ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Biopsy"

  • 2019 American Transplant Congress

    Role of Procurement and Reperfusion Biopsy in Kidney Transplant in Evaluating and Predicting Outcomes of Deceased Donor Kidneys

    S. Faiz, A. Pai, A. De Golovine, A. Edwards, W. Glass, A. Tchakarov

    UT Houston, Houston, TX

    *Purpose: Pathologic assessment of donor organs by use of procurement biopsies (PB) provides information regarding organ quality. Most commonly cited reason for organ discard is…
  • 2019 American Transplant Congress

    Urinary Biomarkers- CXCL9 and CXCL10 for Non-Invasive, Early Diagnosis of Rejection in Pediatric Renal Transplantation

    R. P. George1, B. Hanberry2, I. Dave2, B. Lee2, R. Garro1, C. McCracken2, B. Warshaw1

    1Pediatrics, Emory University and Children's Healthcare of Atlanta, Atlanta, GA, 2Pediatrics, Emory University, Atlanta, GA

    *Purpose: Renal transplantation is the treatment of choice for End Stage Renal Disease, but requires strict medication adherence and lifelong surveillance for rejection, infection and…
  • 2019 American Transplant Congress

    Evaluation of Pretransplant Biopsy as a Influence Factor of Early Graft Function after Donated Kidney Transplantation

    X. Qiuxiang, W. Zhendi

    Urology Surgery, Wuhan Union Hospital, Wuhan, China

    *Purpose: To investigate the relationship between pretransplant biopsy and the early graft function after donated kidney transplantation.*Methods: We examined pretransplant biopsies for 240 kidney transplant…
  • 2019 American Transplant Congress

    The Crucial Role of Molecular Microscope in the Interpretation of Ambiguous Lesions Such as Banff Borderline Changes and Tubulo-Interstitial Inflammation Accompanying PVAN

    D. Deborska-Materkowska1, A. Perkowska-Ptasinska1, M. Ciszek1, P. F. Halloran2, M. Myslak3

    1Warsaw Medical University, Warsaw, Poland, 2ATAGC, University of Alberta, Edmonton AB, AB, Canada, 3Pomeranian Medical University, Szczecin, Poland

    *Purpose: Anti-rejection treatment implementation is highly dependent on morphologic lesions interpretation based on Banff classification. Unfortunately, some light microscopic phenotypes are ambiguous which constricts the…
  • 2019 American Transplant Congress

    Organ Vigilance in Germany: Malignancy Transmission from Organ Donor to Recipient

    K. Moench, A. Rahmel, A. P. Barreiros

    German Foundation for Organtransplantation, Frankfurt, Germany

    *Purpose: Vigilance monitoring after organ transplantation includes Serious Adverse Events (SAE) and Serious Adverse Reactions (SAR). SAE describe findings in the donor after transplant that…
  • 2018 American Transplant Congress

    Effect of Acute Vascular Inflammation (v) on Death Censored Graft Failure (DCGF) Following Kidney Transplant (KTx)

    J. Grande,1 L. Hunsicker,2 R. LeDuc,3 A. Matas, The DeKAF Consortium.

    1Pathology, Mayo Clinic, Rochester, MN; 2Int. Med., U Iowa, Iowa City, IA; 3Biostatistics and Surgery, U Minnesota, Minneapolis, MN.

    The impact of acute vascular inflammation in acute cellular or humoral rejection following KTx, and the effect of isolated vascular inflammatory lesions on late DCGF,…
  • 2018 American Transplant Congress

    Magnitude of Pre-Biopsy Decline in Renal Function and Its Association with Allograft Rejection

    S. Voora,1 P. Ahearn,1 M. Tavakol,2 K. Johansen,1,3 E. Ku.1

    1Division of Nephrology, UCSF, San Francisco, CA; 2Department of Surgery, UCSF, San Francisco, CA; 3Department of Epidemiology/Biostatistics, UCSF, San Francisco, CA.

    Introduction: Acute rejection is a significant cause of morbidity, and transplant biopsy remains the gold standard for diagnosing rejection. To our knowledge there have been…
  • 2018 American Transplant Congress

    Unilateral vs. Bilateral Dual Kidney Transplantation: University of Bologna Experience

    M. Del Gaudio,1 M. Ravaioli,1 C. Zanfi,1 V. Bertuzzo,1 L. Maroni,1 G. La Manna,2 G. Liviano,2 A. Siniscalchi,3 A. D'Errico,4 A. Pinna.1

    1Organ Insufficency and Transplantation/Transplantation Unit Prof. A.D. Pinna, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; 2Organ Insufficency and Transplantation Nephrology Unit G. La Manna, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; 3Organ Insufficency and Transplantation Intensive Care Unit Prof. S. Faenza, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; 4Organ Insufficency and Transplantation Pathology Unit D'Errico, S.Orsola Malpighi Hospital University of Bologna, Bolgona, Italy.

    One option for using organs from donors with a suboptimal nephron mass, e.g. expanded criteria donors (ECD) kidneys, is dual kidney transplantation (DKT)Methods: Ninety-three DKT…
  • 2018 American Transplant Congress

    Factor Analysis (FA) of Renal Transplant Biopsy (KTxBx) Data Enables Objective Assessment of Risk for Subsequent Death Censored Graft Failure (DCGF)

    L. Hunsicker,1 J. Grande,2 J. Cecka,3 A. Matas,4 The DeKaf Consortium.

    1Int. Med., UIowa, Iowa City, IA; 2Pathology, Mayo Clinic, Rochester, MN; 3Immunogenetics, UCLA, Los Angeles, CA; 4Surgery, U Minnesota, Minneapolis, MN.

    We examined the impact of five axes of injury identified by FA in the KTxBx on the hazard for subsequent DCGF in two DeKAF cohorts.Methods:…
  • 2018 American Transplant Congress

    A Substantial Fraction of Surveillance Transplant Biopsies Have Clinically Actionable Findings

    A. Shammout,1 A. Naik,2 M. Samaniego,2 E. Farkash.1

    1Pathology, Michigan Medicine, Ann Arbor; 2Nephrology, Michigan Medicine, Ann Arbor.

    Background: Surveillance biopsies in renal transplant recipients may detect subclinical disease that affects graft longevity. At our transplant center, most patients with stable allograft function…
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