2019 American Transplant Congress
Occult Liver Graft Fibrosis Prior to Transplantation Influences Clinical Outcomes
Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Liver transplantation (LT) has become a standard therapy for the management of end-stage liver disease, while early allograft dysfunction (EAD) remains a serious problem.…2019 American Transplant Congress
Graft TIM4 Deficiency Protects Liver from Ischemia Reperfusion Injury: From Mouse to Human
*Purpose: Liver ischemia-reperfusion injury (IRI) is a major risk factor for early graft dysfunction and rejection in orthotopic liver transplantation (OLT). We and others have…2019 American Transplant Congress
Urinary Podocin mRNA as Predictor of Renal Allograft Function Decline
*Purpose: Traditional biomarkers (such as proteinuria, 1year eGFR) as well as validated risk prediction tools such as the Birmingham Risk Score predict risk of ESRD.…2019 American Transplant Congress
Clinical Outcomes and Risk Factors for Delayed or Slow Graft Function in an Adult, Urban Renal Transplant Population
University of Illinois at Chicago, Chicago, IL
*Purpose: Delayed graft function (DGF) and slow graft function (SGF) are shown to be associated with higher risk of rejection and suboptimal allograft function over…2019 American Transplant Congress
International Multicenter Study Evaluating Clinical Outcomes Associated with Acute Antibody-Mediated Rejection
*Purpose: Evaluating factors that impact clinical outcomes of patients with acute antibody-mediated rejection (aAMR) may help manage and improve outcomes following kidney transplant. The objective…2018 American Transplant Congress
Immunophenotype of Cells Infiltrating the Graft Explains the Benefits of Belatacept
Previously, we found greater amounts of FoxP3 cells and lower amounts of CD4+/IL-17A+ and senescent cells in belatacept (Bela) patients compared to patients under cyclosporine…2018 American Transplant Congress
Global Expression Profiles of miRNA and Expression Patterns and Localization of the miR-21 in One-Hour Biopsy Specimens of Human Kidney Tansplantation from Donors after Cardiac Death
Because of the global shortage of renal grafts, kidney transplantation (KTx) from donors after cardiac death (DCDs) is an alternative way of obtaining KTx from…2018 American Transplant Congress
Components of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBX) Impacting Late Death Censored Graft Failure (DCGF)
Recent studies document that MVI increases DCGF. However, the relationship between components of MVI (Banff scores g, cg, ptc) and macrovascular inflammation (v) have not…2018 American Transplant Congress
Pump Resistive Index Values and Not Preimplantation Kidney Biopsy Predict Kidney Allograft Survival
AimTo investigate the relationship between histological findings of preimplantation kidney biopsies and pump resistive index (RI) values during machine preservation and subsequent allograft survival.MethodsWe retrospectively…2018 American Transplant Congress
Tissue Talks: Graft´s Histological Findings 10 Years after Belatacept or CNI
The BENEFIT study demonstrated that 7 yrs after kidney transplantation (KT), mean eGFR, patient and graft survival, were significantly higher in the belatacept group than…
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