2018 American Transplant Congress
Medullary Tissue Sampling in Renal Allograft Biopsy is More Sensitive for Pathologic Diagnosis of PVN
Background Post-transplant polyoma virus nephropathy (PVN) prevalence is 1-10%. Definitive PVN diagnosis requires polyoma virus presence in infected cells, done with immunohistochemical staining for SV40…2018 American Transplant Congress
Real-Time Expert Evaluation of Liver Biopsy for Transplant: The Significance of Smartphone and Microscope Adapter in Telepathology
Introduction: Liver biopsy at the time of procurement plays a crucial role in the acceptance of marginal grafts. Local pathologists and transplant surgery fellows are…2018 American Transplant Congress
Assessing Fibrosis Burden in Renal Allograft with Chronic Damage Using Functional Magnetic Resonance Imaging
Background: Renal allograft fibrosis burden is a strong prognosticator for chronic damage and can only be accurately measured through transplant biopsy at present. We hypothesized…2018 American Transplant Congress
Non-Invasive Proteomics to Detect Biomarkers for Kidney Allograft Dysfunction
Background: Non-invasive biomarkers are needed for monitoring patients to predict early acute rejection (AR). We hypothesized that protein biomarkers released from rejecting allograft tissues can…2018 American Transplant Congress
Reliability of Deceased Donor Procurement Biopsy Images at the Time of Kidney Allocation
Histological findings of procurement deceased-donor kidney biopsies contribute to organ allocation decisions. Representative images of pathology on biopsy slides are often uploaded into United Network…2018 American Transplant Congress
Angiotensin II Type 1 Receptor Antibodies as Markers of Post Transplant Focal Segmental Glomerulosclerosis and Proteinuria
Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD.
Background:Angiotensin II type 1 receptor (AT1R) is highly expressed on the endothelial cells and podocytes, which play an essential role in the maintenance of vascular…2018 American Transplant Congress
Complex Combined Thoracic/liver Transplant: A Seven Year Experience
Liver and Pancreas Transplant, UCLA, Los Angeles, CA.
Background: While rare, combined Thoracic/Liver transplants are employed with increasing frequency. Consistent data regarding the technical conduct, patient selection and outcomes in this highly complex…2018 American Transplant Congress
Intragraft MicroRNA Transcriptome of Acute Antibody Mediated Rejection of Human Kidney Allografts
1Weill Cornell Medicine, New York; 2Rockefeller University, New York.
BackgroundMicroRNAs (miRNA) are master regulators of gene expression and are potential therapeutic targets. Intragraft miRNA transcriptome of acute antibody rejection (AMR) of human kidney allograft…2018 American Transplant Congress
Early Allograft Biopsy in Kidney Transplant Recipients with DGF – Call for an Individualized Approach
Transplant Surgery, Medstar Georgetown Transplant Institute, Washington, DC.
Introduction:With the use of potent induction and maintenance immunosuppressive therapy, routine early/protocol biopsy in DGF patients is questionable.AimThis study aimed to determine the incidence of…2018 American Transplant Congress
C4d Staining and Graft Survival in Renal Transplant Recipients
Nephrology and Transplant, Henry Ford Hospital, Detroit, MI.
Introduction: C4d staining in peritubular capillaries strongly correlates with presence of acute or chronic antibody mediated rejection (AMR). Data on the significance of variable C4d…
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