in conventional…
2022 American Transplant Congress
Histopathology at Diagnosis and One-Year Outcomes in Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Preliminary Findings from the Paramour “Pediatric Renal AMR Outcomes” Study
R. Zahr¹, D. Puliyanda², I. Ashoor³, N. Hayde⁴, S. Solomon⁵, R. Engen⁶, L. Harshman⁷, C. Peterson⁸, S. McEwen⁹, A. Jain¹⁰, R. Garro¹¹, A. Mansuri¹², M. Kallash¹³, K. Twombley¹⁴
¹Pediatrics, University of Tennessee Health Science Center, Memphis, TN, ²Cedars-Sinai Med Ctr, West Hollywood, CA, ³Pediatrics, Lousiana State University, New Orleans, LA, ⁴Montefiore Medical Center, Bronx, NY, ⁵The Children's Hospital at Montefiore, New York, NY, ⁶Pediatrics, University of Wisconsin Madison, Madison, WI, ⁷University of Iowa Children's Hospital, Iowa City, IA, ⁸University of Utah, Salt Lake City, UT, ⁹University of Minnesota, Minneapolis, MN, ¹⁰Pediatrics, Wayne State University, Troy, MI, ¹¹Emory University, Atlanta, GA, ¹²Pediatrics, Augusta University, Augusta, GA, ¹³Pediatrics, The Ohio State Univesrity, Columbus, OH, ¹⁴Medical University of South Carolina, Charleston, SC
*Purpose: Antibody mediated rejection (AMR) is a major cause of kidney allograft dysfunction leading to graft loss. There is a paucity of data regarding how…
2022 American Transplant Congress
Diagnostic Performance of Donor-Derived Cell-Free DNA Assay (AlloSure®) in Kidney Transplant Recipients with Graft Dysfunction: A Single Center Study
M. S. Naseer¹, H. Shokouh-Amiri², T. Creamer¹, R. McMillan², S. Tandukar¹, D. Aultman¹, G. B. Zibari¹, N. Singh¹
¹Transplant, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, ²John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA
*Purpose: Circulating donor-derived cell-free DNA (dd-cf-DNA) is a non-invasive biomarker of kidney allograft injury with a high negative predictive value for ruling out active rejection…